3QXY
 
 | | Human SETD6 in complex with RelA Lys310 | | 分子名称: | 1,2-ETHANEDIOL, N-lysine methyltransferase SETD6, S-ADENOSYLMETHIONINE, ... | | 著者 | Chang, Y, Levy, D, Horton, J.R, Peng, J, Zhang, X, Gozani, O, Cheng, X. | | 登録日 | 2011-03-02 | | 公開日 | 2011-05-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling.
Nucleic Acids Res., 39, 2011
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6IJJ
 | | Photosystem I of Chlamydomonas reinhardtii | | 分子名称: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | | 著者 | Pan, X, Ma, J, Su, X, Liu, Z, Zhang, X, Li, M. | | 登録日 | 2018-10-10 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Antenna arrangement and energy transfer pathways of a green algal photosystem-I-LHCI supercomplex.
Nat Plants, 5, 2019
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3SVM
 | | Human MPP8 - human DNMT3AK47me2 peptide | | 分子名称: | DNA (cytosine-5)-methyltransferase 3A, M-phase phosphoprotein 8 | | 著者 | Chang, Y, Horton, J.R, Zhang, X, Cheng, X. | | 登録日 | 2011-07-12 | | 公開日 | 2011-11-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
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6LT0
 | | cryo-EM structure of C9ORF72-SMCR8-WDR41 | | 分子名称: | Guanine nucleotide exchange C9orf72, Guanine nucleotide exchange protein SMCR8, WD repeat-containing protein 41 | | 著者 | Tang, D, Sheng, J, Xu, L, Zhan, X, Yan, C, Qi, S. | | 登録日 | 2020-01-21 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of C9ORF72-SMCR8-WDR41 reveals the role as a GAP for Rab8a and Rab11a.
Proc.Natl.Acad.Sci.USA, 117, 2020
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8XQX
 | | Cryo-EM structure of the Ycf2-FtsHi motor complex from chlamydomonas reinhardtii in apo state | | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ACP, ... | | 著者 | Liang, K, Zhan, X, Wu, J, Yan, Z. | | 登録日 | 2024-01-05 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Conservation and specialization of the Ycf2-FtsHi chloroplast protein import motor in green algae.
Cell, 2024
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8XQW
 | | Cryo-EM structure of the Ycf2-FtsHi motor complex from Chlamydomonas reinhardtii in AMPPNP bound state | | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ACP, ... | | 著者 | Liang, K, Zhan, X, Wu, J, Yan, Z. | | 登録日 | 2024-01-10 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Conservation and specialization of the Ycf2-FtsHi chloroplast protein import motor in green algae.
Cell, 2024
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6IJO
 | | Photosystem I of Chlamydomonas reinhardtii | | 分子名称: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | | 著者 | Pan, X, Ma, J, Su, X, Liu, Z, Zhang, X, Li, M. | | 登録日 | 2018-10-10 | | 公開日 | 2019-03-20 | | 最終更新日 | 2019-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Antenna arrangement and energy transfer pathways of a green algal photosystem-I-LHCI supercomplex.
Nat Plants, 5, 2019
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8BQN
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8B4J
 | | Rfa1-N-terminal domain in complex with phosphorylated Ddc2 | | 分子名称: | 1,2-ETHANEDIOL, DNA damage checkpoint protein LCD1, Replication factor A protein 1, ... | | 著者 | Yates, L.A, Zhang, X. | | 登録日 | 2022-09-20 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | A DNA damage-induced phosphorylation circuit enhances Mec1 ATR Ddc2 ATRIP recruitment to Replication Protein A.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8B4K
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3SWC
 | | GLP (G9a-like protein) SET domain in complex with Dnmt3aK44me2 peptide | | 分子名称: | DNA (cytosine-5)-methyltransferase 3A, Histone-lysine N-methyltransferase EHMT1, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Chang, Y, Horton, J.R, Zhang, X, Cheng, X. | | 登録日 | 2011-07-13 | | 公開日 | 2011-11-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.332 Å) | | 主引用文献 | MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
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3SW9
 | | GLP (G9a-like protein) SET domain in complex with Dnmt3aK44me0 peptide | | 分子名称: | DNA (cytosine-5)-methyltransferase 3A, Histone-lysine N-methyltransferase EHMT1, SINEFUNGIN, ... | | 著者 | Chang, Y, Horton, J.R, Zhang, X, Cheng, X. | | 登録日 | 2011-07-13 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
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2L97
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3QO2
 | | Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9 | | 分子名称: | 1,2-ETHANEDIOL, Histone H3 peptide, M-phase phosphoprotein 8 | | 著者 | Chang, Y, Horton, J.R, Bedford, M.T, Zhang, X, Cheng, X. | | 登録日 | 2011-02-09 | | 公開日 | 2011-04-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9: potential effect of phosphorylation on methyl-lysine binding.
