8G30
N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with 4 FNI19 Fab molecules
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (E, G, H, J) | FNI19 Fab heavy chain | polymer | 231 | 24692.6 | 4 | Homo sapiens | ||
| 2 | B, E, H, K (F, I, L, K) | FNI19 Fab light chain | polymer | 215 | 23549.3 | 4 | Homo sapiens | ||
| 3 | C, F, I, L (M, N, O, P) | Neuraminidase | polymer | 492 | 54755.0 | 4 | UniProt (V9SU56) Pfam (PF00064) UniProt (by SIFTS) (A0A4D6K9W1) | Influenza A virus | |
| 4 | CA, EA, FA, HA, M... (v, 1, 2, 4, a...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 10 | In PDB GlyTouCan (G15407YE) | |||
| 5 | N, Z (b, r) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G22573RC) | |||
| 6 | AA, GA, O, U (s, 3, c, k) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 4 | In PDB GlyTouCan (G80966KZ) | |||
| 7 | BA, DA, IA, JA, Q... (t, w, 6, 7, f...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 8 | In PDB GlyTouCan (G42666HT) | |||
| 8 | KA, LA, MA, NA, OA (M, N, O, P) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) |
Sequence modifications
M, N, O, P: 82 - 469 (UniProt: V9SU56)
| PDB | External Database | Details |
|---|---|---|
| Met -22 | - | initiating methionine |
| Glu -21 | - | expression tag |
| Thr -20 | - | expression tag |
| Asp -19 | - | expression tag |
| Thr -18 | - | expression tag |
| Leu -17 | - | expression tag |
| Leu -16 | - | expression tag |
| Leu -15 | - | expression tag |
| Trp -14 | - | expression tag |
| Val -13 | - | expression tag |
| Leu -12 | - | expression tag |
| Leu -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Trp -9 | - | expression tag |
| Val -8 | - | expression tag |
| Pro -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Thr -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Asp -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| His 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| Gly 5 | - | expression tag |
| Ser 6 | - | expression tag |
| Gly 7 | - | expression tag |
| Leu 8 | - | expression tag |
| Asn 9 | - | expression tag |
| Asp 10 | - | expression tag |
| Ile 11 | - | expression tag |
| Phe 12 | - | expression tag |
| Glu 13 | - | expression tag |
| Ala 14 | - | expression tag |
| Gln 15 | - | expression tag |
| Lys 16 | - | expression tag |
| Ile 17 | - | expression tag |
| Glu 18 | - | expression tag |
| Trp 19 | - | expression tag |
| His 20 | - | expression tag |
| Glu 21 | - | expression tag |
| Gly 22 | - | expression tag |
| Ser 23 | - | expression tag |
| Ile 24 | - | expression tag |
| Ile 25 | - | expression tag |
| Asn 26 | - | expression tag |
| Glu 27 | - | expression tag |
| Thr 28 | - | expression tag |
| Ala 29 | - | expression tag |
| Asp 30 | - | expression tag |
| Asp 31 | - | expression tag |
| Ile 32 | - | expression tag |
| Val 33 | - | expression tag |
| Tyr 34 | - | expression tag |
| Arg 35 | - | expression tag |
| Leu 36 | - | expression tag |
| Thr 37 | - | expression tag |
| Val 38 | - | expression tag |
| Ile 39 | - | expression tag |
| Ile 40 | - | expression tag |
| Asp 41 | - | expression tag |
| Asp 42 | - | expression tag |
| Arg 43 | - | expression tag |
| Tyr 44 | - | expression tag |
| Glu 45 | - | expression tag |
| Ser 46 | - | expression tag |
| Leu 47 | - | expression tag |
| Lys 48 | - | expression tag |
| Asn 49 | - | expression tag |
| Leu 50 | - | expression tag |
| Ile 51 | - | expression tag |
| Thr 52 | - | expression tag |
| Leu 53 | - | expression tag |
| Arg 54 | - | expression tag |
| Ala 55 | - | expression tag |
| Asp 56 | - | expression tag |
| Arg 57 | - | expression tag |
| Leu 58 | - | expression tag |
| Glu 59 | - | expression tag |
| Met 60 | - | expression tag |
| Ile 61 | - | expression tag |
| Ile 62 | - | expression tag |
| Asn 63 | - | expression tag |
| Asp 64 | - | expression tag |
| Asn 65 | - | expression tag |
| Val 66 | - | expression tag |
| Ser 67 | - | expression tag |
| Thr 68 | - | expression tag |
| Ile 69 | - | expression tag |
| Leu 70 | - | expression tag |
| Ala 71 | - | expression tag |
| Ser 72 | - | expression tag |
| Gly 73 | - | expression tag |
| Glu 74 | - | expression tag |
| Asn 75 | - | expression tag |
| Leu 76 | - | expression tag |
| Tyr 77 | - | expression tag |
| Phe 78 | - | expression tag |
| Gln 79 | - | expression tag |
| Gly 80 | - | expression tag |
| Ser 81 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 411987.7 | |
| Branched | Number of molecules | 24 |
| Total formula weight | 16347.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 200.4 | |
| All* | Total formula weight | 428535.0 |
