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8DT8
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BU of 8dt8 by Molmil
LM18/Nb136 bispecific tetra-nanobody immunoglobulin in complex with SARS-CoV-2-6P-Mut7 S protein (focused refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LM18 nanobody, Nb136 nanobody, ...
著者Ozorowski, G, Turner, H.L, Ward, A.B.
登録日2022-07-25
公開日2023-06-14
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.
Proc.Natl.Acad.Sci.USA, 120, 2023
6M0U
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BU of 6m0u by Molmil
Structure of AhSYMRK kinase domain mutant - K625E
分子名称: CACODYLATE ION, CALCIUM ION, Symbiosis receptor kinase SymRK, ...
著者Datta, A.B, Naskar, P.
登録日2020-02-22
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structure of AhSYMRK kinase domain mutant - K625E
To Be Published
8DYT
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BU of 8dyt by Molmil
Cryo-EM structure of 227 Fab in complex with (NPNA)8 peptide
分子名称: 227 Fab heavy chain, 227 Fab light chain, Circumsporozoite protein
著者Martin, G.M, Ward, A.B.
登録日2022-08-05
公開日2023-08-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8E5Q
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BU of 8e5q by Molmil
Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0150303 Complex
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase oxamniquine resistance protein, [2-(dihydroxyamino)-4-({[(3R)-1-[(1H-indol-3-yl)methyl]-3-{[3-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-yl]methyl}amino)phenyl]methanol
著者Taylor, A.B, Alwan, S.N.
登録日2022-08-22
公開日2023-07-26
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis.
Plos Pathog., 19, 2023
8E5R
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BU of 8e5r by Molmil
Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0150610 Complex
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase oxamniquine resistance protein, [4-({[(3R)-1-[(1H-indol-3-yl)methyl]-3-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-yl]methyl}amino)-3-nitrophenyl]methanol
著者Taylor, A.B, Alwan, S.N.
登録日2022-08-22
公開日2023-07-26
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis.
Plos Pathog., 19, 2023
8DYW
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BU of 8dyw by Molmil
Cryo-EM structure of 239 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
分子名称: 239 Fab heavy chain, 239 Fab light chain, Circumsporozoite protein
著者Martin, G.M, Ward, A.B.
登録日2022-08-05
公開日2023-08-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
5EIQ
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BU of 5eiq by Molmil
Human OSCAR ligand-binding domain
分子名称: Osteoclast-associated immunoglobulin-like receptor
著者Hinerman, J.M, Conrady, D.G, Herr, A.B.
登録日2015-10-30
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural basis for collagen recognition by the immune receptor OSCAR.
Blood, 127, 2016
6MHG
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BU of 6mhg by Molmil
Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts
分子名称: Fab311 heavy chain, Fab311 light chain, circumsporozoite protein
著者Cottrell, C.A, Torres, J.L, Ward, A.B.
登録日2018-09-17
公開日2018-10-31
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Cryo-EM structure ofP. falciparumcircumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts.
Sci Adv, 4, 2018
8DZ5
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BU of 8dz5 by Molmil
Cryo-EM structure of 364 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
分子名称: 364 Fab heavy chain, 364 Fab light chain, Circumsporozoite protein
著者Martin, G.M, Ward, A.B.
登録日2022-08-06
公開日2023-08-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8DYX
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BU of 8dyx by Molmil
Cryo-EM structure of 311 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
分子名称: 311 heavy chain, 311 light chain, Circumsporozoite protein
著者Martin, G.M, Ward, A.B.
登録日2022-08-05
公開日2023-08-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8DZ3
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BU of 8dz3 by Molmil
Cryo-EM structure of 337 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
分子名称: 337 Fab heavy chain, 337 Fab light chain, Circumsporozoite protein
著者Martin, G.M, Ward, A.B.
登録日2022-08-06
公開日2023-08-02
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8DZ4
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BU of 8dz4 by Molmil
Cryo-EM structure of 356 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
分子名称: 356 Fab heavy chain, 356 Fab light chain, Circumsporozoite protein
著者Martin, G.M, Ward, A.B.
登録日2022-08-06
公開日2023-08-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8DYY
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BU of 8dyy by Molmil
Cryo-EM structure of 334 Fab in complex with recombinant shortened Plasmodium falciparum circumsporozoite protein (rsCSP)
分子名称: 334 Fab heavy chain, 334 Fab light chain, Circumsporozoite protein
著者Martin, G.M, Ward, A.B.
