2QJY
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6I5D
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![BU of 6i5d by Molmil](/molmil-images/mine/6i5d) | Crystal structure of an OXA-48 beta-lactamase synthetic mutant | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ... | 著者 | Zavala, A, Retailleau, P, Dabos, L, Naas, T, Iorga, B. | 登録日 | 2018-11-13 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Substrate specificity of an OXA-48 beta-lactamase synthetic mutant To be published
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6IBR
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![BU of 6ibr by Molmil](/molmil-images/mine/6ibr) | Crystal structure of human alpha-galactosidase A in complex with alpha-galactose configured cyclophellitol epoxide LWA481 | 分子名称: | (2~{R},3~{S},4~{S},5~{R},6~{S})-5-(hydroxymethyl)-7-oxabicyclo[4.1.0]heptane-2,3,4-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Rowland, R.J, Wu, L, Davies, G.J. | 登録日 | 2018-11-30 | 公開日 | 2019-10-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Alpha-d-Gal-cyclophellitol cyclosulfamidate is a Michaelis complex analog that stabilizes therapeutic lysosomal alpha-galactosidase A in Fabry disease Chem Sci, 2019
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6IBT
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![BU of 6ibt by Molmil](/molmil-images/mine/6ibt) | Crystal structure of human alpha-galactosidase A in complex with alpha-galactose configured cyclophellitol aziridine ME737 | 分子名称: | (1~{S},2~{S},3~{S},4~{S},5~{R},6~{S})-5-(hydroxymethyl)-7-azabicyclo[4.1.0]heptane-2,3,4-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Rowland, R.J, Wu, L, Davies, G.J. | 登録日 | 2018-11-30 | 公開日 | 2019-10-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Alpha-d-Gal-cyclophellitol cyclosulfamidate is a Michaelis complex analog that stabilizes therapeutic lysosomal alpha-galactosidase A in Fabry disease Chem Sci, 2019
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6IFU
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![BU of 6ifu by Molmil](/molmil-images/mine/6ifu) | Cryo-EM structure of type III-A Csm-CTR2-dsDNA complex | 分子名称: | CTR2, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | 登録日 | 2018-09-21 | 公開日 | 2018-12-12 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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6IFR
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![BU of 6ifr by Molmil](/molmil-images/mine/6ifr) | Type III-A Csm complex, Cryo-EM structure of Csm-NTR, ATP bound | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Type III-A CRISPR-associated RAMP protein Csm3, ... | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | 登録日 | 2018-09-21 | 公開日 | 2018-12-12 | 最終更新日 | 2019-01-23 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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6IFK
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![BU of 6ifk by Molmil](/molmil-images/mine/6ifk) | Cryo-EM structure of type III-A Csm-CTR1 complex, AMPPNP bound | 分子名称: | CTR1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | 登録日 | 2018-09-20 | 公開日 | 2018-12-12 | 最終更新日 | 2019-01-23 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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6IFL
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![BU of 6ifl by Molmil](/molmil-images/mine/6ifl) | Cryo-EM structure of type III-A Csm-NTR complex | 分子名称: | NTR, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | 登録日 | 2018-09-20 | 公開日 | 2018-12-12 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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1WQ1
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![BU of 1wq1 by Molmil](/molmil-images/mine/1wq1) | RAS-RASGAP COMPLEX | 分子名称: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, H-RAS, ... | 著者 | Scheffzek, K, Ahmadian, M.R, Kabsch, W, Wiesmueller, L, Lautwein, A, Schmitz, F, Wittinghofer, A. | 登録日 | 1997-07-03 | 公開日 | 1998-07-15 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants. Science, 277, 1997
