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3CN1

Human transthyretin (TTR) in complex with 3,5-Dibromo-4-hydroxystilbene

Summary for 3CN1
Entry DOI10.2210/pdb3cn1/pdb
Related2QGB 3CN0 3CN2 3CN3 3CN4
DescriptorTransthyretin, 2,6-dibromo-4-[(E)-2-phenylethenyl]phenol (3 entities in total)
Functional Keywordstransthyretin, tetramer, hormone, transport protein
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P02766
Total number of polymer chains2
Total formula weight28262.79
Authors
Connelly, S.,Wilson, I.A. (deposition date: 2008-03-24, release date: 2008-10-28, Last modification date: 2024-02-21)
Primary citationJohnson, S.M.,Connelly, S.,Wilson, I.A.,Kelly, J.W.
Toward optimization of the linker substructure common to transthyretin amyloidogenesis inhibitors using biochemical and structural studies.
J.Med.Chem., 51:6348-6358, 2008
Cited by
PubMed: 18811132
DOI: 10.1021/jm800435s
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.52 Å)
Structure validation

217705

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