登録日2022-08-05
公開日2023-08-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun, 14, 2023
8E6K
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BU of 8e6k by Molmil
2H08 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2H08 fragment antigen binding heavy chain, 2H08 fragment antigen binding light chain, ...
著者Turner, H.L, Ozorowski, G, Ward, A.B.
登録日2022-08-22
公開日2023-08-09
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo.
Immunity, 56, 2023
8E6J
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BU of 8e6j by Molmil
3H03 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1)
分子名称: 3H03 fragment antigen binding heavy chain, 3H03 fragment antigen binding light chain, Neuraminidase
著者Turner, H.L, Ozorowski, G, Ward, A.B.
登録日2022-08-22
公開日2023-08-09
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo.
Immunity, 56, 2023
6MGW
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BU of 6mgw by Molmil
Structure of mechanically activated ion channel OSCA1.2 in LMNG
分子名称: Calcium permeable stress-gated cation channel 1
著者Jojoa-Cruz, S, Saotome, K, Patapoutian, A, Ward, A.B.
登録日2018-09-15
公開日2018-11-14
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of the mechanically activated ion channel OSCA1.2.
Elife, 7, 2018
6MZC
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BU of 6mzc by Molmil
Human TFIID BC core
分子名称: Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID subunit 2, ...
著者Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E.
登録日2018-11-05
公開日2018-11-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
8EH5
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BU of 8eh5 by Molmil
Cryo-EM structure of L9 Fab in complex with rsCSP
分子名称: Circumsporozoite protein, L9 Heavy chain, L9 Light chain
著者Martin, G.M, Ward, A.B.
登録日2022-09-13
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9.
Nat Commun, 14, 2023
8DZK
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BU of 8dzk by Molmil
Dbr1 in complex with 5-mer cleavage product
分子名称: FE (II) ION, RNA (5'-R(P*(G46)P*UP*GP*UP*U)-3'), RNA lariat debranching enzyme, ...
著者Clark, N.E, Taylor, A.B.
登録日2022-08-08
公開日2022-08-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the RNA Lariat Debranching Enzyme Dbr1 with Hydrolyzed Phosphorothioate RNA Product.
Biochemistry, 61, 2022
7RSO
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BU of 7rso by Molmil
AMC016 SOSIP.v4.2 in complex with PGV04 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC016 gp120, ...
著者Bader, D.L.V, Cottrell, C.A, Ward, A.B.
登録日2021-08-11
公開日2021-09-15
最終更新日2022-01-26
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献The Glycan Hole Area of HIV-1 Envelope Trimers Contributes Prominently to the Induction of Autologous Neutralization.
J.Virol., 96, 2022
7RSN
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BU of 7rsn by Molmil
AMC018 SOSIP.v4.2 in complex with PGV04 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC018 gp120, ...
著者Cottrell, C.A, Ward, A.B.
登録日2021-08-11
公開日2021-09-15
最終更新日2022-01-26
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献The Glycan Hole Area of HIV-1 Envelope Trimers Contributes Prominently to the Induction of Autologous Neutralization.
J.Virol., 96, 2022
8ESC
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BU of 8esc by Molmil
Structure of the Yeast NuA4 Histone Acetyltransferase Complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ...
著者Patel, A.B, Zukin, S.A, Nogales, E.
登録日2022-10-13
公開日2022-11-16
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure and flexibility of the yeast NuA4 histone acetyltransferase complex.
Elife, 11, 2022
6MZM
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BU of 6mzm by Molmil
Human TFIID bound to promoter DNA and TFIIA
分子名称: SCP DNA (80-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ...
著者Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E.
登録日2018-11-05
公開日2018-11-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZD
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BU of 6mzd by Molmil
Human TFIID Lobe A canonical
分子名称: TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ...
著者Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E.
登録日2018-11-05
公開日2018-11-28
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (9.8 Å)
主引用文献Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6M8N
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BU of 6m8n by Molmil
Endo-fucoidan hydrolase P5AFcnA from glycoside hydrolase family 107
分子名称: CALCIUM ION, MALONATE ION, P5AFcnA
著者Boraston, A.B, Vickers, C.J, Abe, K, Salama-Alber, O.
登録日2018-08-22
公開日2018-10-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Endo-fucoidan hydrolases from glycoside hydrolase family 107 (GH107) display structural and mechanistic similarities to alpha-l-fucosidases from GH29.
J. Biol. Chem., 293, 2018

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件を2024-10-16に公開中

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