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6IUF
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![BU of 6iuf by Molmil](/molmil-images/mine/6iuf) | Crystal structure of Anti-CRISPR protein AcrVA5 | 分子名称: | ACETYL COENZYME *A, GLYCEROL, protein-a | 著者 | Dong, L, Guan, X, Zhu, Y, Huang, Z. | 登録日 | 2018-11-28 | 公開日 | 2019-04-10 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.052 Å) | 主引用文献 | An anti-CRISPR protein disables type V Cas12a by acetylation. Nat. Struct. Mol. Biol., 26, 2019
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6J71
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![BU of 6j71 by Molmil](/molmil-images/mine/6j71) | HuA21-scFv in complex with the extracellular domain(ECD) of HER2 | 分子名称: | Receptor tyrosine-protein kinase erbB-2, anti-HER2 humanized antibody HuA21, beta-D-mannopyranose, ... | 著者 | Wang, Z, Guo, G, Cheng, B, Zhu, Z, Niu, L, Zhang, H. | 登録日 | 2019-01-16 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.918 Å) | 主引用文献 | Structural insight into a matured humanized monoclonal antibody HuA21 against HER2-overexpressing cancer cells. Acta Crystallogr D Struct Biol, 75, 2019
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1WVB
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![BU of 1wvb by Molmil](/molmil-images/mine/1wvb) | Crystal structure of human arginase I: the mutant E256Q | 分子名称: | Arginase 1, MANGANESE (II) ION, S-2-(BORONOETHYL)-L-CYSTEINE | 著者 | Di Costanzo, L, Guadalupe, S, Mora, A, Centeno, F, Christianson, D.W. | 登録日 | 2004-12-14 | 公開日 | 2005-09-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of human arginase I: the mutant E256Q To be Published
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4BZ0
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![BU of 4bz0 by Molmil](/molmil-images/mine/4bz0) | Structural characterization using Sulfur-SAD of the cytoplasmic domain of Burkholderia pseudomallei PilO2Bp, an actin-like protein component of a Type IVb R64-derivative pilus machinery. | 分子名称: | POTASSIUM ION, PUTATIVE TYPE IV PILUS BIOSYNTHESIS PROTEIN | 著者 | Lassaux, P, Manjasetty, B.A, Conchillo-Sole, O, Yero, D, Gourlay, L, Perletti, L, Daura, X, Belrhali, H, Bolognesi, M. | 登録日 | 2013-07-22 | 公開日 | 2014-04-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Redefining the Pf06864 Pfam Family Based on Burkholderia Pseudomallei Pilo2BP S-Sad Crystal Structure. Plos One, 9, 2014
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6JCX
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6JBH
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![BU of 6jbh by Molmil](/molmil-images/mine/6jbh) | Cryo-EM structure and transport mechanism of a wall teichoic acid ABC transporter | 分子名称: | TarG, TarH | 著者 | Chen, L, Hou, W.T, Fan, T, Li, Y.H, Liu, B.H, Jiang, Y.L, Sun, L.F, Chen, Y, Zhou, C.Z. | 登録日 | 2019-01-25 | 公開日 | 2020-03-04 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | 主引用文献 | Cryo-electron Microscopy Structure and Transport Mechanism of a Wall Teichoic Acid ABC Transporter. Mbio, 11, 2020
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6JBJ
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![BU of 6jbj by Molmil](/molmil-images/mine/6jbj) | Cryo-EM structure of human lysosomal cobalamin exporter ABCD4 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 4 | 著者 | Xu, D, Feng, Z, Hou, W.T, Jiang, Y.L, Wang, L, Sun, L.F, Zhou, C.Z, Chen, Y. | 登録日 | 2019-01-25 | 公開日 | 2019-09-11 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM structure of human lysosomal cobalamin exporter ABCD4. Cell Res., 29, 2019
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1WNO
