4XRR
 
 | | Crystal structure of cals8 from micromonospora echinospora (P294S mutant) | | 分子名称: | CalS8, GLYCEROL | | 著者 | Michalska, K, Bigelow, L, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R.M, Singh, S, Kharel, M.K, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2015-01-21 | | 公開日 | 2015-02-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural Characterization of CalS8, a TDP-alpha-D-Glucose Dehydrogenase Involved in Calicheamicin Aminodideoxypentose Biosynthesis.
J. Biol. Chem., 290, 2015
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4XSA
 | | Determining the Molecular Basis for Starter Unit Selection During Daunorubicin Biosynthesis | | 分子名称: | Daunorubicin-doxorubicin polyketide synthase | | 著者 | Jackson, D.R, Valentic, T.R, Tsai, S.C, Patel, A, Mohammed, L, Vasilakis, K, Wattana-amorn, P, Long, P.F, Crump, M.P, Crosby, J. | | 登録日 | 2015-01-22 | | 公開日 | 2016-01-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | | 主引用文献 | Determining the Molecular Basis for Starter Unit Selection During Daunorubicin Biosynthesis
To Be Published
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7SX9
 | | T-Plastin-F-actin complex, anti-parallel bundled state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Mei, L, Reynolds, M.J, Alushin, G.M. | | 登録日 | 2021-11-22 | | 公開日 | 2022-08-31 | | 最終更新日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (10 Å) | | 主引用文献 | Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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4XS7
 | | Determining the Molecular Basis for Starter Unit Selection During Daunorubicin Biosynthesis | | 分子名称: | Daunorubicin-doxorubicin polyketide synthase | | 著者 | Jackson, D.R, Valentic, T.R, Tsai, S.C, Patel, A, Mohammed, L, Vasilakis, K, Wattana-amorn, P, Long, P.F, Crump, M.P, Crosby, J. | | 登録日 | 2015-01-22 | | 公開日 | 2016-01-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Determining the Molecular Basis for Starter Unit Selection During Daunorubicin Biosynthesis
To Be Published
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5J0F
 | | Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P4/5 | | 分子名称: | GLYCEROL, Superoxide dismutase [Cu-Zn],OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn] | | 著者 | Wang, H, Lang, L, Logan, D, Danielsson, J, Oliveberg, M. | | 登録日 | 2016-03-28 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Tricking a Protein To Swap Strands.
J. Am. Chem. Soc., 138, 2016
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5ITX
 | | Crystal Structure of Human NEIL1(P2G R242K) bound to duplex DNA containing Thymine Glycol | | 分子名称: | DNA (26-MER), Endonuclease 8-like 1 | | 著者 | Zhu, C, Lu, L, Zhang, J, Yue, Z, Song, J, Zong, S, Liu, M, Stovicek, O, Gao, Y, Yi, C. | | 登録日 | 2016-03-17 | | 公開日 | 2016-07-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Tautomerization-dependent recognition and excision of oxidation damage in base-excision DNA repair
Proc.Natl.Acad.Sci.USA, 113, 2016
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7C02
 | | Crystal structure of dimeric MERS-CoV receptor binding domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Dai, L, Qi, J, Gao, G.F. | | 登録日 | 2020-04-30 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS.
Cell, 182, 2020
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1BLR
 | | NMR SOLUTION STRUCTURE OF HUMAN CELLULAR RETINOIC ACID BINDING PROTEIN-TYPE II, 22 STRUCTURES | | 分子名称: | CELLULAR RETINOIC ACID BINDING PROTEIN-TYPE II | | 著者 | Wang, L, Li, Y, Abilddard, F, Yan, H, Markely, J. | | 登録日 | 1998-07-20 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structure of type II human cellular retinoic acid binding protein: implications for ligand binding.
Biochemistry, 37, 1998
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7SXA
 | | T-Plastin-F-actin complex, pre-bundling intermediate state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Mei, L, Reynolds, M.J, Alushin, G.M. | | 登録日 | 2021-11-22 | | 公開日 | 2022-08-31 | | 最終更新日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (6.87 Å) | | 主引用文献 | Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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4QIL
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7T3F
 | | Development of BRD4 inhibitors as arsenicals antidotes | | 分子名称: | 4-fluoro-3-methyl-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzene-1-sulfonamide, Bromodomain-containing protein 4, GLYCEROL | | 著者 | Wu, M, Yatchang, M, Mathew, B, Zhai, L, Ruiz, P, Bostwick, R, Augelli-Szafran, C.E, Suto, M.J. | | 登録日 | 2021-12-07 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | Development of BRD4 inhibitors as anti-inflammatory agents and antidotes for arsenicals.
Bioorg.Med.Chem.Lett., 64, 2022
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7T3K
 | | Cryo-EM structure of Csy-AcrIF24 dimer | | 分子名称: | AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR type I-F/YPEST-associated protein Csy3, ... | | 著者 | Mukherjee, I.A, Chang, L. | | 登録日 | 2021-12-08 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis of AcrIF24 as an anti-CRISPR protein and transcriptional suppressor.
