2AYR
 
 | | A SERM Designed for the Treatment of Uterine Leiomyoma with Unique Tissue Specificity for Uterus and Ovaries in Rats | | 分子名称: | 6-(4-METHYLSULFONYL-PHENYL)-5-[4-(2-PIPERIDIN-1-YLETHOXY)PHENOXY]NAPHTHALEN-2-OL, Estrogen receptor | | 著者 | Hummel, C.W, Geiser, A.G, Bryant, H.U, Cohen, I.R, Dally, R.D, Fong, K.C, Frank, S.A, Hinklin, R, Jones, S.A, Lewis, G, McCann, D.J, Shepherd, T.A, Tian, H, Rudman, D.G, Wallace, O.B, Wang, Y, Dodge, J.A. | | 登録日 | 2005-09-07 | | 公開日 | 2005-11-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A selective estrogen receptor modulator designed for the treatment of uterine leiomyoma with unique tissue specificity for uterus and ovaries in rats
J.Med.Chem., 48, 2005
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1MOZ
 | | ADP-ribosylation factor-like 1 (ARL1) from Saccharomyces cerevisiae | | 分子名称: | ADP-ribosylation factor-like protein 1, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Amor, J.C, Horton, J.R, Zhu, X, Wang, Y, Sullards, C, Ringe, D, Cheng, X, Kahn, R.A. | | 登録日 | 2002-09-10 | | 公開日 | 2002-10-09 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | | 主引用文献 | Structures of Yeast ARF2 and ARL1:
DISTINCT ROLES FOR THE N TERMINUS IN THE STRUCTURE
AND FUNCTION OF ARF FAMILY GTPases
J.Biol.Chem., 276, 2001
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6JDV
 | | Crystal structure of Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in catalytic state | | 分子名称: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, MAGNESIUM ION, ... | | 著者 | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | | 登録日 | 2019-02-02 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
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1NA6
 | | Crystal structure of restriction endonuclease EcoRII mutant R88A | | 分子名称: | Restriction endonuclease EcoRII | | 著者 | Zhou, X.E, Wang, Y, Reuter, M, Mucke, M, Kruger, D.H, Meehan, E.J, Chen, L. | | 登録日 | 2002-11-26 | | 公開日 | 2003-12-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of type IIE restriction endonuclease EcoRII reveals an autoinhibition mechanism by a novel effector-binding fold.
J.Mol.Biol., 335, 2004
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6JFU
 | | Crystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM) | | 分子名称: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, non-target strand, ... | | 著者 | Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y. | | 登録日 | 2019-02-12 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
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2B5F
 | | Crystal structure of the spinach aquaporin SoPIP2;1 in an open conformation to 3.9 resolution | | 分子名称: | aquaporin | | 著者 | Tornroth-Horsefield, S, Wang, Y, Hedfalk, K, Johanson, U, Karlsson, M, Tajkhorshid, E, Neutze, R, Kjellbom, P. | | 登録日 | 2005-09-28 | | 公開日 | 2005-12-20 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Structural mechanism of plant aquaporin gating
Nature, 439, 2006
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1PCG
 | | Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions | | 分子名称: | ESTRADIOL, estrogen receptor, peptide inhibitor | | 著者 | Leduc, A.M, Trent, J.O, Wittliff, J.L, Bramlett, K.S, Briggs, S.L, Chirgadze, N.Y, Wang, Y, Burris, T.P, Spatola, A.F. | | 登録日 | 2003-05-16 | | 公開日 | 2003-10-28 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions
Proc.Natl.Acad.Sci.USA, 100, 2003
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1PVZ
 | | Solution Structure of BmP07, A Novel Potassium Channel Blocker from Scorpion Buthus martensi Karsch, 15 structures | | 分子名称: | K+ toxin-like peptide | | 著者 | Wu, H, Zhang, N, Wang, Y, Zhang, Q, Ou, L, Li, M, Hu, G. | | 登録日 | 2003-06-29 | | 公開日 | 2004-05-18 | | 最終更新日 | 2018-06-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of BmKK2, a new potassium channel blocker from the venom of chinese scorpion Buthus martensi Karsch
PROTEINS, 55, 2004
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2CPU
 | | SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT | | 分子名称: | ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION | | 著者 | Brayer, G.D, Sidhu, G, Maurus, R, Rydberg, E.H, Braun, C, Wang, Y, Nguyen, N.T, Overall, C.M, Withers, S.G. | | 登録日 | 1999-06-08 | | 公開日 | 2001-06-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques.