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![BU of 1wno by Molmil](/molmil-images/mine/1wno) | Crystal structure of a native chitinase from Aspergillus fumigatus YJ-407 | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase, ... | 著者 | Hu, H, Wang, G, Yang, H, Zhou, J, Mo, L, Yang, K, Jin, C, Jin, C, Rao, Z. | 登録日 | 2004-08-07 | 公開日 | 2005-03-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of a native chitinase from Aspergillus fumigatus YJ-407 To be Published
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7OFQ
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3TG5
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![BU of 3tg5 by Molmil](/molmil-images/mine/3tg5) | Structure of SMYD2 in complex with p53 and SAH | 分子名称: | Cellular tumor antigen p53, GLYCEROL, N-lysine methyltransferase SMYD2, ... | 著者 | Zhao, K, Wang, L. | 登録日 | 2011-08-17 | 公開日 | 2011-08-31 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of human SMYD2 reveals the basis of p53 tumor suppressor methylation J.Biol.Chem., 2011
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6EY3
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6JKK
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![BU of 6jkk by Molmil](/molmil-images/mine/6jkk) | Crystal structure of BubR1 kinase domain | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Mitotic checkpoint control protein kinase BUB1 | 著者 | Lin, L, Ye, S, Huang, Y, Liu, X, Zhang, R, Yao, X. | 登録日 | 2019-03-01 | 公開日 | 2019-06-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res., 29, 2019
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7O2L
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![BU of 7o2l by Molmil](/molmil-images/mine/7o2l) | Yeast 20S proteasome in complex with the covalently bound inhibitor b-lactone (2R,3S)-3-isopropyl-4-oxo-2-oxetane-carboxylate (IOC) | 分子名称: | (2 {R},3 {S})-3-methanoyl-4-methyl-2-hydroxy-pentanoic acid, 20S proteasome, BJ4_G0020160.mRNA.1.CDS.1, ... | 著者 | Shi, Y.M, Hirschmann, M, Shi, Y.N, Shabbir, A, Abebew, D, Tobias, N.J, Gruen, P, Crames, J.J, Poeschel, L, Kuttenlochner, W, Richter, C, Herrmann, J, Mueller, R, Thanwisai, A, Pidot, S.J, Stinear, T.P, Groll, M, Kim, Y, Bode, H. | 登録日 | 2021-03-30 | 公開日 | 2022-04-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria. Nat.Chem., 14, 2022
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5OTN
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![BU of 5otn by Molmil](/molmil-images/mine/5otn) | Crystal structure of zebrafish MTH1 in complex with O6-methyl-dGMP | 分子名称: | 1,2-ETHANEDIOL, 6-O-METHYL GUANOSINE-5'-MONOPHOSPHATE, CALCIUM ION, ... | 著者 | Gustafsson, R, Henriksson, L, Jemth, A.-S, Brautigam, L, Carreras Puigvert, J, Homan, E, Warpman Berglund, U, Helleday, T, Stenmark, P. | 登録日 | 2017-08-22 | 公開日 | 2018-09-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (0.99 Å) | 主引用文献 | MutT homologue 1 (MTH1) catalyzes the hydrolysis of mutagenic O6-methyl-dGTP. Nucleic Acids Res., 46, 2018
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1XC3
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![BU of 1xc3 by Molmil](/molmil-images/mine/1xc3) | Structure of a Putative Fructokinase from Bacillus subtilis | 分子名称: | GLYCEROL, PLATINUM (II) ION, Putative fructokinase, ... | 著者 | Cuff, M.E, Quartey, P, Lezondra, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2004-08-31 | 公開日 | 2004-10-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural studies of ROK fructokinase YdhR from Bacillus subtilis: insights into substrate binding and fructose specificity. J.Mol.Biol., 406, 2011
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7OLE
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![BU of 7ole by Molmil](/molmil-images/mine/7ole) | Cryo-EM structure of the TELO2-TTI1-TTI2-RUVBL1-RUVBL2 complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2, ... | 著者 | Pal, M, Llorca, O, Pearl, L. | 登録日 | 2021-05-19 | 公開日 | 2021-07-07 | 最終更新日 | 2021-10-06 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone. Cell Rep, 36, 2021
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