3QQI
 
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4KY2
 | | Transthyretin in complex with the fluorescent folding sensor (E)-7-hydroxy-3-(4-hydroxy-3,5-dimethylstyryl)-4-methyl-2H-chromen-2-one | | 分子名称: | 7-hydroxy-3-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]-4-methyl-2H-chromen-2-one, Transthyretin | | 著者 | Connelly, S, Wilson, I.A, Choi, S. | | 登録日 | 2013-05-28 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | | 主引用文献 | Bifunctional coumarin derivatives that inhibit transthyretin amyloidogenesis and serve as fluorescent transthyretin folding sensors.
Chem.Commun.(Camb.), 49, 2013
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3B7E
 | | Neuraminidase of A/Brevig Mission/1/1918 H1N1 strain in complex with zanamivir | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | | 著者 | Xu, X, Zhu, X, Wilson, I.A. | | 登録日 | 2007-10-30 | | 公開日 | 2008-10-07 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structural characterization of the 1918 influenza virus H1N1 neuraminidase
J.Virol., 82, 2008
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6WOQ
 | | Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody HC1AM and non neutralizing antibody E1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... | | 著者 | Tzarum, N, Wilson, I.A, Law, M. | | 登録日 | 2020-04-25 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.667 Å) | | 主引用文献 | An alternate conformation of HCV E2 neutralizing face as an additional vaccine target.
Sci Adv, 6, 2020
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6WCR
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3R08
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3R2X
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3B9K
 | | Crystal structure of CD8alpha-beta in complex with YTS 156.7 FAB | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Heavy chain, Fab Light Chain, ... | | 著者 | Shore, D, Wilson, I.A. | | 登録日 | 2007-11-05 | | 公開日 | 2008-11-11 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The Crystal Structure of CD8 in Complex with YTS156.7.7 Fab and Interaction with Other CD8 Antibodies Define the Binding Mode of CD8 alphabeta to MHC Class I
J.Mol.Biol., 384, 2008
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4I78
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3QHF
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4L1T
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4JY5
 | | Crystal structure of human Fab PGT122, a broadly reactive and potent HIV-1 neutralizing antibody | | 分子名称: | GLYCEROL, PGT122 heavy chain, PGT122 light chain | | 著者 | Julien, J.-P, Diwanji, D.C, Burton, D.R, Wilson, I.A. | | 登録日 | 2013-03-29 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
Plos Pathog., 9, 2013
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3QHZ
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3E6J
 | | Crystal Structure of Variable Lymphocyte Receptor (VLR) RBC36 in Complex with H-trisaccharide | | 分子名称: | GLYCEROL, SULFATE ION, Variable lymphocyte receptor diversity region, ... | | 著者 | Han, B.W, Herrin, B.R, Cooper, M.D, Wilson, I.A. | | 登録日 | 2008-08-15 | | 公開日 | 2008-10-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Antigen recognition by variable lymphocyte receptors.
Science, 321, 2008
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3ESP
 | | Human transthyretin (TTR) complexed with N-(3,5-Dibromo-4-hydroxyphenyl)-3,5-dimethyl-4-hydroxybenzamide | | 分子名称: | N-(3,5-dibromo-4-hydroxyphenyl)-4-hydroxy-3,5-dimethylbenzamide, Transthyretin | | 著者 | Connelly, S, Wilson, I.A. | | 登録日 | 2008-10-06 | | 公開日 | 2009-04-07 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | Toward optimization of the second aryl substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
J.Med.Chem., 52, 2009
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3O2V
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3OAY
 | | A non-self sugar mimic of the HIV glycan shield shows enhanced antigenicity | | 分子名称: | Fab 2G12, heavy chain, light chain, ... | | 著者 | Doores, K.J, Fulton, Z, Hong, V, Patel, M.K, Scanlan, C.N, Wormald, M.R, Finn, M.G, Burton, D.R, Wilson, I.A, Davis, B.G. | | 登録日 | 2010-08-05 | | 公開日 | 2011-01-12 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3O2W
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4K3E
 | | Crystal structure of bovine antibody BLV5B8 with ultralong CDR H3 | | 分子名称: | BOVINE ANTIBODY WITH ULTRALONG CDR H3, HEAVY CHAIN, LIGHT CHAIN, ... | | 著者 | Ekiert, D.C, Wang, F, Wilson, I.A. | | 登録日 | 2013-04-10 | | 公開日 | 2013-06-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Reshaping antibody diversity.
Cell(Cambridge,Mass.), 153, 2013
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4K3X
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4L1S
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3CFD
 | | Purple-fluorescent antibody EP2-25C10 in complex with its stilbene hapten | | 分子名称: | 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID, GLYCEROL, PURPLE-FLUORESCENT ANTIBODY EP2-25C10-IGG2B HEAVY CHAIN, ... | | 著者 | Debler, E.W, Heine, A, Wilson, I.A. | | 登録日 | 2008-03-03 | | 公開日 | 2008-03-18 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.
Science, 319, 2008
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3CN2
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3CFC
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4LG2
 | | Crystal structure of Reston Ebola virus VP35 RNA binding domain bound to 12-bp dsRNA | | 分子名称: | Polymerase cofactor, dsRNA | | 著者 | Bale, S, Julien, J.-P, Bornholdt, Z.A, Krois, A.S, Wilson, I.A, Saphire, E.O. | | 登録日 | 2013-06-27 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Ebolavirus VP35 coats the backbone of double-stranded RNA for interferon antagonism.
J.Virol., 87, 2013
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