3B9K

Crystal structure of CD8alpha-beta in complex with YTS 156.7 FAB

Summary for 3B9K

Entry DOI	10.2210/pdb3b9k/pdb
Descriptor	Fab Light Chain, Fab Heavy chain, T-cell surface glycoprotein CD8 alpha chain, ... (6 entities in total)
Functional Keywords	immunoglobulin domain, v-set, igsf dimer, glycoprotein, immune response, membrane, transmembrane, immune system
Biological source	Mus musculus (mouse) More
Cellular location	Cell membrane ; Single-pass type I membrane protein : P01731 Membrane ; Single-pass type I membrane protein: P10300
Total number of polymer chains	8
Total formula weight	150817.30
Authors	Shore, D.,Wilson, I.A. (deposition date: 2007-11-05, release date: 2008-11-11, Last modification date: 2020-07-29)
Primary citation	Shore, D.A.,Issafras, H.,Landais, E.,Teyton, L.,Wilson, I.A. The Crystal Structure of CD8 in Complex with YTS156.7.7 Fab and Interaction with Other CD8 Antibodies Define the Binding Mode of CD8 alphabeta to MHC Class I J.Mol.Biol., 384:1190-1202, 2008 Cited by PubMed: 18929574 DOI: 10.1016/j.jmb.2008.09.069 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation