6NB9

Amyloid-Beta (20-34) with L-isoaspartate 23

Summary for 6NB9

Entry DOI	10.2210/pdb6nb9/pdb
EMDB information	0405
Descriptor	Amyloid-beta A4 protein (2 entities in total)
Functional Keywords	protofilament, 2 sub 1 screw symmetry, post-translational modification, isoaspartate, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	1491.67
Authors	Sawaya, M.R.,Warmack, R.A.,Boyer, D.R.,Zee, C.T.,Richards, L.S.,Cascio, D.,Gonen, T.,Clarke, S.G.,Eisenberg, D.S. (deposition date: 2018-12-06, release date: 2019-08-07, Last modification date: 2022-09-07)
Primary citation	Warmack, R.A.,Boyer, D.R.,Zee, C.T.,Richards, L.S.,Sawaya, M.R.,Cascio, D.,Gonen, T.,Eisenberg, D.S.,Clarke, S.G. Structure of amyloid-beta (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface. Nat Commun, 10:3357-3357, 2019 Cited by PubMed: 31350392 DOI: 10.1038/s41467-019-11183-z PDB entries with the same primary citation
Experimental method	ELECTRON CRYSTALLOGRAPHY (1.05 Å)

Structure validation