6PAF
 
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6PER
 | | Crystal Structure of Ligand-Free iSeroSnFR | | 分子名称: | 1,2-ETHANEDIOL, iSeroSnFR, a soluble, ... | | 著者 | Hartanto, S, Tian, L, Fisher, A.J. | | 登録日 | 2019-06-20 | | 公開日 | 2020-06-24 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning.
Cell, 183, 2020
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7FC0
 | | Reconstitution of MbnABC complex from Rugamonas rubra ATCC-43154 (GroupIII) | | 分子名称: | FE (III) ION, Methanobactin biosynthesis cassette protein MbnB, Methanobactin biosynthesis cassette protein MbnC, ... | | 著者 | Chao, D, Zhaolin, L, Shoujie, L, Li, Z, Dan, Z, Ying, J, Wei, C. | | 登録日 | 2021-07-13 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.643 Å) | | 主引用文献 | Crystal structure and catalytic mechanism of the MbnBC holoenzyme required for methanobactin biosynthesis.
Cell Res., 32, 2022
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6PEO
 | | Cryo-EM structure of alpha-synuclein H50Q Narrow Fibril | | 分子名称: | Alpha-synuclein | | 著者 | Boyer, D.R, Li, B, Sawaya, M.R, Jiang, L, Eisenberg, D.S. | | 登録日 | 2019-06-20 | | 公開日 | 2019-11-27 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structures of fibrils formed by alpha-synuclein hereditary disease mutant H50Q reveal new polymorphs.
Nat.Struct.Mol.Biol., 26, 2019
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3WWD
 | | The complex of pOPH_S172C with DMSO | | 分子名称: | CITRIC ACID, DIMETHYL SULFOXIDE, Oxidized polyvinyl alcohol hydrolase | | 著者 | Yang, Y, Ko, T.P, Li, J.H, Liu, L, Huang, C.H, Chen, J, Guo, R.T, Du, G.C. | | 登録日 | 2014-06-17 | | 公開日 | 2015-04-29 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Roles of tryptophan residue and disulfide bond in the variable lid region of oxidized polyvinyl alcohol hydrolase
Biochem.Biophys.Res.Commun., 452, 2014
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3WWC
 | | The complex of pOPH_S172A of pNPB | | 分子名称: | CITRIC ACID, Oxidized polyvinyl alcohol hydrolase, butanoic acid | | 著者 | Yang, Y, Ko, T.P, Li, J.H, Liu, L, Huang, C.H, Chen, J, Guo, R.T, Du, G.C. | | 登録日 | 2014-06-17 | | 公開日 | 2015-04-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Roles of tryptophan residue and disulfide bond in the variable lid region of oxidized polyvinyl alcohol hydrolase
Biochem.Biophys.Res.Commun., 452, 2014
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6PLJ
 | | A nucleotidyl transferase from Methanothermobacter thermautotroptrophicus (Mth528) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ... | | 著者 | Carbone, V, Schofield, L, Sutherland-Smith, A, Ronimus, R. | | 登録日 | 2019-07-01 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | A nucleotidyl transferase from Methanothermobacter thermautotroptrophicus (Mth528)
To Be Published
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8DYS
 | | Crystal structure of human Eukaryotic translation initiation factor 2A (eIF2A) | | 分子名称: | 1,2-ETHANEDIOL, Eukaryotic translation initiation factor 2A, GLYCEROL, ... | | 著者 | Righetto, G.L, Zeng, H, Dong, A, Li, Y, Hutchinson, A, Seitova, A, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | | 登録日 | 2022-08-05 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of human Eukaryotic translation initiation factor 2A (eIF2A)
To Be Published
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8E4R
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8E4J
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5YLE
 | | MCR-1 complex with ethanolamine (ETA) | | 分子名称: | ETHANOLAMINE, Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION | | 著者 | Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L. | | 登録日 | 2017-10-17 | | 公開日 | 2017-11-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
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3WZF
 | | Crystal structure of human cytoplasmic aspartate aminotransferase | | 分子名称: | Aspartate aminotransferase, cytoplasmic | | 著者 | Jiang, X, Chang, H, Zhou, Y, Chen, L, Yang, Q. | | 登録日 | 2014-09-24 | | 公開日 | 2015-10-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.991 Å) | | 主引用文献 | Recombinant expression, purification and Preliminary crystallographic studies of human cytoplasmic aspartate aminotransferase
To be Published
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8AU4
 | | Structural insights reveal a heterotetramer between oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator | | 分子名称: | Ral guanine nucleotide dissociation stimulator-like 2 | | 著者 | Tariq, M, Ikeya, T, Togashi, N, Fairall, L, Alejo, C.B, Kamei, S, Alonso, B.R, Campillo, M.A.M, Hudson, A, Ito, Y, Schwabe, J, Dominguez, C, Tanaka, K. | | 登録日 | 2022-08-25 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insights into the complex of oncogenic KRas4B G12V and Rgl2, a RalA/B activator.
Life Sci Alliance, 7, 2024
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6PDW
 | | Msp1-substrate complex in closed conformation | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | 著者 | Wang, L, Myasnikov, A, Pan, X, Walter, P. | | 登録日 | 2019-06-19 | | 公開日 | 2020-02-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction.
Elife, 9, 2020
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6PQQ
 | | Cryo-EM structure of human TRPA1 C621S mutant in the apo state | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Transient receptor potential cation channel subfamily A member 1, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | 著者 | Suo, Y, Wang, Z, Zubcevic, L, Hsu, A.L, He, Q, Borgnia, M.J, Ji, R.-R, Lee, S.-Y. | | 登録日 | 2019-07-09 | | 公開日 | 2020-01-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | | 主引用文献 | Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.
