7OLS
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![BU of 7ols by Molmil](/molmil-images/mine/7ols) | MerTK kinase domain with type 1.5 inhibitor containing a di-methyl pyrazole group | 分子名称: | 5-[4-(1,5-dimethylpyrazol-4-yl)-2-methyl-phenyl]-~{N}-(imidazo[1,2-a]pyridin-6-ylmethyl)-~{N}-methyl-1,3,4-oxadiazol-2-amine, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Pflug, A, Schimpl, M, McCoull, W, Nissink, J.W.M, Winter-Holt, J. | 登録日 | 2021-05-20 | 公開日 | 2021-09-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Optimization of an Imidazo[1,2- a ]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy. J.Med.Chem., 64, 2021
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7OLV
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![BU of 7olv by Molmil](/molmil-images/mine/7olv) | MerTK kinase domain with type 1.5 inhibitor containing a di-methyl, cyano pyrazole group | 分子名称: | 4-[4-[5-[imidazo[1,2-a]pyridin-6-ylmethyl(methyl)amino]-1,3,4-oxadiazol-2-yl]-3-methyl-phenyl]-2,5-dimethyl-pyrazole-3-carbonitrile, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Pflug, A, Schimpl, M, McCoull, W, Nissink, J.W.M, Winter-Holt, J. | 登録日 | 2021-05-20 | 公開日 | 2021-09-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Optimization of an Imidazo[1,2- a ]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy. J.Med.Chem., 64, 2021
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8G3V
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8G3Z
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![BU of 8g3z by Molmil](/molmil-images/mine/8g3z) | |
8G30
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8G3Q
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8G3R
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8G3O
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![BU of 8g3o by Molmil](/molmil-images/mine/8g3o) | N2 neuraminidase of A/Hong_Kong/2671/2019 in complex with 3 FNI9 Fab molecules | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Dang, H.V, Snell, G. | 登録日 | 2023-02-08 | 公開日 | 2023-05-31 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | A pan-influenza antibody inhibiting neuraminidase via receptor mimicry. Nature, 618, 2023
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8G3M
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8G3N
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![BU of 8g3n by Molmil](/molmil-images/mine/8g3n) | N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with 4 FNI9 Fab molecules | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Dang, H, Snell, G. | 登録日 | 2023-02-08 | 公開日 | 2023-05-31 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | A pan-influenza antibody inhibiting neuraminidase via receptor mimicry. Nature, 618, 2023
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8G40
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![BU of 8g40 by Molmil](/molmil-images/mine/8g40) | N2 neuraminidase of A/Hong_Kong/2671/2019 in complex with 3 FNI19 Fab molecules | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Dang, H.V, Snell, G. | 登録日 | 2023-02-08 | 公開日 | 2023-05-31 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | A pan-influenza antibody inhibiting neuraminidase via receptor mimicry. Nature, 618, 2023
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8G3P
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![BU of 8g3p by Molmil](/molmil-images/mine/8g3p) | N2 neuraminidase of A/Hong_Kong/2671/2019 in complex with 4 FNI9 Fab molecules | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Dang, H.V, Snell, G. | 登録日 | 2023-02-08 | 公開日 | 2023-05-31 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | A pan-influenza antibody inhibiting neuraminidase via receptor mimicry. Nature, 618, 2023
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6W2E
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![BU of 6w2e by Molmil](/molmil-images/mine/6w2e) | Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | 著者 | Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H. | 登録日 | 2020-03-05 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus. Nat Microbiol, 5, 2020
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6W19
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![BU of 6w19 by Molmil](/molmil-images/mine/6w19) | Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus | 分子名称: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | 著者 | Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H. | 登録日 | 2020-03-03 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus. Nat Microbiol, 5, 2020
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5WPW
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6W2D
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![BU of 6w2d by Molmil](/molmil-images/mine/6w2d) | Structures of Capsid and Capsid-Associated Tegument Complex inside the Epstein-Barr Virus | 分子名称: | Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... | 著者 | Liu, W, Cui, Y.X, Wang, C.Y, Li, Z.H, Gong, D.Y, Dai, X.H, Bi, G.Q, Sun, R, Zhou, Z.H. | 登録日 | 2020-03-05 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus. Nat Microbiol, 5, 2020
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7DCN
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7DCM
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![BU of 7dcm by Molmil](/molmil-images/mine/7dcm) | Crystal structure of CITX | 分子名称: | Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, ZINC ION | 著者 | Xu, H, Wang, B, Su, X.D. | 登録日 | 2020-10-26 | 公開日 | 2021-11-03 | 最終更新日 | 2023-05-17 | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | 主引用文献 | Co-evolution-based prediction of metal-binding sites in proteomes by machine learning. Nat.Chem.Biol., 19, 2023
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7DLV
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![BU of 7dlv by Molmil](/molmil-images/mine/7dlv) | shrimp dUTPase in complex with Stl | 分子名称: | CALCIUM ION, Orf20, SULFATE ION, ... | 著者 | Ma, Q, Wang, F. | 登録日 | 2020-11-30 | 公開日 | 2021-12-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.525 Å) | 主引用文献 | Structural basis of staphylococcal Stl inhibition on a eukaryotic dUTPase. Int.J.Biol.Macromol., 184, 2021
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4HNA
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6JBR
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![BU of 6jbr by Molmil](/molmil-images/mine/6jbr) | Tps1/UDP/T6P complex | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, Trehalose-6-phosphate synthase, URIDINE-5'-DIPHOSPHATE | 著者 | Wang, S, Zhao, Y, Wang, D, Liu, J. | 登録日 | 2019-01-26 | 公開日 | 2019-12-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1. Biochem.J., 476, 2019
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8ID6
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![BU of 8id6 by Molmil](/molmil-images/mine/8id6) | Cryo-EM structure of the oleic acid bound GPR120-Gi complex | 分子名称: | Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Mao, C, Xiao, P, Tao, X, Qin, J, He, Q, Zhang, C, Yu, X, Zhang, Y, Sun, J. | 登録日 | 2023-02-12 | 公開日 | 2023-03-15 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Science, 380, 2023
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8ID9
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![BU of 8id9 by Molmil](/molmil-images/mine/8id9) | Cryo-EM structure of the eicosapentaenoic acid bound GPR120-Gi complex | 分子名称: | 5,8,11,14,17-EICOSAPENTAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Mao, C, Xiao, P, Tao, X, Qin, J, He, Q, Zhang, C, Yu, X, Zhang, Y, Sun, J. | 登録日 | 2023-02-12 | 公開日 | 2023-03-15 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Science, 380, 2023
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8ID4
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![BU of 8id4 by Molmil](/molmil-images/mine/8id4) | Cryo-EM structure of the linoleic acid bound GPR120-Gi complex | 分子名称: | Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Mao, C, Xiao, P, Tao, X, Qin, J, He, Q, Zhang, C, Yu, X, Zhang, Y, Sun, J. | 登録日 | 2023-02-12 | 公開日 | 2023-03-15 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Science, 380, 2023
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8ID3
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![BU of 8id3 by Molmil](/molmil-images/mine/8id3) | Cryo-EM structure of the 9-hydroxystearic acid bound GPR120-Gi complex | 分子名称: | 9-Hydroxyoctadecanoic acid, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Mao, C, Xiao, P, Tao, X, Qin, J, He, Q, Zhang, C, Yu, X, Zhang, Y, Sun, J. | 登録日 | 2023-02-12 | 公開日 | 2023-03-15 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Science, 380, 2023
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