3TG5
Structure of SMYD2 in complex with p53 and SAH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | N-lysine methyltransferase SMYD2 | polymer | 433 | 49760.1 | 1 | UniProt (Q9NRG4) Pfam (PF00856) Pfam (PF01753) | Homo sapiens (human) | HSKM-B, Histone methyltransferase SMYD2, Lysine N-methyltransferase 3C, SET and MYND domain-containing protein 2 |
| 2 | B (B) | Cellular tumor antigen p53 | polymer | 11 | 1241.4 | 1 | UniProt (P04637) | Homo sapiens | Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53 |
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 5 | E, F, G (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 6 | H, I (A, B) | water | water | 18.0 | 209 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51001.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 672.7 | |
| All* | Total formula weight | 51674.3 |
