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6Z4C
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BU of 6z4c by Molmil
The structure of the N-terminal domain of RssB from E. coli
分子名称: Regulator of RpoS
著者Zeth, K, Dimce, M, Terrence, D.M, Schuenemann, V, Dougan, D.
登録日2020-05-25
公開日2020-07-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insight into the RssB-Mediated Recognition and Delivery of sigma s to the AAA+ Protease, ClpXP.
Biomolecules, 10, 2020
6NIY
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BU of 6niy by Molmil
A high-resolution cryo-electron microscopy structure of a calcitonin receptor-heterotrimeric Gs protein complex
分子名称: Calcitonin, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者dal Maso, E, Glukhova, A, Zhu, Y, Garcia-Nafria, J, Tate, C.G, Atanasio, S, Reynolds, C.A, Ramirez-Aportela, E, Carazo, J.-M, Hick, C.A, Furness, S.G.B, Hay, D.L, Liang, Y.-L, Miller, L.J, Christopoulos, A, Wang, M.-W, Wootten, D, Sexton, P.M.
登録日2019-01-02
公開日2019-01-23
最終更新日2020-04-08
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献The Molecular Control of Calcitonin Receptor Signaling.
Acs Pharmacol Transl Sci, 2, 2019
2H3X
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BU of 2h3x by Molmil
Crystal Structure of an Electron Transfer Complex Between Aromatic Amine Dehydrogenase and Azurin from Alcaligenes Faecalis (Form 3)
分子名称: Aromatic Amine Dehydrogenase, Azurin, COPPER (II) ION
著者Sukumar, N, Chen, Z, Leys, D, Scrutton, N.S, Ferrati, D, Merli, A, Rossi, G.L, Bellamy, H.D, Chistoserdov, A, Davidson, V.L, Mathews, F.S.
登録日2006-05-23
公開日2006-11-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of an Electron Transfer Complex between Aromatic Amine Dehydrogenase and Azurin from Alcaligenes faecalis.
Biochemistry, 45, 2006
3HVI
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BU of 3hvi by Molmil
Rat catechol O-methyltransferase in complex with a catechol-type, N6-ethyladenine-containing bisubstrate inhibitor
分子名称: (4S,5S)-1,2-DITHIANE-4,5-DIOL, CHLORIDE ION, Catechol O-methyltransferase, ...
著者Ehler, A, Schlatter, D, Stihle, M, Benz, J, Rudolph, M.G.
登録日2009-06-16
公開日2009-10-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Molecular recognition at the active site of catechol-o-methyltransferase: energetically favorable replacement of a water molecule imported by a bisubstrate inhibitor.
Angew.Chem.Int.Ed.Engl., 48, 2009
6NB9
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BU of 6nb9 by Molmil
Amyloid-Beta (20-34) with L-isoaspartate 23
分子名称: Amyloid-beta A4 protein
著者Sawaya, M.R, Warmack, R.A, Boyer, D.R, Zee, C.T, Richards, L.S, Cascio, D, Gonen, T, Clarke, S.G, Eisenberg, D.S.
登録日2018-12-06
公開日2019-08-07
最終更新日2022-09-07
実験手法ELECTRON CRYSTALLOGRAPHY (1.05 Å)
主引用文献Structure of amyloid-beta (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface.
Nat Commun, 10, 2019
6Z6F
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BU of 6z6f by Molmil
HDAC-PC
分子名称: HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ...
著者Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R.
登録日2020-05-28
公開日2021-02-17
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
6Z6H
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BU of 6z6h by Molmil
HDAC-DC
分子名称: HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ...
著者Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R.
登録日2020-05-28
公開日2021-02-17
実験手法ELECTRON MICROSCOPY (8.55 Å)
主引用文献Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
6Z6O
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BU of 6z6o by Molmil
HDAC-TC
分子名称: HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ...
著者Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R.
登録日2020-05-28
公開日2021-02-17
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
6TAM
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BU of 6tam by Molmil
X-RAY STRUCTURE OF HUMAN K-RAS G12C IN COMPLEX WITH COVALENT ISOQUINOLINONE INHIBITOR (COMPOUND 3)
分子名称: 7-[2,4-bis(fluoranyl)phenyl]-3-[(3~{R})-1-propanoylpyrrolidin-3-yl]-4~{H}-isoquinolin-1-one, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Friberg, A, Nguyen, D.
登録日2019-10-30
公開日2020-04-08
最終更新日2020-06-03
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Computationally Empowered Workflow Identifies Novel Covalent Allosteric Binders for KRASG12C.
