3TG5

Structure of SMYD2 in complex with p53 and SAH

Summary for 3TG5

• Entry DOI: 10.2210/pdb3tg5/pdb
• Related: 3TG4
• Descriptor: N-lysine methyltransferase SMYD2, Cellular tumor antigen p53, GLYCEROL, ... (6 entities in total)
• Functional Keywords: set domain, methyltransferase, co factor binding, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, cytosol (By similarity): Q9NRG4; Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637
• Total number of polymer chains: 2
• Total formula weight: 51674.25

Authors

Zhao, K.,Wang, L. (deposition date: 2011-08-17, release date: 2011-08-31, Last modification date: 2023-11-01)

• Primary citation: Wang, L.,Li, L.,Zhang, H.,Luo, X.,Dai, J.,Zhou, S.,Gu, J.,Zhu, J.,Atadja, P.,Lu, C.,Li, E.,Zhao, K.; Structure of human SMYD2 reveals the basis of p53 tumor suppressor methylation; J.Biol.Chem., 2011; PubMed: 21880715; DOI: 10.1074/jbc.M111.262410

Experimental method

X-RAY DIFFRACTION (2.3 Å)