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7UXP
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BU of 7uxp by Molmil
Structure of PDL1 in complex with FP28132, a Helicon Polypeptide
分子名称: AMINO GROUP, FP28132, N,N'-(1,4-phenylene)diacetamide, ...
著者Li, K, Agarwal, S, Tokareva, O, Thomson, T, Travaline, T, Tattersfield, H, Wahl, S, Verdine, G, McGee, J.
登録日2022-05-05
公開日2022-12-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries.
Proc.Natl.Acad.Sci.USA, 119, 2022
3SX9
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BU of 3sx9 by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with Bumped Kinase Inhibitor, RM-1-132
分子名称: 3-(6-ethoxynaphthalen-2-yl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
著者Larson, E.T, Merritt, E.A.
登録日2011-07-14
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Multiple determinants for selective inhibition of apicomplexan calcium-dependent protein kinase CDPK1.
J.Med.Chem., 55, 2012
3SOL
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BU of 3sol by Molmil
Crystal structure of the type 2 secretion system pilotin GspS
分子名称: CHLORIDE ION, Type II secretion pathway related protein
著者Korotkov, K.V, Hol, W.G.J.
登録日2011-06-30
公開日2011-07-13
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the pilotin from the enterohemorrhagic Escherichia coli type II secretion system.
J.Struct.Biol., 182, 2013
3STB
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BU of 3stb by Molmil
A complex of two editosome proteins and two nanobodies
分子名称: MP18 RNA editing complex protein, RNA-editing complex protein MP42, single domain antibody VHH
著者Park, Y.-J, Hol, W.
登録日2011-07-09
公開日2011-11-02
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of a heterodimer of editosome interaction proteins in complex with two copies of a cross-reacting nanobody.
Nucleic Acids Res., 40, 2012
3LAD
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BU of 3lad by Molmil
REFINED CRYSTAL STRUCTURE OF LIPOAMIDE DEHYDROGENASE FROM AZOTOBACTER VINELANDII AT 2.2 ANGSTROMS RESOLUTION. A COMPARISON WITH THE STRUCTURE OF GLUTATHIONE REDUCTASE
分子名称: DIHYDROLIPOAMIDE DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE
著者Mattevi, A, Schierbeek, A.J, Hol, W.G.J.
登録日1991-12-11
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Refined crystal structure of lipoamide dehydrogenase from Azotobacter vinelandii at 2.2 A resolution. A comparison with the structure of glutathione reductase.
J.Mol.Biol., 220, 1991
3S84
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BU of 3s84 by Molmil
Dimeric apoA-IV
分子名称: Apolipoprotein A-IV, SULFATE ION
著者Deng, X, Davidson, W.S, Thompson, T.B.
登録日2011-05-27
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Structure of Dimeric Apolipoprotein A-IV and Its Mechanism of Self-Association.
Structure, 20, 2012
1IVB
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BU of 1ivb by Molmil
STRUCTURES OF AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(ACETYLAMINO)-3-HYDROXY-5-NITROBENZOIC ACID, CALCIUM ION, ...
著者Jedrzejas, M.J, Luo, M.
登録日1994-12-12
公開日1995-03-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of aromatic inhibitors of influenza virus neuraminidase.
Biochemistry, 34, 1995
3P0H
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BU of 3p0h by Molmil
Leishmania major Tyrosyl-tRNA synthetase in complex with fisetin, cubic crystal form
分子名称: 3,7,3',4'-TETRAHYDROXYFLAVONE, Tyrosyl-tRNA synthetase
著者Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日2010-09-28
公開日2011-03-23
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Double-Length Tyrosyl-tRNA Synthetase from the Eukaryote Leishmania major Forms an Intrinsically Asymmetric Pseudo-Dimer.
J.Mol.Biol., 409, 2011
3P0I
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BU of 3p0i by Molmil
Leishmania major Tyrosyl-tRNA synthetase in complex with tyrosinol, cubic crystal form
分子名称: 4-[(2S)-2-amino-3-hydroxypropyl]phenol, Tyrosyl-tRNA synthetase
著者Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日2010-09-28
公開日2011-03-23
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献The Double-Length Tyrosyl-tRNA Synthetase from the Eukaryote Leishmania major Forms an Intrinsically Asymmetric Pseudo-Dimer.
