4L1T

Transthyretin in complex with (E)-3-(dimethylamino)-5-(4-hydroxy-3,5-dimethylstyryl)benzoic acid

Summary for 4L1T

• Entry DOI: 10.2210/pdb4l1t/pdb
• Related: 3CN0 3CN1
• Descriptor: Transthyretin, 3-(dimethylamino)-5-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzoic acid (3 entities in total)
• Functional Keywords: hormone transport protein, thyroxine, retinol, transport protein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P02766
• Total number of polymer chains: 2
• Total formula weight: 28177.47

Authors

Connelly, S.,Wilson, I.A. (deposition date: 2013-06-03, release date: 2013-10-02, Last modification date: 2023-09-20)

• Primary citation: Baranczak, A.,Connelly, S.,Liu, Y.,Choi, S.,Grimster, N.P.,Powers, E.T.,Wilson, I.A.,Kelly, J.W.; Fluorogenic small molecules requiring reaction with a specific protein to create a fluorescent conjugate for biological imaging-what we know and what we need to learn.; Biopolymers, 101:484-495, 2014; PubMed: 24105107; DOI: 10.1002/bip.22407

Experimental method

X-RAY DIFFRACTION (1.16 Å)