6FO0

CryoEM structure of bovine cytochrome bc1 in complex with the anti-malarial compound GSK932121

Summary for 6FO0

Entry DOI	10.2210/pdb6fo0/pdb
EMDB information	4286 8657
Descriptor	Cytochrome b-c1 complex subunit 1, mitochondrial, Cytochrome b-c1 complex subunit 9, PROTOPORPHYRIN IX CONTAINING FE, ... (13 entities in total)
Functional Keywords	cryo-em, inhibitor binding, membrane protein, cytochrome bc1
Biological source	Bos taurus (Bovine) More
Total number of polymer chains	20
Total formula weight	507986.26
Authors	Johnson, R.M.,Amporndanai, K.,O'Neill, P.M.,Fishwick, C.W.G.,Jamson, A.H.,Rawson, S.D.,Hasnain, S.S.,Antonyuk, S.V.,Muench, S.P. (deposition date: 2018-02-05, release date: 2018-02-28, Last modification date: 2019-12-11)
Primary citation	Amporndanai, K.,Johnson, R.M.,O'Neill, P.M.,Fishwick, C.W.G.,Jamson, A.H.,Rawson, S.,Muench, S.P.,Hasnain, S.S.,Antonyuk, S.V. X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery. IUCrJ, 5:200-210, 2018 Cited by PubMed: 29765610 DOI: 10.1107/S2052252518001616 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.1 Å)

Structure validation