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Crystal structure of A/Victoria/361/2011 (H3N2) influenza virus hemagglutinin
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者	Lee, P.S, Wilson, I.A.
登録日	2013-12-19
公開日	2014-04-16
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus. Nat Commun, 5, 2014

4O5I

Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/361/2011 (H3N2) influenza hemagglutinin
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab F045-092 heavy chain, ...
著者	Lee, P.S, Wilson, I.A.
登録日	2013-12-19
公開日	2014-04-16
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (6.501 Å)
主引用文献	Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus. Nat Commun, 5, 2014

4N61

Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with LSTa, extended soaking
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
著者	Xu, R, Wilson, I.A.
登録日	2013-10-11
公開日	2013-12-18
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2.6023 Å)
主引用文献	Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science, 342, 2013

4NZR

Crystal structure of the antibody-binding region of Protein M (Protein M TD) in complex with anti-HIV antibody PGT135 Fab
分子名称:	GLYCEROL, PGT135 heavy chain, PGT135 light chain, ...
著者	Zhu, X, Wilson, I.A.
登録日	2013-12-12
公開日	2014-02-19
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (1.65 Å)
主引用文献	A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union. Science, 343, 2014

4NWU

Crystal structure of APE1551, an anti-human NGF Fab with a nine amino acid insertion in CDR H1
分子名称:	APE1551 Ab Fab heavy chain, APE1551 Ab Fab light chain
著者	Verdino, P, Stanfield, R.L, Wilson, I.A.
登録日	2013-12-06
公開日	2014-10-22
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (1.602 Å)
主引用文献	Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies. J.Biol.Chem., 289, 2014

4MZA

Crystal structure of hPIV3 hemagglutinin-neuraminidase
分子名称:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者	Xu, R, Wilson, I.A.
登録日	2013-09-29
公開日	2013-11-06
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (1.653 Å)
主引用文献	Interaction between the hemagglutinin-neuraminidase and fusion glycoproteins of human parainfluenza virus type III regulates viral growth in vivo. MBio, 4, 2013

4N5Y

Crystal structure of H5 hemagglutinin mutant (N158D, N224K and Q226L) from the influenza virus A/Viet Nam/1203/2004 (H5N1)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者	Zhu, X, Wilson, I.A.
登録日	2013-10-10
公開日	2013-11-20
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (3.1615 Å)
主引用文献	Hemagglutinin Receptor Specificity and Structural Analyses of Respiratory Droplet-Transmissible H5N1 Viruses. J.Virol., 88, 2014

4N5Z

Crystal structure of aerosol transmissible influenza H5 hemagglutinin mutant (N158D, N224K, Q226L and T318I) from the influenza virus A/Viet Nam/1203/2004 (H5N1)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者	Zhu, X, Wilson, I.A.
登録日	2013-10-10
公開日	2013-11-20
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.9537 Å)
主引用文献	Hemagglutinin Receptor Specificity and Structural Analyses of Respiratory Droplet-Transmissible H5N1 Viruses. J.Virol., 88, 2014

4NGH

Crystal structure of the HIV-1 neutralizing antibody 4E10 Fab fragment in complex with a hydrocarbon-stapled peptide containing the 4e10 epitope on gp41 and a tethered phosphate moiety.
分子名称:	FAB HEAVY CHAIN, FAB LIGHT CHAIN, MODIFIED FRAGMENT OF HIV GLYCOPROTEIN (GP41)
著者	Irimia, A, Wilson, I.A.
登録日	2013-11-01
公開日	2014-12-03
最終更新日	2023-12-06
実験手法	X-RAY DIFFRACTION (2.68 Å)
主引用文献	Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies. Nat.Struct.Mol.Biol., 21, 2014

4N60

Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with LSTc
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
著者	Xu, R, Wilson, I.A.
登録日	2013-10-11
公開日	2013-12-18
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2.9032 Å)
主引用文献	Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science, 342, 2013

4N62

Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with a sulfated receptor analog
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
著者	Xu, R, Wilson, I.A.
登録日	2013-10-11
公開日	2013-12-18
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2.5026 Å)
主引用文献	Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science, 342, 2013

4N63

Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with an O-linked glycan receptor
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
著者	Xu, R, Wilson, I.A.
登録日	2013-10-11
公開日	2013-12-18
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.7522 Å)
主引用文献	Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science, 342, 2013

4NCO

Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP gp120, BG505 SOSIP gp41, ...
著者	Julien, J.-P, Stanfield, R.L, Lyumkis, D, Ward, A.B, Wilson, I.A.
登録日	2013-10-24
公開日	2013-11-13
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (4.7 Å)
主引用文献	Crystal structure of a soluble cleaved HIV-1 envelope trimer. Science, 342, 2013