J.Mol.Biol., 408, 2011
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7ZI4
 | | Cryo-EM structure of the human INO80 complex bound to a WT nucleosome | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Vance, N.R, Ayala, R, Willhoft, O, Tvardovskiy, A, McCormack, E.A, Bartke, T, Zhang, X, Wigley, D.B. | | 登録日 | 2022-04-07 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of the human INO80 complex bound to a WT nucleosome
To Be Published
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8X3S
 | | Crystal structure of human WDR5 in complex with PTEN | | 分子名称: | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, WD repeat-containing protein 5 | | 著者 | Liu, Y, Huang, X, Shang, X. | | 登録日 | 2023-11-14 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | The NTE domain of PTEN alpha / beta promotes cancer progression by interacting with WDR5 via its SSSRRSS motif.
Cell Death Dis, 15, 2024
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5Y9P
 | | Staphylococcus aureus RNase HII | | 分子名称: | GLYCEROL, Ribonuclease HII | | 著者 | Hang, T, Wu, M, Zhang, X. | | 登録日 | 2017-08-26 | | 公開日 | 2018-08-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural insights into a novel functional dimer of Staphylococcus aureus RNase HII
Biochem. Biophys. Res. Commun., 503, 2018
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4TOR
 | | Crystal structure of Tankyrase 1 with IWR-8 | | 分子名称: | 1-[(1-acetyl-5-bromo-1H-indol-6-yl)sulfonyl]-N-ethyl-N-(3-methylphenyl)piperidine-4-carboxamide, CHLORIDE ION, Tankyrase-1, ... | | 著者 | Chen, H, Zhang, X, Lum, L, Chen, C. | | 登録日 | 2014-06-06 | | 公開日 | 2015-05-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | | 主引用文献 | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.
Mol.Cell.Biol., 35, 2015
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4TOS
 | | Crystal structure of Tankyrase 1 with 355 | | 分子名称: | Tankyrase-1, ZINC ION, trans-N-benzyl-4-({1-[(6-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl]-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl}methyl)cyclohexanecarboxamide | | 著者 | Chen, H, Zhang, X, Lum, l, Chen, C. | | 登録日 | 2014-06-06 | | 公開日 | 2015-05-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | | 主引用文献 | Disruption of Wnt/ beta-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.
Mol.Cell.Biol., 35, 2015
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6O0W
 | | Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1 in complex with NADP+ and Bis-Tris | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-2'-5'-DIPHOSPHATE, TIR-NB-LRR type resistance protein RUN1 | | 著者 | Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B. | | 登録日 | 2019-02-17 | | 公開日 | 2019-09-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
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6O0S
 | | Crystal structure of the tandem SAM domains from human SARM1 | | 分子名称: | Sterile alpha and TIR motif-containing protein 1 | | 著者 | Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Deerain, N, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B. | | 登録日 | 2019-02-17 | | 公開日 | 2019-09-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
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6Z3A
 | | Mec1-Ddc2 (wild-type) in complex with AMP-PNP | | 分子名称: | DNA damage checkpoint protein LCD1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase MEC1, ... | | 著者 | Yates, L.A, Zhang, X. | | 登録日 | 2020-05-19 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase.
Nat.Struct.Mol.Biol., 28, 2021
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6O0V
 | | Crystal structure of the TIR domain G601P mutant from human SARM1, crystal form 2 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Sterile alpha and TIR motif-containing protein 1 | | 著者 | Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B. | | 登録日 | 2019-02-17 | | 公開日 | 2019-09-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
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6Z2X
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6Z2W
 | | Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP | | 分子名称: | DNA damage checkpoint protein LCD1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Yates, L.A, Zhang, X. | | 登録日 | 2020-05-18 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | | 主引用文献 | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase.
Nat.Struct.Mol.Biol., 28, 2021
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