J.Mol.Biol., 409, 2011
1INH
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BU of 1inh by Molmil
INFLUENZA A SUBTYPE N2 NEURAMINIDASE COMPLEXED WITH AROMATIC BANA111 INHIBITOR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(ACETYLAMINO)-3-[(AMINOACETYL)AMINO]BENZOIC ACID, CALCIUM ION, ...
著者Jedrzejas, M.J, Luo, M.
登録日1995-07-07
公開日1996-08-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-based inhibitors of influenza virus sialidase. A benzoic acid lead with novel interaction.
J.Med.Chem., 38, 1995
3TGH
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BU of 3tgh by Molmil
GAP50 the anchor in the inner membrane complex of Plasmodium
分子名称: COBALT (II) ION, DIMETHYL SULFOXIDE, Glideosome-associated protein 50, ...
著者Bosch, J, Paige, M.H, Vaidya, A, Bergman, L, Hol, W.G.J.
登録日2011-08-17
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of GAP50, the anchor of the invasion machinery in the inner membrane complex of Plasmodium falciparum.
J.Struct.Biol., 178, 2012
1ING
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BU of 1ing by Molmil
INFLUENZA A SUBTYPE N2 NEURAMINIDASE COMPLEXED WITH AROMATIC BANA109 INHIBITOR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(ACETYLAMINO)-3-[(HYDROXYACETYL)AMINO]BENZOIC ACID, CALCIUM ION, ...
著者Jedrzejas, M.J, Luo, M.
登録日1995-07-07
公開日1996-08-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-based inhibitors of influenza virus sialidase. A benzoic acid lead with novel interaction.
J.Med.Chem., 38, 1995
3P0J
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BU of 3p0j by Molmil
Leishmania major Tyrosyl-tRNA synthetase in complex with tyrosinol, triclinic crystal form 1
分子名称: 4-[(2S)-2-amino-3-hydroxypropyl]phenol, SODIUM ION, Tyrosyl-tRNA synthetase
著者Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日2010-09-28
公開日2011-03-23
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献The Double-Length Tyrosyl-tRNA Synthetase from the Eukaryote Leishmania major Forms an Intrinsically Asymmetric Pseudo-Dimer.
J.Mol.Biol., 409, 2011
3OSS
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BU of 3oss by Molmil
The crystal structure of enterotoxigenic Escherichia coli GspC-GspD complex from the type II secretion system
分子名称: CALCIUM ION, CHLORIDE ION, TYPE 2 SECRETION SYSTEM, ...
著者Korotkov, K.V, Pruneda, J, Hol, W.G.J.
登録日2010-09-09
公開日2011-08-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structural and functional studies on the interaction of GspC and GspD in the type II secretion system.
Plos Pathog., 7, 2011
3TEC
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BU of 3tec by Molmil
CALCIUM BINDING TO THERMITASE. CRYSTALLOGRAPHIC STUDIES OF THERMITASE AT 0, 5 AND 100 MM CALCIUM
分子名称: CALCIUM ION, EGLIN C, THERMITASE
著者Gros, P, Kalk, K.H, Hol, W.G.J.
登録日1990-10-26
公開日1992-01-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Calcium binding to thermitase. Crystallographic studies of thermitase at 0, 5, and 100 mM calcium.
J.Biol.Chem., 266, 1991
1TII
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BU of 1tii by Molmil
ESCHERICHIA COLI HEAT LABILE ENTEROTOXIN TYPE IIB
分子名称: HEAT LABILE ENTEROTOXIN TYPE IIB
著者Van Den Akker, F, Hol, W.G.J.
登録日1996-03-20
公開日1996-08-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of a new heat-labile enterotoxin, LT-IIb.
Structure, 4, 1996
6BFA
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BU of 6bfa by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1553
分子名称: 1-{4-amino-3-[6-(cyclopropyloxy)naphthalen-2-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}-2-methylpropan-2-ol, Calmodulin-domain protein kinase 1
著者Merritt, E.A.