Biochemistry, 39, 2000
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2F0X
 | | Crystal structure and function of human thioesterase superfamily member 2(THEM2) | | 分子名称: | SULFATE ION, Thioesterase superfamily member 2 | | 著者 | Cheng, Z, Song, F, Shan, X, Wang, Y, Wei, Z, Gong, W. | | 登録日 | 2005-11-14 | | 公開日 | 2006-10-10 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of human thioesterase superfamily member 2
Biochem.Biophys.Res.Commun., 349, 2006
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7X63
 | | SARS-CoV-2-Beta-RBD and BD-236-GWP/P-VK antibody complex | | 分子名称: | BD-236 Fab heavy chain, BD-236 Fab light chain, Spike protein S1 | | 著者 | Shi, R, Wang, Y, Wu, Z, Han, X, Yan, J. | | 登録日 | 2022-03-06 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | SARS-CoV-2-Beta-RBD and BD-236-GWP/P-VK antibody complex
To Be Published
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7X66
 | | SARS-CoV-2-Omicron-RBD and BD-236-GWP/P-VK antibody complex | | 分子名称: | BD-236 Fab heavy chain, BD-236 Fab light chain, Spike protein S1 | | 著者 | Shi, R, Wang, Y, Wu, Z, Han, X, Yan, J. | | 登録日 | 2022-03-06 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | SARS-CoV-2-Omicron-RBD and BD-236-GWP/P-VK antibody complex
To Be Published
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7X4Y
 | | Crystal structure of Bacteroides thetaiotaomicron glutamate decarboxylase BTGAD-PLP-GABA complex | | 分子名称: | GAMMA-AMINO-BUTANOIC ACID, Glutamate decarboxylase, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Liu, S, Du, G, Wang, Y, Wen, B, Xin, F. | | 登録日 | 2022-03-03 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple elements under different pH.
Food Chem, 403, 2023
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7X52
 | | Crystal structure of Bacteroides thetaiotaomicron glutamate decarboxylase BTGAD-PLP complex | | 分子名称: | ACETATE ION, Glutamate decarboxylase, MALONATE ION, ... | | 著者 | Liu, S, Du, G, Wang, Y, Wen, B, Xin, F. | | 登録日 | 2022-03-03 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple elements under different pH.
Food Chem, 403, 2023
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7XIL
 | | SARS-CoV-2-Beta-RBD and B38-GWP/P-VK antibody complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, B38 Fab heavy chain, B38 Fab light chain, ... | | 著者 | Shi, R, Wang, Y, Wu, Z, Han, X, Yan, J. | | 登録日 | 2022-04-13 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | SARS-CoV-2-Beta-RBD and B38-GWP/P-VK antibody complex
To Be Published
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7XIK
 | | SARS-CoV-2-Omicron-RBD and B38-GWP/P-VK antibody complex | | 分子名称: | B38 Fab heavy chain, B38 Fab light chain, Spike protein S1 | | 著者 | Shi, R, Wang, Y, Wu, Z, Han, X, Yan, J. | | 登録日 | 2022-04-13 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | SARS-CoV-2-Omicron-RBD and B38-GWP/P-VK antibody complex
To Be Published
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7V8E
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7V8G
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7V8F
 | | Crystal structure of UBE2L3 bound to HOIP RING1 domain. | | 分子名称: | E3 ubiquitin-protein ligase RNF31, Ubiquitin-conjugating enzyme E2 L3, ZINC ION | | 著者 | Liu, J, Wang, Y, Pan, L. | | 登録日 | 2021-08-22 | | 公開日 | 2022-03-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7V8H
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3RJY
 | | Crystal Structure of Hyperthermophilic Endo-beta-1,4-glucanase in complex with substrate | | 分子名称: | Endoglucanase FnCel5A, PHOSPHATE ION, alpha-D-glucopyranose | | 著者 | Zheng, B, Yang, W, Zhao, X, Wang, Y, Lou, Z, Rao, Z, Feng, Y. | | 登録日 | 2011-04-15 | | 公開日 | 2012-02-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of hyperthermophilic Endo-beta-1,4-glucanase: Implications for catalytic mechanism and thermostability.
J.Biol.Chem., 287, 2012
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8JFQ
 | | Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-back Loop | | 分子名称: | 26mer-DNA | | 著者 | Liu, Y, Li, J, Zhang, Y, Wang, Y, Chen, J, Bian, Y, Xia, Y, Yang, M.H, Zheng, K, Wang, K.B, Kong, L.Y. | | 登録日 | 2023-05-18 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-Back Loop.
J.Am.Chem.Soc., 145, 2023
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5WQN
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2PL5
 | | Crystal Structure of Homoserine O-acetyltransferase from Leptospira interrogans | | 分子名称: | GLYCEROL, Homoserine O-acetyltransferase | | 著者 | Liu, L, Wang, M, Wang, Y, Wei, Z, Xu, H, Gong, W. | | 登録日 | 2007-04-19 | | 公開日 | 2007-11-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of homoserine O-acetyltransferase from Leptospira interrogans
Biochem.Biophys.Res.Commun., 363, 2007
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8KDE
 | | Cryo-EM structure of an intermediate-state complex during the process of photosystem II repair | | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | | 著者 | Li, A, Wang, Y, Liu, Z. | | 登録日 | 2023-08-09 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural basis for an early stage of the photosystem II repair cycle in Chlamydomonas reinhardtii.
Nat Commun, 15, 2024
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