1NOP
Crystal structure of human tyrosyl-DNA phosphodiesterase (Tdp1) in complex with vanadate, DNA and a human topoisomerase I-derived peptide
Summary for 1NOP
Entry DOI | 10.2210/pdb1nop/pdb |
Related | 1JY1 1MU7 1MU9 |
Descriptor | 5'-D(*AP*GP*AP*GP*TP*T)-3', tyrosyl-DNA phosphodiesterase 1, topoisomerase I-derived peptide, ... (5 entities in total) |
Functional Keywords | protein-dna complex, vanadate complex, transition state mimic, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 114408.96 |
Authors | Davies, D.R.,Interthal, H.,Champoux, J.J.,Hol, W.G.J. (deposition date: 2003-01-16, release date: 2003-03-11, Last modification date: 2024-02-14) |
Primary citation | Davies, D.R.,Interthal, H.,Champoux, J.J.,Hol, W.G.J. Crystal structure of a transition state mimic for Tdp1 assembled from vanadate, DNA, and a topoisomerase I-derived peptide Chem.Biol., 10:139-147, 2003 Cited by PubMed: 12618186DOI: 10.1016/S1074-5521(03)00021-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report