1XHX
| Phi29 DNA Polymerase, orthorhombic crystal form | 分子名称: | DNA polymerase, MAGNESIUM ION, SULFATE ION | 著者 | Kamtekar, S, Berman, A.J, Wang, J, Lazaro, J.M, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. | 登録日 | 2004-09-21 | 公開日 | 2004-12-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage phi29 Mol.Cell, 16, 2004
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8HF1
| DmDcr-2/R2D2/LoqsPD with 19bp-dsRNA in Trimer state | 分子名称: | Dicer-2, isoform A, LD06392p, ... | 著者 | Su, S, Wang, J, Ma, J. | 登録日 | 2022-11-09 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers. Nat Commun, 14, 2023
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3JTN
| Crystal Structure of the c-terminal domain of YpbH | 分子名称: | Adapter protein mecA 2, IODIDE ION | 著者 | Wang, F, Mei, Z, Qi, Y, Yan, C, Wang, J, Shi, Y. | 登録日 | 2009-09-14 | 公開日 | 2009-09-29 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystal Structure of the MecA degradation tag To be Published
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3JTP
| crystal structure of the C-terminal domain of MecA | 分子名称: | Adapter protein mecA 1, IODIDE ION | 著者 | Wang, F, Mei, Z, Qi, Y, Yan, C, Wang, J, Shi, Y. | 登録日 | 2009-09-14 | 公開日 | 2009-09-29 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | crystal structure of the MecA degradation tag To be Published
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3K3O
| Crystal structure of the catalytic core domain of human PHF8 complexed with alpha-ketoglutarate | 分子名称: | 2-OXOGLUTARIC ACID, FE (II) ION, PHD finger protein 8 | 著者 | Yu, L, Wang, Y, Huang, S, Wang, J, Deng, Z, Wu, W, Gong, W, Chen, Z. | 登録日 | 2009-10-03 | 公開日 | 2010-01-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural insights into a novel histone demethylase PHF8 Cell Res., 20, 2010
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3KHF
| The crystal structure of the PDZ domain of human Microtubule Associated Serine/Threonine Kinase 3 (MAST3) | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Microtubule-associated serine/threonine-protein kinase 3 | 著者 | Roos, A, Elkins, J, Savitsky, P, Wang, J, Ugochukwu, E, Murray, J, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2009-10-30 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | The crystal structure of the PDZ domain of human Microtubule Associated Serine/Threonine Kinase 3 (MAST3) To be Published
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5JPS
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7TOB
| Crystal structure of the SARS-CoV-2 Omicron main protease (Mpro) in complex with inhibitor GC376 | 分子名称: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER | 著者 | Sacco, M.D, Wang, J, Chen, Y. | 登録日 | 2022-01-24 | 公開日 | 2022-02-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The P132H mutation in the main protease of Omicron SARS-CoV-2 decreases thermal stability without compromising catalysis or small-molecule drug inhibition. Cell Res., 32, 2022
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7TQL
| CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B. | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Lapointe, C.P, Grosely, R, Sokabe, M, Alvarado, C, Wang, J, Montabana, E, Villa, N, Shin, B, Dever, T, Fraser, C, Fernandez, I.S, Puglisi, J.D. | 登録日 | 2022-01-26 | 公開日 | 2022-04-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. Nature, 607, 2022
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5KTJ
| Crystal structure of Pistol, a class of self-cleaving ribozyme | 分子名称: | COBALT HEXAMMINE(III), MAGNESIUM ION, Pistol (50-MER), ... | 著者 | Nguyen, L.A, Wang, J, Steitz, T.A. | 登録日 | 2016-07-11 | 公開日 | 2016-10-05 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | 主引用文献 | Crystal structure of Pistol, a class of self-cleaving ribozyme. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6KRX
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2EX3
| Bacteriophage phi29 DNA polymerase bound to terminal protein | 分子名称: | DNA polymerase, DNA terminal protein, LEAD (II) ION | 著者 | Kamtekar, S, Berman, A.J, Wang, J, de Vega, M, Blanco, L, Salas, M, Steitz, T.A. | 登録日 | 2005-11-07 | 公開日 | 2006-03-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The phi29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition Embo J., 25, 2006
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1IH7
| High-Resolution Structure of Apo RB69 DNA Polymerase | 分子名称: | DNA POLYMERASE, GUANOSINE, POTASSIUM ION | 著者 | Franklin, M.C, Wang, J, Steitz, T.A. | 登録日 | 2001-04-18 | 公開日 | 2001-06-13 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structure of the Replicating Complex of a Pol alpha Family DNA Polymerase Cell(Cambridge,Mass.), 105, 2001
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6JJP
