8E5R
Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0150610 Complex
Summary for 8E5R
Entry DOI | 10.2210/pdb8e5r/pdb |
Descriptor | Sulfotransferase oxamniquine resistance protein, [4-({[(3R)-1-[(1H-indol-3-yl)methyl]-3-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-yl]methyl}amino)-3-nitrophenyl]methanol, ADENOSINE-3'-5'-DIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | sulfotransferase, parasite, drug resistance, transferase |
Biological source | Schistosoma mansoni |
Total number of polymer chains | 1 |
Total formula weight | 31048.33 |
Authors | |
Primary citation | Alwan, S.N.,Taylor, A.B.,Rhodes, J.,Tidwell, M.,McHardy, S.F.,LoVerde, P.T. Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis. Plos Pathog., 19:e1011018-e1011018, 2023 Cited by PubMed: 37428793DOI: 10.1371/journal.ppat.1011018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
Download full validation report