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8CWM
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BU of 8cwm by Molmil
Cryo-EM structure of the supercoiled S. islandicus REY15A archaeal flagellar filament
分子名称: Flagellin
著者Kreutzberger, M.A.B, Liu, J, Krupovic, M, Egelman, E.H.
登録日2022-05-19
公開日2022-09-07
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Convergent evolution in the supercoiling of prokaryotic flagellar filaments.
Cell, 185, 2022
7FI9
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BU of 7fi9 by Molmil
Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
分子名称: GLYCEROL, MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein
著者Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J.
登録日2021-07-30
公開日2022-08-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
to be published
7FI7
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BU of 7fi7 by Molmil
Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
分子名称: MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein
著者Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J.
登録日2021-07-30
公開日2022-08-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
to be published
7FI8
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BU of 7fi8 by Molmil
Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
分子名称: MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein
著者Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J.
登録日2021-07-30
公開日2022-08-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
to be published
7FI6
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BU of 7fi6 by Molmil
Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
分子名称: MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein
著者Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J.
登録日2021-07-30
公開日2022-08-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
to be published
7FI5
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BU of 7fi5 by Molmil
Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
分子名称: GLYCEROL, MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein
著者Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J.
登録日2021-07-30
公開日2022-08-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
to be published
6JUI
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BU of 6jui by Molmil
The atypical Myb-like protein Cdc5 contains two distinct nucleic acid-binding surfaces
分子名称: Pre-mRNA-splicing factor CEF1
著者Wang, C, Li, G, Li, M, Yang, J, Liu, J.
登録日2019-04-14
公開日2020-02-19
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Two distinct nucleic acid binding surfaces of Cdc5 regulate development.
Biochem.J., 476, 2019
7DAC
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BU of 7dac by Molmil
Human RIPK3 amyloid fibril revealed by solid-state NMR
分子名称: Receptor-interacting serine/threonine-protein kinase 3
著者Wu, X.L, Zhang, J, Dong, X.Q, Liu, J, Li, B, Hu, H, Wang, J, Wang, H.Y, Lu, J.X.
登録日2020-10-16
公開日2021-04-28
最終更新日2024-05-01
実験手法SOLID-STATE NMR
主引用文献The structure of a minimum amyloid fibril core formed by necroptosis-mediating RHIM of human RIPK3.
Proc.Natl.Acad.Sci.USA, 118, 2021
8IFO
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BU of 8ifo by Molmil
Crystal structure of estrogen related receptor-gamma DNA binding domain complexed with Pla2g12b promoter
分子名称: DNA (5'-D(*GP*AP*GP*GP*AP*CP*AP*AP*AP*GP*GP*TP*GP*AP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*TP*CP*AP*CP*CP*TP*TP*TP*GP*TP*CP*CP*TP*C)-3'), Estrogen-related receptor gamma, ...
著者Xu, T, Zhen, X, Liu, J.
登録日2023-02-19
公開日2023-03-29
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献ERR gamma-DBD undergoes dimerization and conformational rearrangement upon binding to the downstream site of the DR1 element.
Biochem.Biophys.Res.Commun., 656, 2023
7VF5
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BU of 7vf5 by Molmil
Human m6A-METTL associated complex (WTAP, VIRMA, and HAKAI)
分子名称: Pre-mRNA-splicing regulator WTAP, Protein virilizer homolog
著者Su, S, Li, S, Deng, T, Gao, M, Yin, Y, Wu, B, Peng, C, Liu, J, Ma, J, Zhang, K.
登録日2021-09-10
公開日2022-09-14
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM structures of human m6A writer complexes.
Cell Res., 32, 2022
7VF2
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BU of 7vf2 by Molmil
Human m6A-METTL associated complex (WTAP, VIRMA, ZC3H13, and HAKAI)
分子名称: Pre-mRNA-splicing regulator WTAP, Protein virilizer homolog, Zinc finger CCCH domain-containing protein 13
著者Su, S, Li, S, Deng, T, Gao, M, Yin, Y, Wu, B, Peng, C, Liu, J, Ma, J, Zhang, K.
登録日2021-09-10
公開日2022-09-14
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM structures of human m6A writer complexes.
Cell Res., 32, 2022
5ZG9
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BU of 5zg9 by Molmil
Crystal structure of MoSub1-ssDNA complex in phosphate buffer
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*G)-3'), MoSub1, PHOSPHATE ION
著者Zhao, Y, Huang, J, Liu, H, Yi, L, Wang, S, Zhang, X, Liu, J.
登録日2018-03-08
公開日2019-03-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献The effect of phosphate ion on the ssDNA binding mode of MoSub1, a Sub1/PC4 homolog from rice blast fungus.