Chemmedchem, 15, 2020
6Z6P
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BU of 6z6p by Molmil
HDAC-PC-Nuc
分子名称: DNA (145-MER), HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, ...
著者Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R.
登録日2020-05-28
公開日2021-02-17
実験手法ELECTRON MICROSCOPY (4.43 Å)
主引用文献Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
4ADY
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BU of 4ady by Molmil
Crystal structure of 26S proteasome subunit Rpn2
分子名称: 26S PROTEASOME REGULATORY SUBUNIT RPN2
著者Kulkarni, K, He, J, Da Fonseca, P.C.A, Krutauz, D, Glickman, M.H, Barford, D, Morris, E.P.
登録日2012-01-04
公開日2012-03-14
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Structure of the 26S Proteasome Subunit Rpn2 Reveals its Pc Repeat Domain as a Closed Toroid of Two Concentric Alpha-Helical Rings
Structure, 20, 2012
4AFU
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BU of 4afu by Molmil
Human Chymase - Fynomer Complex
分子名称: CHYMASE, FYNOMER
著者Schlatter, D, Brack, S, Banner, D.W, Batey, S, Benz, J, Bertschinger, J, Huber, W, Joseph, C, Rufer, A, Van Der Kloosters, A, Weber, M, Grabulovski, D, Hennig, M.
登録日2012-01-23
公開日2012-07-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Generation, Characterization and Structural Data of Chymase Binding Proteins Based on the Human Fyn Kinase SH3 Domain.
Mabs, 4, 2012
6TIC
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BU of 6tic by Molmil
Structure of A. niger Fdc I327S variant in complex with benzothiophene 2 carboxylic acid
分子名称: Ferulic acid decarboxylase 1, MANGANESE (II) ION, POTASSIUM ION, ...
著者Leys, D.
登録日2019-11-22
公開日2020-06-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.281 Å)
主引用文献Enzymatic C-H activation of aromatic compounds through CO 2 fixation.
Nat.Chem.Biol., 16, 2020
6TIN
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BU of 6tin by Molmil
Structure of A. niger Fdc WT in complex with FMN and indole 2 carboxylic acid
分子名称: 1H-indole-2-carboxylic acid, FLAVIN MONONUCLEOTIDE, Ferulic acid decarboxylase 1, ...
著者Leys, D.
登録日2019-11-22
公開日2020-06-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Enzymatic C-H activation of aromatic compounds through CO 2 fixation.
Nat.Chem.Biol., 16, 2020
2GTD
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BU of 2gtd by Molmil
Crystal Structure of a Type III Pantothenate Kinase: Insight into the Catalysis of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria
分子名称: Type III Pantothenate Kinase
著者Yang, K, Eyobo, Y, Brand, A.L, Martynowski, D, Tomchick, D.
登録日2006-04-27
公開日2006-08-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of a Type III Pantothenate Kinase: Insight into the Mechanism of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria.
J.Bacteriol., 188, 2006
4AP6
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BU of 4ap6 by Molmil
Crystal structure of human POFUT2 E54A mutant in complex with GDP- fucose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2, ...
著者Chen, C, Keusch, J.J, Klein, D, Hess, D, Hofsteenge, J, Gut, H.
登録日2012-03-30
公開日2012-08-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.401 Å)
主引用文献Structure of Human Pofut2: Insights Into Thrombospondin Type 1 Repeat Fold and O-Fucosylation.
Embo J., 31, 2012
6TGX
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BU of 6tgx by Molmil
Crystal structure of Arabidopsis thaliana NAA60 in complex with a bisubstrate analogue
分子名称: Acyl-CoA N-acyltransferases (NAT) superfamily protein, CARBOXYMETHYL COENZYME *A, MET-VAL-ASN-ALA
著者Layer, D, Kopp, J, Lapouge, K, Sinning, I.
登録日2019-11-18
公開日2020-06-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献The Arabidopsis N alpha -acetyltransferase NAA60 locates to the plasma membrane and is vital for the high salt stress response.
New Phytol., 228, 2020
2H47
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BU of 2h47 by Molmil
Crystal Structure of an Electron Transfer Complex Between Aromatic Amine Dephydrogenase and Azurin from Alcaligenes Faecalis (Form 1)
分子名称: Aromatic Amine Dehydrogenase, Azurin, COPPER (II) ION
著者Sukumar, N, Chen, Z, Leys, D, Scrutton, N.S, Ferrati, D, Merli, A, Rossi, G.L, Bellamy, H.D, Chistoserdov, A, Davidson, V.L, Mathews, F.S.