登録日2017-10-26
公開日2017-12-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis.
J. Med. Chem., 59, 2016
6JYS
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BU of 6jys by Molmil
GII.13/21 noroviruses recognize glycans with a terminal beta-galactose via an unconventional glycan binding site
分子名称: THREONINE, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose, beta-D-galactopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)]2-acetamido-2-deoxy-alpha-D-galactopyranose, ...
著者Duan, Z, Xin, C.
登録日2019-04-27
公開日2019-05-22
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.697 Å)
主引用文献GII.13/21 Noroviruses Recognize Glycans with a Terminal beta-Galactose via an Unconventional Glycan Binding Site.
J.Virol., 93, 2019
6JYO
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BU of 6jyo by Molmil
GII.13/21 noroviruses recognize glycans with a terminal beta-galactose via an unconventional glycan binding site
分子名称: norovirus P domain protein
著者Duan, Z, Xin, C.
登録日2019-04-27
公開日2019-05-22
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.502 Å)
主引用文献GII.13/21 Noroviruses Recognize Glycans with a Terminal beta-Galactose via an Unconventional Glycan Binding Site.
J.Virol., 93, 2019
6IN5
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BU of 6in5 by Molmil
Crystal structure of H5N2 hemagglutinin G228S Q226L mutant with 3SLN from A/chicken/Taiwan/0502/2012
分子名称: Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose
著者Lin, T.H, Lee, M.S, Liu, J.S.
登録日2018-10-24
公開日2019-10-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.916 Å)
主引用文献crystal structure of H5 hemagglutinin from A/chicken/Taiwan/0502/2012
To Be Published
6JYN
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BU of 6jyn by Molmil
GII.13/21 noroviruses recognize glycans with a terminal beta-galactose via an unconventional glycan binding site
分子名称: beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, human norovirus P domain protein
著者Duan, Z, Xin, C.
登録日2019-04-26
公開日2019-05-22
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献GII.13/21 Noroviruses Recognize Glycans with a Terminal beta-Galactose via an Unconventional Glycan Binding Site.
J.Virol., 93, 2019
6IJT
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BU of 6ijt by Molmil
Crystal structure of H5N2 hemagglutinin G228S Q226L mutant with 6SLN from A/chicken/Taiwan/0502/2012
分子名称: Hemagglutinin, N-acetyl-alpha-neuraminic acid
著者Lin, T.H, Lee, M.S, Liu, J.S.
登録日2018-10-12
公開日2019-10-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献crystal structure of H5 hemagglutinin from A/chicken/Taiwan/0502/2012
To Be Published
6JYR
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BU of 6jyr by Molmil
GII.13/21 noroviruses recognize glycans with a terminal beta-galactose via an unconventional glycan binding site
分子名称: GLYCEROL, norovirus P domain protein
著者Duan, Z, Xin, C.
登録日2019-04-27
公開日2019-05-22
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献GII.13/21 Noroviruses Recognize Glycans with a Terminal beta-Galactose via an Unconventional Glycan Binding Site.
J.Virol., 93, 2019
3EJ0
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BU of 3ej0 by Molmil
Crystal structure of inorganic pyrophosphatase from burkholderia pseudomallei with bound N-(pyridin-3-ylmethyl) aniline, H32 crystal form
分子名称: Inorganic pyrophosphatase, N-(pyridin-3-ylmethyl)aniline
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2008-09-17
公開日2008-09-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献The role of medical structural genomics in discovering new drugs for infectious diseases.
PLoS Comput Biol, 5, 2009
1FM2
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BU of 1fm2 by Molmil
THE 2 ANGSTROM CRYSTAL STRUCTURE OF CEPHALOSPORIN ACYLASE
分子名称: GLUTARYL 7-AMINOCEPHALOSPORANIC ACID ACYLASE
著者Kim, Y, Yoon, K.H, Khang, Y, Turley, S, Hol, W.G.J.
登録日2000-08-15
公開日2001-08-15
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The 2.0 A crystal structure of cephalosporin acylase.
Structure Fold.Des., 8, 2000

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