Proteins, 87, 2019
4QY0
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BU of 4qy0 by Molmil
Structure of H10 from human-infecting H10N8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin
著者Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
登録日2014-07-23
公開日2015-01-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
2OKA
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BU of 2oka by Molmil
Crystal structure of Q9HYQ7_PSEAE from Pseudomonas aeruginosa. Northeast Structural Genomics Consortium target PaR82
分子名称: Hypothetical protein
著者Benach, J, Neely, H, Seetharaman, J, Chen, X.C, Fang, Y, Cunningham, K, Owens, L, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2007-01-16
公開日2007-01-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of Q9HYQ7_PSEAE from Pseudomonas aeruginosa
To be Published
2O5A
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BU of 2o5a by Molmil
Crystal structure of Q9KD89 from Bacillus halodurans. Northeast Structural Genomics target BhR21
分子名称: BH1328 protein, MANGANESE (II) ION, SULFATE ION
著者Benach, J, Su, M, Seetharaman, J, Ho, C.H, Janjua, H, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2006-12-05
公開日2006-12-19
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of Q9KD89 from Bacillus halodurans. Northeast Structural Genomics target BhR21
To be Published
2OAS
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BU of 2oas by Molmil
Crystal Structure of 4-hydroxybutyrate coenzyme A transferase (AtoA) in complex with CoA from Shewanella oneidensis, Northeast Structural Genomics Target SoR119.
分子名称: 4-hydroxybutyrate coenzyme A transferase, COENZYME A
著者Forouhar, F, Neely, H, Hussain, M, Benach, J, Seetharaman, J, Cunningham, K, Ma, L.C, Owen, L, Fang, Y, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2006-12-17
公開日2007-01-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of 4-hydroxybutyrate coenzyme A transferase (AtoA) from Shewanella oneidensis in complex with CoA, Northeast Structural Genomics Target SoR119.
To be Published
5VSC
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BU of 5vsc by Molmil
Structure of human G9a SET-domain (EHMT2) in complex with inhibitor 13
分子名称: 6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)-N~2~-propylquinazoline-2,4-diamine, Histone-lysine N-methyltransferase EHMT2, S-ADENOSYLMETHIONINE, ...
著者Babault, N, Xiong, Y, Liu, J, Jin, J.
登録日2017-05-11
公開日2017-07-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure-activity relationship studies of G9a-like protein (GLP) inhibitors.
Bioorg. Med. Chem., 25, 2017
5VSF
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BU of 5vsf by Molmil
Structure of human GLP SET-domain (EHMT1) in complex with inhibitor 17
分子名称: 1,4-DIETHYLENE DIOXIDE, GLYCEROL, Histone-lysine N-methyltransferase EHMT1, ...
著者Babault, N, Xiong, Y, Liu, J, Jin, J.
登録日2017-05-11
公開日2017-07-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-activity relationship studies of G9a-like protein (GLP) inhibitors.
Bioorg. Med. Chem., 25, 2017
5VSE
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BU of 5vse by Molmil
Structure of human G9a SET-domain (EHMT2) in complex with inhibitor 17: N~2~-cyclopentyl-6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine
分子名称: Histone-lysine N-methyltransferase EHMT2, N~2~-cyclopentyl-6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine, S-ADENOSYLMETHIONINE, ...
著者Babault, N, Xiong, Y, Liu, J, Jin, J.
登録日2017-05-11
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure-activity relationship studies of G9a-like protein (GLP) inhibitors.
Bioorg. Med. Chem., 25, 2017
5VSD
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BU of 5vsd by Molmil
Structure of human GLP SET-domain (EHMT1) in complex with inhibitor 13
分子名称: 1,4-DIETHYLENE DIOXIDE, 6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)-N~2~-propylquinazoline-2,4-diamine, GLYCEROL, ...
著者Babault, N, Xiong, Y, Liu, J, Jin, J.
登録日2017-05-11
公開日2017-07-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure-activity relationship studies of G9a-like protein (GLP) inhibitors.
Bioorg. Med. Chem., 25, 2017
5EP6
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BU of 5ep6 by Molmil
The crystal structure of NAP1 in complex with TBK1
分子名称: 5-azacytidine-induced protein 2, GLYCEROL, Serine/threonine-protein kinase TBK1
著者Li, F, Xie, X, Liu, J, Pan, L.
登録日2015-11-11
公開日2016-09-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins.
Nat Commun, 7, 2016
5EOF
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BU of 5eof by Molmil
Crystal structure of OPTN NTD and TBK1 CTD complex
分子名称: Optineurin, Serine/threonine-protein kinase TBK1
著者Li, F, Xie, X, Liu, J, Pan, L.
登録日2015-11-10
公開日2016-09-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins.
Nat Commun, 7, 2016
5WZT
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BU of 5wzt by Molmil
Crystal structure of human secreted phospholipase A2 group IIE with Compound 14
分子名称: 2-[1-[(3-bromophenyl)methyl]-2-methyl-3-oxamoyl-indol-4-yl]oxyethanoic acid, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者Hou, S, Xu, J, Xu, T, Liu, J.
登録日2017-01-18
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE
Sci Rep, 7, 2017
8GDX
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BU of 8gdx by Molmil
Crystal structure of JADE1 PZP domain
分子名称: GLYCEROL, Protein Jade-1, ZINC ION
著者Klein, B.J, Liu, J, Kutateladze, T.G.
登録日2023-03-06
公開日2024-03-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 2024
8GE0
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BU of 8ge0 by Molmil
Crystal structure of JADE1 PZP domain in complex with Histone H3
分子名称: Histone H3.1,Protein Jade-1, ZINC ION
著者Klein, B.J, Liu, J, Kutateladze, T.G.
登録日2023-03-06
公開日2024-03-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 2024

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