4NJ9

Crystal structure of Fab 8B10 in complex with MPTS
分子名称:	8-methoxypyrene-1,3,6-trisulfonic acid, 8B10 heavy chain, 8B10 light chain, ...
著者	Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A.
登録日	2013-11-08
公開日	2014-11-12
最終更新日	2017-06-14
実験手法	X-RAY DIFFRACTION (1.95 Å)
主引用文献	Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation. Biochemistry, 54, 2015

4NPY

Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody
分子名称:	GLYCEROL, germline PGT121 heavy chain, germline PGT121 light chain
著者	Julien, J.-P, Diwanji, D.C, Wilson, I.A.
登録日	2013-11-22
公開日	2013-12-11
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (1.796 Å)
主引用文献	The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies. Plos Pathog., 9, 2013

4N5K

Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with LSTa
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
著者	Xu, R, Wilson, I.A.
登録日	2013-10-10
公開日	2013-12-18
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2.7053 Å)
主引用文献	Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science, 342, 2013

4MWF

Structure of Hepatitis C Virus Envelope Glycoprotein E2 core bound to broadly neutralizing antibody AR3C
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者	Kong, L, Wilson, I.A, Law, M.
登録日	2013-09-24
公開日	2013-12-11
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2.645 Å)
主引用文献	Hepatitis C virus e2 envelope glycoprotein core structure. Science, 342, 2013

4N5J

Crystal structure of hemagglutinin from an H7N9 influenza virus
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
著者	Xu, R, Wilson, I.A.
登録日	2013-10-10
公開日	2013-12-18
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (2.702 Å)
主引用文献	Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science, 342, 2013

4N64

Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with a biantennary glycan receptor
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
著者	Xu, R, Wilson, I.A.
登録日	2013-10-11
公開日	2013-12-18
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.7014 Å)
主引用文献	Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science, 342, 2013

4QDH

Crystal Structure of the C-terminal Domain of Mouse TLR9
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variable lymphocyte receptor B, ...
著者	Collins, B.C, Wilson, I.A.
登録日	2014-05-13
公開日	2014-06-11
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.399 Å)
主引用文献	Crystal structure of the C-terminal domain of mouse TLR9. Proteins, 82, 2014

4N0Y

Structure of the Hepatitis C Envelope Glycoprotein E1 antigenic region 314-324 bound to the cross-neutralizing antibody IGH526
分子名称:	CHLORIDE ION, GLYCEROL, HCV E1 peptide, ...
著者	Kong, L, Wilson, I.A.
登録日	2013-10-02
公開日	2015-04-01
最終更新日	2015-08-26
実験手法	X-RAY DIFFRACTION (1.749 Å)
主引用文献	Structure of Hepatitis C Virus Envelope Glycoprotein E1 Antigenic Site 314-324 in Complex with Antibody IGH526. J.Mol.Biol., 427, 2015

4QGT

The Crystal Structure of Human IgG Fc Domain with Enhanced Aromatic Sequon
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者	Kong, L, Connelly, S.C, Wilson, I.A.
登録日	2014-05-25
公開日	2015-04-08
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.99 Å)
主引用文献	Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon. Acs Chem.Biol., 11, 2016

3OAZ

A non-self sugar mimic of the HIV glycan shield shows enhanced antigenicity
分子名称:	CHLORIDE ION, Fab 2G12, heavy chain, ...
著者	Doores, K.J, Fulton, Z, Hong, V, Patel, M.K, Scanlan, C.N, Wormald, M.R, Finn, M.G, Burton, D.R, Wilson, I.A, Davis, B.G.
登録日	2010-08-06
公開日	2011-01-12
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity. Proc.Natl.Acad.Sci.USA, 107, 2010

3O2V

Crystal structure of 1E9 PheL89Ser/LeuH47Trp/MetH100bPhe, an engineered Diels-Alderase Fab with modified specificity and catalytic activity
分子名称:	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CITRATE ANION, Chimeric antibody Fab 1E9, ...
著者	Verdino, P, Wilson, I.A.
登録日	2010-07-22
公開日	2011-07-20
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystal structure of 1E9 PheL89Ser/LeuH47Trp/MetH100bPhe, an engineered Diels-Alderase Fab with modified specificity and catalytic activity To be Published

3OZ9

Crystal Structure of anti-gp41 Fab NC-1
分子名称:	Fab NC-1 IgG2a heavy chain, Fab NC-1 kappa light chain, GLYCEROL
著者	Stanfield, R.L, Calarese, D.A, Jiang, S, Wilson, I.A.
登録日	2010-09-24
公開日	2010-10-06
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Crystal Structure of anti-gp41 Fab NC-1 TO BE PUBLISHED

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