6OVT

Crystal Structure of IlvD from Mycobacterium tuberculosis

Summary for 6OVT

• Entry DOI: 10.2210/pdb6ovt/pdb
• Descriptor: Dihydroxy-acid dehydratase, MAGNESIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... (6 entities in total)
• Functional Keywords: dihydroxy-acid dehydratase 2, 3-dihydroxy-3-methylbutanoate 3-methyl-2-oxobutanoate, lyase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 4
• Total formula weight: 251575.68

Authors

Almo, S.C.,Grove, T.L.,Bonanno, J.B.,Baker, E.N.,Bashiri, G. (deposition date: 2019-05-08, release date: 2019-08-07, Last modification date: 2019-12-18)

• Primary citation: Bashiri, G.,Grove, T.L.,Hegde, S.S.,Lagautriere, T.,Gerfen, G.J.,Almo, S.C.,Squire, C.J.,Blanchard, J.S.,Baker, E.N.; The active site of theMycobacterium tuberculosisbranched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe-2S cluster.; J.Biol.Chem., 294:13158-13170, 2019; PubMed: 31315931; DOI: 10.1074/jbc.RA119.009498

Experimental method

X-RAY DIFFRACTION (1.88 Å)