1TY0

Crystal structure of the streptococcal pyrogenic exotoxin J (SPE-J)

Summary for 1TY0

• Entry DOI: 10.2210/pdb1ty0/pdb
• Related: 1ty2
• Descriptor: putative exotoxin (superantigen) (2 entities in total)
• Functional Keywords: superantigen, t-cell receptor binding, mutagenesis, dimerization, immune system
• Biological source: Streptococcus pyogenes
• Total number of polymer chains: 3
• Total formula weight: 74408.91

Authors

Baker, H.M.,Proft, T.,Webb, P.D.,Arcus, V.L.,Fraser, J.D.,Baker, E.N. (deposition date: 2004-07-06, release date: 2004-08-03, Last modification date: 2024-04-03)

• Primary citation: Baker, H.M.,Proft, T.,Webb, P.D.,Arcus, V.L.,Fraser, J.D.,Baker, E.N.; Crystallographic and mutational data show that the streptococcal pyrogenic exotoxin j can use a common binding surface for T-cell receptor binding and dimerization; J.Biol.Chem., 279:38571-38576, 2004; PubMed: 15247241; DOI: 10.1074/jbc.M406695200

Experimental method

X-RAY DIFFRACTION (1.75 Å)