7O7J
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3B5H
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5LQO
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5Y0U
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4Q9Z
| Human Protein Kinase C Theta in Complex with Compound35 ((1R)-9-(AZETIDIN-3-YLAMINO)-1,8-DIMETHYL-3,5-DIHYDRO[1,2,4]TRIAZINO[3,4-C][1,4]BENZOXAZIN-2(1H)-ONE) | 分子名称: | (1R)-9-(azetidin-3-ylamino)-1,8-dimethyl-3,5-dihydro[1,2,4]triazino[3,4-c][1,4]benzoxazin-2(1H)-one, HUMAN PROTEIN KINASE C THETA, SODIUM ION | 著者 | Argiriadi, M.A, George, D.M. | 登録日 | 2014-05-02 | 公開日 | 2014-07-02 | 最終更新日 | 2015-01-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery of Selective and Orally Bioavailable Protein Kinase C theta (PKC theta ) Inhibitors from a Fragment Hit. J.Med.Chem., 58, 2015
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5YZ3
| Crystal structure of T2R-TTL-28 complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Yu, Y, Chen, Q. | 登録日 | 2017-12-12 | 公開日 | 2018-10-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.545 Å) | 主引用文献 | A Novel Microtubule Inhibitor Overcomes Multidrug Resistance in Tumors. Cancer Res., 78, 2018
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5ZFZ
| Crystal structure of human DUX4 homeodomains bound to A12T DNA mutant | 分子名称: | DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*TP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*AP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4 | 著者 | Li, Y.Y, Wu, B.X, Gan, J.H. | 登録日 | 2018-03-07 | 公開日 | 2018-10-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for multiple gene regulation by human DUX4. Biochem. Biophys. Res. Commun., 505, 2018
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3T7J
| Crystal structure of Rtt107p (residues 820-1070) | 分子名称: | Regulator of Ty1 transposition protein 107 | 著者 | Li, X, Li, F, Wu, J, Shi, Y. | 登録日 | 2011-07-30 | 公開日 | 2012-02-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.042 Å) | 主引用文献 | Structure of C-terminal Tandem BRCT Repeats of Rtt107 Protein Reveals Critical Role in Interaction with Phosphorylated Histone H2A during DNA Damage Repair J.Biol.Chem., 287, 2012
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4I6L
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8UQP
| Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | 登録日 | 2023-10-24 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome Nat.Struct.Mol.Biol., 2024
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8URH
| Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, mRNA with a 27 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | 登録日 | 2023-10-26 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | 主引用文献 | Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome Nat.Struct.Mol.Biol., 2024
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8UQL
| Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH in loaded state, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | 登録日 | 2023-10-24 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome Nat.Struct.Mol.Biol., 2024
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4RT4
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8UQM
| Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH in loaded state, NusA, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | 登録日 | 2023-10-24 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | 主引用文献 | Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome Nat.Struct.Mol.Biol., 2024
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8DSZ
| PPARg bound to partial agonist H3B-487 | 分子名称: | (2R)-2-{5-[(5-{[(1R)-1-(4-tert-butylphenyl)ethyl]carbamoyl}-2,3-dimethyl-1H-indol-1-yl)methyl]-2-chlorophenoxy}propanoic acid, Peroxisome proliferator-activated receptor gamma | 著者 | Larsen, N.A. | 登録日 | 2022-07-24 | 公開日 | 2022-09-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPAR gamma by inverse agonists. J.Biol.Chem., 298, 2022
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5ULA
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8DSY
| PPARg bound to inverse agonist H3B-343 | 分子名称: | Peroxisome proliferator-activated receptor gamma, {5-[(5-{[(4-tert-butylphenyl)methyl]carbamoyl}-2,3-dimethyl-1H-indol-1-yl)methyl]-2-chlorophenoxy}acetic acid | 著者 | Larsen, N.A. | 登録日 | 2022-07-24 | 公開日 | 2022-09-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPAR gamma by inverse agonists. J.Biol.Chem., 298, 2022
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5XOB
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6V6U
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3T7K
| Complex structure of Rtt107p and phosphorylated histone H2A | 分子名称: | Histone H2A.1, Regulator of Ty1 transposition protein 107 | 著者 | Li, X, Li, F, Wu, J, Shi, Y. | 登録日 | 2011-07-30 | 公開日 | 2012-02-15 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.028 Å) | 主引用文献 | Structure of C-terminal Tandem BRCT Repeats of Rtt107 Protein Reveals Critical Role in Interaction with Phosphorylated Histone H2A during DNA Damage Repair J.Biol.Chem., 287, 2012
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4KM8
| Crystal structure of Sufud60 | 分子名称: | Suppressor of fused homolog | 著者 | Zhang, Y, Qi, X, Zhang, Z, Wu, G. | 登録日 | 2013-05-08 | 公開日 | 2013-11-20 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci. Nat Commun, 4, 2013
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7XC2
| Cryo EM structure of oligomeric complex formed by wheat CNL Sr35 and the effector AvrSr35 of the wheat stem rust pathogen | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Avirulence factor, CNL9 | 著者 | Alexander, F, Li, E.T, Aaron, L, Deng, Y.N, Sun, Y, Chai, J.J. | 登録日 | 2022-03-22 | 公開日 | 2022-09-21 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A wheat resistosome defines common principles of immune receptor channels. Nature, 610, 2022
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4DOU
| Crystal Structure of a Single-chain Trimer of Human Adiponectin Globular Domain | 分子名称: | 1,2-ETHANEDIOL, Adiponectin, CALCIUM ION, ... | 著者 | Min, X, Walker, N.P, Wang, Z. | 登録日 | 2012-02-10 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a single-chain trimer of human adiponectin globular domain. Febs Lett., 586, 2012
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5Z5K
| Structure of the DCC-Draxin complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Draxin, ... | 著者 | Liu, Y, Xiao, J, Wang, J. | 登録日 | 2018-01-18 | 公開日 | 2018-06-20 | 最終更新日 | 2021-03-10 | 実験手法 | X-RAY DIFFRACTION (2.493 Å) | 主引用文献 | Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC. Neuron, 97, 2018
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7VKH
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