8G30

N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with 4 FNI19 Fab molecules

Summary for 8G30

• Entry DOI: 10.2210/pdb8g30/pdb
• EMDB information: 29686
• Descriptor: FNI19 Fab heavy chain, FNI19 Fab light chain, Neuraminidase, ... (8 entities in total)
• Functional Keywords: viral glycoprotein, antibody, fab, influenza, virus, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 12
• Total formula weight: 428535.01

Authors

Dang, H.V.,Snell, G. (deposition date: 2023-02-06, release date: 2023-05-31, Last modification date: 2023-06-28)

• Primary citation: Momont, C.,Dang, H.V.,Zatta, F.,Hauser, K.,Wang, C.,di Iulio, J.,Minola, A.,Czudnochowski, N.,De Marco, A.,Branch, K.,Donermeyer, D.,Vyas, S.,Chen, A.,Ferri, E.,Guarino, B.,Powell, A.E.,Spreafico, R.,Yim, S.S.,Balce, D.R.,Bartha, I.,Meury, M.,Croll, T.I.,Belnap, D.M.,Schmid, M.A.,Schaiff, W.T.,Miller, J.L.,Cameroni, E.,Telenti, A.,Virgin, H.W.,Rosen, L.E.,Purcell, L.A.,Lanzavecchia, A.,Snell, G.,Corti, D.,Pizzuto, M.S.; A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.; Nature, 618:590-597, 2023; PubMed: 37258672; DOI: 10.1038/s41586-023-06136-y

Experimental method

ELECTRON MICROSCOPY (3.1 Å)