Neuron, 105, 2020
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3ZLP
 | | Crystal structure of Schistosoma mansoni Peroxiredoxin 1 C48P mutant form with four decamers in the asymmetric unit | | 分子名称: | THIOREDOXIN PEROXIDASE | | 著者 | Saccoccia, F, Angelucci, F, Ardini, M, Boumis, G, Brunori, M, DiLeandro, L, Ippoliti, R, Miele, A.E, Natoli, G, Scotti, S, Bellelli, A. | | 登録日 | 2013-02-04 | | 公開日 | 2013-09-11 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.515 Å) | | 主引用文献 | Switching between the Alternative Structures and Functions of a 2-Cys Peroxiredoxin, by Site-Directed Mutagenesis
J.Mol.Biol., 425, 2013
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3ZRS
 | | X-ray crystal structure of a KirBac potassium channel highlights a mechanism of channel opening at the bundle-crossing gate. | | 分子名称: | ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10, CHLORIDE ION, POTASSIUM ION | | 著者 | Bavro, V.N, De Zorzi, R, Schmidt, M.R, Muniz, J.R.C, Zubcevic, L, Sansom, M.S.P, Venien-Bryan, C, Tucker, S.J. | | 登録日 | 2011-06-17 | | 公開日 | 2012-01-11 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structure of a Kirbac Potassium Channel with an Open Bundle Crossing Indicates a Mechanism of Channel Gating
Nat.Struct.Mol.Biol., 19, 2012
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8DV6
 | | Zika virus envelope protein structure in complex with a potent Human mAb | | 分子名称: | Envelope protein E, mAb Fab Heavy Chain, mAb Fab Light Chain | | 著者 | Cameron, A, Puhl, A.C, deSilva, A.M, Premkumar, L. | | 登録日 | 2022-07-28 | | 公開日 | 2023-01-04 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | | 主引用文献 | Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus.
Plos Pathog., 19, 2023
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6PQO
 | | Cryo-EM structure of the human TRPA1 ion channel in complex with the covalent agonist JT010 | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloro-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-N-(3-methoxypropyl)acetamide, ... | | 著者 | Suo, Y, Wang, Z, Zubcevic, L, Hsu, A.L, He, Q, Borgnia, M.J, Ji, R.-R, Lee, S.-Y. | | 登録日 | 2019-07-09 | | 公開日 | 2020-01-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.
Neuron, 105, 2020
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6PNV
 | | 1.42 Angstrom Resolution Crystal Structure of Translocation Protein TolB from Salmonella enterica | | 分子名称: | POTASSIUM ION, SODIUM ION, Tol-Pal system protein TolB | | 著者 | Minasov, G, Shuvalova, L, Dubrovska, I, Kiryukhina, O, Endres, M, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2019-07-03 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | 1.42 Angstrom Resolution Crystal Structure of Translocation Protein TolB from Salmonella enterica
To Be Published
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8E3I
 | | CRYO-EM STRUCTURE OF the human MPSF IN COMPLEX WITH THE AUUAAA poly(A) signal | | 分子名称: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*CP*AP*UP*UP*AP*AP*AP*CP*AP*AP*C)-3'), ... | | 著者 | Gutierrez, P.A, Wei, J, Sun, Y, Tong, L. | | 登録日 | 2022-08-17 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | | 主引用文献 | Molecular basis for the recognition of the AUUAAA polyadenylation signal by mPSF.
Rna, 28, 2022
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8E1W
 | | Neutron crystal structure of Panus similis AA9A at room temperature | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, COPPER (II) ION, ... | | 著者 | Meilleur, F, Tandrup, T, Lo Leggio, L. | | 登録日 | 2022-08-11 | | 公開日 | 2023-01-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | NEUTRON DIFFRACTION (2.1 Å), X-RAY DIFFRACTION | | 主引用文献 | Joint X-ray/neutron structure of Lentinus similis AA9_A at room temperature.
Acta Crystallogr.,Sect.F, 79, 2023
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8EEQ
 | | CryoEM structures of bAE1 captured in multiple states. | | 分子名称: | Anion exchange protein | | 著者 | Zhekova, H.R, Wang, W.G, Jiang, J.S, Tsirulnikov, K, Muhammad-Khan, G.H, Azimov, R, Abuladze, N, Kao, L, Newman, D, Noskov, S.Y, Tieleman, P, Zhou, Z.H, Pushkin, A, Kurtz, I. | | 登録日 | 2022-09-07 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | | 主引用文献 | CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations.
Commun Biol, 5, 2022
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8E3Q
 | | CRYO-EM STRUCTURE OF the human MPSF | | 分子名称: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, ZINC ION, ... | | 著者 | Gutierrez, P.A, Wei, J, Sun, Y, Tong, L. | | 登録日 | 2022-08-17 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | | 主引用文献 | Molecular basis for the recognition of the AUUAAA polyadenylation signal by mPSF.
Rna, 28, 2022
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6PO4
 | | 2.1 Angstrom Resolution Crystal Structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN) from Haemophilus influenzae PittII. | | 分子名称: | 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE, ... | | 著者 | Minasov, G, Shuvalova, L, Cardona-Correa, A, Dubrovska, I, Grimshaw, S, Kwon, K, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2019-07-03 | | 公開日 | 2019-07-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | 2.1 Angstrom Resolution Crystal Structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN) from Haemophilus influenzae PittII.
To Be Published
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