Nat.Chem.Biol., 18, 2022
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4PYR
 | | Structure of a putative branched-chain amino acid ABC transporter from Chromobacterium violaceum ATCC 12472 | | 分子名称: | GLUTATHIONE, Putative branched-chain amino acid ABC transporter | | 著者 | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Endres, M, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-03-27 | | 公開日 | 2014-04-23 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure of a putative branched-chain amino acid ABC transporter from Chromobacterium violaceum ATCC 12472
To be Published
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7SQK
 | | Cryo-EM structure of the human augmin complex | | 分子名称: | HAUS augmin-like complex subunit 1, HAUS augmin-like complex subunit 2, HAUS augmin-like complex subunit 3, ... | | 著者 | Gabel, C.A, Chang, L. | | 登録日 | 2021-11-05 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (8 Å) | | 主引用文献 | Molecular architecture of the augmin complex.
Nat Commun, 13, 2022
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7T3J
 | | Cryo-EM structure of Csy-AcrIF24 | | 分子名称: | AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR type I-F/YPEST-associated protein Csy3, ... | | 著者 | Mukherjee, I.A, Chang, L. | | 登録日 | 2021-12-08 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis of AcrIF24 as an anti-CRISPR protein and transcriptional suppressor.
Nat.Chem.Biol., 18, 2022
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7TAW
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2DPJ
 | | structure of hPoli with DNA and dTTP | | 分子名称: | 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(EDA)P*GP*GP*GP*TP*CP*CP*T)-3', DNA polymerase iota, ... | | 著者 | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | | 登録日 | 2006-05-12 | | 公開日 | 2006-07-04 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Hoogsteen base pair formation promotes synthesis opposite the 1,N(6)-ethenodeoxyadenosine lesion by human DNA polymerase iota.
Nat.Struct.Mol.Biol., 13, 2006
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7TAX
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7T3L
 | | Cryo-EM structure of Csy-AcrIF24-DNA dimer | | 分子名称: | AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR type I-F/YPEST-associated protein Csy3, ... | | 著者 | Mukherjee, I.A, Chang, L. | | 登録日 | 2021-12-08 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis of AcrIF24 as an anti-CRISPR protein and transcriptional suppressor.
Nat.Chem.Biol., 18, 2022
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4XUG
 | | Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with 2-({[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) inhibitor in the alpha site and ammonium ion in the metal coordination site. | | 分子名称: | 1,2-ETHANEDIOL, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, AMMONIUM ION, ... | | 著者 | Hilario, E, Caulkins, B.G, Young, R.P, Niks, D, Dunn, M.F, Mueller, L.J, Fan, L. | | 登録日 | 2015-01-25 | | 公開日 | 2016-01-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with 2-({[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) inhibitor in the alpha site and ammonium ion in the metal coordination site.
To Be Published
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1BTL
 | | CRYSTAL STRUCTURE OF ESCHERICHIA COLI TEM1 BETA-LACTAMASE AT 1.8 ANGSTROMS RESOLUTION | | 分子名称: | BETA-LACTAMASE TEM1, SULFATE ION | | 著者 | Jelsch, C, Mourey, L, Masson, J.M, Samama, J.P. | | 登録日 | 1993-11-01 | | 公開日 | 1995-01-26 | | 最終更新日 | 2019-08-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of Escherichia coli TEM1 beta-lactamase at 1.8 A resolution.
Proteins, 16, 1993
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4QDX
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4Q31
 | | The crystal structure of cystathione gamma lyase (CalE6) from Micromonospora echinospora | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FORMIC ACID, ... | | 著者 | Tan, K, Bigelow, L, Jedrzejczak, R, Babnigg, G, Bingman, C.A, Yennamalli, R.M, Singh, S, Kharel, M.K, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2014-04-10 | | 公開日 | 2014-05-07 | | 最終更新日 | 2017-03-08 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Structural dynamics of a methionine gamma-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate.
Struct Dyn, 3, 2016
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4QEK
 | | Crystal structure of Antigen 85C-S124A mutant | | 分子名称: | Diacylglycerol acyltransferase/mycolyltransferase Ag85C, SULFATE ION, alpha-D-glucopyranose | | 著者 | Favrot, L, Lajiness, D.H, Ronning, D.R. | | 登録日 | 2014-05-16 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.299 Å) | | 主引用文献 | Inactivation of the Mycobacterium tuberculosis Antigen 85 Complex by Covalent, Allosteric Inhibitors.
J.Biol.Chem., 289, 2014
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2DDY
 | | Solution Structure of Matrilysin (MMP-7) Complexed to Constraint Conformational Sulfonamide Inhibitor | | 分子名称: | (1R)-N,6-DIHYDROXY-7-METHOXY-2-[(4-METHOXYPHENYL)SULFONYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-1-CARBOXAMIDE, CALCIUM ION, Matrilysin, ... | | 著者 | Zheng, X.H, Ou, L. | | 登録日 | 2006-02-06 | | 公開日 | 2007-02-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of Matrilysin (MMP-7) Complexed to Constraint Conformational Sulfonamide Inhibitor
to be published
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