| Crystal structure of Fab of a PD-1 monoclonal antibody MW11-h317 in complex with PD-1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of MW11-h317, Programmed cell death protein 1, ... | 著者 | Wang, M, Wang, J, Wang, R, Jiao, S, Wang, S, Zhang, J, Zhang, M. | 登録日 | 2019-02-26 | 公開日 | 2019-10-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Identification of a monoclonal antibody that targets PD-1 in a manner requiring PD-1 Asn58 glycosylation. Commun Biol, 2, 2019
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6WGK
| Fab portion of dupilumab with Crystal Kappa design and intrachain disulfide | 分子名称: | Dupilumab Fab heavy chain, Dupilumab Fab light chain | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | 登録日 | 2020-04-05 | 公開日 | 2020-09-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15, 2020
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6WGL
| Dupilumab fab with Crystal Kappa design complexed with human IL-4 receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dupilumab Fab heavy chain, ... | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | 登録日 | 2020-04-05 | 公開日 | 2020-09-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15, 2020
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6WGB
| Crystal structure of the fab portion of dupilumab | 分子名称: | Dupilumab Fab heavy chain, Dupilumab Fab light chain | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | 登録日 | 2020-04-05 | 公開日 | 2020-09-16 | 最終更新日 | 2020-09-23 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15, 2020
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7KX5
| Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with noncovalent inhibitor Jun8-76-3A | 分子名称: | 3C-like proteinase, GLYCEROL, N-([1,1'-biphenyl]-4-yl)-N-[(1R)-2-oxo-2-{[(1S)-1-phenylethyl]amino}-1-(pyridin-3-yl)ethyl]furan-2-carboxamide | 著者 | Sacco, M, Wang, J, Chen, Y. | 登録日 | 2020-12-03 | 公開日 | 2020-12-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery of Di- and Trihaloacetamides as Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity. J.Am.Chem.Soc., 143, 2021
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5ID6
| Structure of Cpf1/RNA Complex | 分子名称: | Cpf1, MAGNESIUM ION, RNA (5'-R(P*AP*AP*UP*UP*UP*CP*UP*AP*CP*UP*AP*AP*GP*UP*GP*UP*AP*GP*AP*UP*C)-3') | 著者 | Dong, D, Ren, K, Qiu, X, Wang, J, Huang, Z. | 登録日 | 2016-02-24 | 公開日 | 2016-04-27 | 最終更新日 | 2016-05-11 | 実験手法 | X-RAY DIFFRACTION (2.382 Å) | 主引用文献 | The crystal structure of Cpf1 in complex with CRISPR RNA Nature, 532, 2016
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6WG8
| Fab portion of dupilumab with Crystal Kappa design | 分子名称: | Dupilumab Fab heavy chain, Dupilumab Fab light chain, GLYCEROL | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | 登録日 | 2020-04-05 | 公開日 | 2020-09-16 | 最終更新日 | 2020-09-23 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15, 2020
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6WGJ
| Fab portion of dupilumab with Crystal Kappa design and no interchain disulfide | 分子名称: | Dupilumab Fab heavy chain, Dupilumab Fab light chain | 著者 | Druzina, Z, Atwell, S, Pustilnik, A, Antonysamy, S, Ho, C, Lieu, R, Hendle, J, Benach, J, Wang, J. | 登録日 | 2020-04-05 | 公開日 | 2020-09-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Rapid and robust antibody Fab fragment crystallization utilizing edge-to-edge beta-sheet packing. Plos One, 15, 2020
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6T7K
| Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with NCP-26 and L-Proline | 分子名称: | 1,2-ETHANEDIOL, PROLINE, Proline--tRNA ligase, ... | 著者 | Johansson, C, Wang, J, Tye, M, Payne, N.C, Mazitschek, R, Thompson, A, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T. | 登録日 | 2019-10-22 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with NCP-26 and L-Proline To Be Published
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4EBZ
| Crystal structure of the ectodomain of a receptor like kinase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitin elicitor receptor kinase 1, ... | 著者 | Chai, J, Liu, T, Han, Z, She, J, Wang, J. | 登録日 | 2012-03-26 | 公開日 | 2012-06-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.792 Å) | 主引用文献 | Chitin-induced dimerization activates a plant immune receptor. Science, 336, 2012
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4EBY
| Crystal structure of the ectodomain of a receptor like kinase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitin elicitor receptor kinase 1, ... | 著者 | Chai, J, Liu, T, Han, Z, She, J, Wang, J. | 登録日 | 2012-03-25 | 公開日 | 2012-06-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Chitin-induced dimerization activates a plant immune receptor. Science, 336, 2012
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1TAU
| TAQ POLYMERASE (E.C.2.7.7.7)/DNA/B-OCTYLGLUCOSIDE COMPLEX | 分子名称: | 2-O-octyl-beta-D-glucopyranose, DNA (5'-D(*CP*GP*GP*AP*TP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*AP*TP*CP*CP*G)-3'), ... | 著者 | Eom, S.H, Wang, J, Steitz, T.A. | 登録日 | 1996-06-17 | 公開日 | 1997-04-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of Taq ploymerase with DNA at the polymerase active site. Nature, 382, 1996
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