登録日2006-05-23
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of an Electron Transfer Complex between Aromatic Amine Dehydrogenase and Azurin from Alcaligenes faecalis.
Biochemistry, 45, 2006
6Z5U
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BU of 6z5u by Molmil
Cryo-EM structure of the A. baumannii MlaBDEF complex bound to APPNHP
分子名称: ABC transporter ATP-binding protein, ABC transporter permease, Anti-sigma factor antagonist, ...
著者Mann, D, Bergeron, J.R.C.
登録日2020-05-27
公開日2021-05-05
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure and lipid dynamics in the maintenance of lipid asymmetry inner membrane complex of A. baumannii.
Commun Biol, 4, 2021
3R22
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BU of 3r22 by Molmil
Design, synthesis, and biological evaluation of pyrazolopyridine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (Part I)
分子名称: N-{5-[(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide, Serine/threonine-protein kinase 6
著者Zhang, L, Fan, J, Chong, J.-H, Cesana, A, Tam, B, Gilson, C, Boykin, C, Wang, D, Marcotte, D, Le Brazidec, J.-Y, Aivazian, D, Piao, J, Lundgren, K, Hong, K, Vu, K, Nguyen, K.
登録日2011-03-11
公開日2011-08-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I).
Bioorg.Med.Chem.Lett., 21, 2011
2KPJ
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BU of 2kpj by Molmil
Solution Structure Of Protein SOS-response transcriptional repressor, LexA From Eubacterium rectale. Northeast Structural Genomics Consortium Target ErR9A
分子名称: SOS-response transcriptional repressor, LexA
著者Wu, Y, Eletsky, A, Lee, D, Ghosh, A, Buchwald, W, Zhang, Q, Janjua, H, Garcia, E, Nair, R, Sukumaran, D, Rost, B, Acton, T, Xiao, R, Everett, J, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2009-10-16
公開日2009-11-17
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution Structure Of Protein SOS-response transcriptional repressor, LexA From Eubacterium rectale. Northeast Structural Genomics Consortium Target ErR9A
To be Published
4EE9
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BU of 4ee9 by Molmil
Crystal structure of the RBcel1 endo-1,4-glucanase
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endoglucanase
著者Delsaute, M, Berlemont, R, Van Elder, D, Galleni, M, Bauvois, C.
登録日2012-03-28
公開日2013-04-03
最終更新日2013-08-14
実験手法X-RAY DIFFRACTION (1.381 Å)
主引用文献Three-dimensional structure of RBcel1, a metagenome-derived psychrotolerant family GH5 endoglucanase.
Acta Crystallogr.,Sect.F, 69, 2013
4RV2
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BU of 4rv2 by Molmil
Crystal Structure of (3R)-hydroxyacyl-ACP dehydratase HadAB hetero-dimer from Mycobacterium smegmatis
分子名称: MaoC family protein, SULFATE ION, UPF0336 protein MSMEG_1340/MSMEI_1302
著者Biswas, R, Hazra, D, Dutta, D, Das, A.K.
登録日2014-11-24
公開日2015-02-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of dehydratase component HadAB complex of mycobacterial FAS-II pathway.
Biochem.Biophys.Res.Commun., 458, 2015
5E0Q
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BU of 5e0q by Molmil
Crystal structure of the Nup98 C-terminal domain bound to nanobody TP377
分子名称: Anti-Nup98 Nanobody TP377, Nuclear pore complex protein Nup98-Nup96
著者Pleiner, T, Trakhanov, S, Goerlich, D.
登録日2015-09-29
公開日2015-12-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Nanobodies: site-specific labeling for super-resolution imaging, rapid epitope-mapping and native protein complex isolation.
Elife, 4, 2015
3HVJ
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BU of 3hvj by Molmil
Rat catechol O-methyltransferase in complex with a catechol-type, N6-propyladenine-containing bisubstrate inhibitor
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Catechol O-methyltransferase, ...
著者Ehler, A, Schlatter, D, Stihle, M, Benz, J, Rudolph, M.G.
登録日2009-06-16
公開日2009-10-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Molecular recognition at the active site of catechol-o-methyltransferase: energetically favorable replacement of a water molecule imported by a bisubstrate inhibitor.
Angew.Chem.Int.Ed.Engl., 48, 2009

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