4Q31

The crystal structure of cystathione gamma lyase (CalE6) from Micromonospora echinospora

Summary for 4Q31

• Entry DOI: 10.2210/pdb4q31/pdb
• Descriptor: cystathione gamma lyase CalE6, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: structural genomics, psi-biology, protein structure initiative, midwest center for structural genomics, mcsg, enzyme discovery for natural product biosynthesis, natpro, lyase
• Biological source: Micromonospora echinospora
• Total number of polymer chains: 8
• Total formula weight: 335292.09

Authors

Tan, K.,Bigelow, L.,Jedrzejczak, R.,Babnigg, G.,Bingman, C.A.,Yennamalli, R.M.,Singh, S.,Kharel, M.K.,Thorson, J.S.,Phillips Jr., G.N.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2014-04-10, release date: 2014-05-07, Last modification date: 2017-03-08)

• Primary citation: Cao, H.,Tan, K.,Wang, F.,Bigelow, L.,Yennamalli, R.M.,Jedrzejczak, R.,Babnigg, G.,Bingman, C.A.,Joachimiak, A.,Kharel, M.K.,Singh, S.,Thorson, J.S.,Phillips, G.N.; Structural dynamics of a methionine gamma-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate.; Struct Dyn, 3:034702-034702, 2016; PubMed: 27191010; DOI: 10.1063/1.4948539

Experimental method

X-RAY DIFFRACTION (2.099 Å)