3I65
| Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based inhibitor DSM1 | 分子名称: | 5-methyl-7-(naphthalen-2-ylamino)-1H-[1,2,4]triazolo[1,5-a]pyrimidine-3,8-diium, Dihydroorotate dehydrogenase homolog, mitochondrial, ... | 著者 | Deng, X, Phillips, M.A. | 登録日 | 2009-07-06 | 公開日 | 2009-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds. J.Biol.Chem., 284, 2009
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3I6R
| Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based inhibitor DSM74 | 分子名称: | 5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine, Dihydroorotate dehydrogenase homolog, mitochondrial, ... | 著者 | Deng, X, Phillips, M.A. | 登録日 | 2009-07-07 | 公開日 | 2009-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds. J.Biol.Chem., 284, 2009
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7P18
| Crystal structure of 3-ketosteroid delta1-dehydrogenase from Sterolibacterium denitrificans in complex with 1,4-androstadiene-3,17-dione | 分子名称: | 3-oxosteroid 1-dehydrogenase, ANDROSTA-1,4-DIENE-3,17-DIONE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Wojcik, P, Mrugala, B, Kurpiewska, K, Szaleniec, M. | 登録日 | 2021-07-01 | 公開日 | 2021-07-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Structure, Mutagenesis, and QM:MM Modeling of 3-Ketosteroid Delta 1 -Dehydrogenase from Sterolibacterium denitrificans ─The Role of a New Putative Membrane-Associated Domain and Proton-Relay System in Catalysis. Biochemistry, 62, 2023
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3I68
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5KP2
| Beta-ketoacyl-ACP synthase III -2 (FabH2) (C113A) from Vibrio Cholerae cocrystallized with octanoyl-CoA: hydrolzed ligand | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2, COENZYME A, OCTANOIC ACID (CAPRYLIC ACID) | 著者 | Hou, J, Zheng, H, Grabowski, M, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-07-01 | 公開日 | 2016-07-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Beta-ketoacyl-ACP synthase III -2 (FabH2) (C113A) from Vibrio Cholerae soaked with octanoyl-CoA: hydrolzed ligand To Be Published
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7A8U
| Crystal structure of sarcomeric protein FATZ-1 (d91-FATZ-1 construct) in complex with rod domain of alpha-actinin-2 | 分子名称: | Alpha-actinin-2, Myozenin-1 | 著者 | Sponga, A, Arolas, J.L, Rodriguez Chamorro, A, Mlynek, G, Hollerl, E, Schreiner, C, Pedron, M, Kostan, J, Ribeiro, E.A, Djinovic-Carugo, K. | 登録日 | 2020-08-31 | 公開日 | 2021-06-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.802 Å) | 主引用文献 | Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with alpha-actinin. Sci Adv, 7, 2021
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7A8T
| Crystal structure of sarcomeric protein FATZ-1 (mini-FATZ-1 construct) in complex with rod domain of alpha-actinin-2 | 分子名称: | Alpha-actinin-2, Myozenin-1 | 著者 | Sponga, A, Arolas, J.L, Rodriguez Chamorro, A, Mlynek, G, Hollerl, E, Schreiner, C, Pedron, M, Kostan, J, Ribeiro, E.A, Djinovic-Carugo, K. | 登録日 | 2020-08-31 | 公開日 | 2021-06-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with alpha-actinin. Sci Adv, 7, 2021
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2M1E
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7ANK
| Crystal structure of sarcomeric protein FATZ-1 (d91-FATZ-1 construct) in complex with half dimer of alpha-actinin-2 | 分子名称: | Alpha-actinin-2, Myozenin-1 | 著者 | Sponga, A, Arolas, J.L, Rodriguez Chamorro, A, Mlynek, G, Hollerl, E, Schreiner, C, Pedron, M, Kostan, J, Ribeiro, E.A, Djinovic-Carugo, K. | 登録日 | 2020-10-12 | 公開日 | 2021-06-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.204 Å) | 主引用文献 | Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with alpha-actinin. Sci Adv, 7, 2021
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4IOJ
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4IOM
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4IOK
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4IOL
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2M1D
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2ONE
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3Q3V
| Crystal structure of Phosphoglycerate Kinase from Campylobacter jejuni. | 分子名称: | FORMIC ACID, POTASSIUM ION, Phosphoglycerate kinase, ... | 著者 | Filippova, E.V, Wawrzak, Z, Onopriyenko, O, Edwards, A, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-12-22 | 公開日 | 2011-01-12 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.145 Å) | 主引用文献 | Crystal structures of putative phosphoglycerate kinases from B. anthracis and C. jejuni. J.Struct.Funct.Genom., 13, 2012
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3QUS
| Crystal Structure of N10-Formyltetrahydrofolate Synthetase with ATPgS | 分子名称: | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, Formate--tetrahydrofolate ligase, MALEIC ACID, ... | 著者 | Celeste, L.R, Chai, G, Bielak, M, Lovelace, L.L, Lebioda, L. | 登録日 | 2011-02-24 | 公開日 | 2011-12-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Crystal Strucutre of N10-Formyltetrahydrofolate Synthetase with ATPgS To be Published
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2SNV
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2SNW
| SINDBIS VIRUS CAPSID PROTEIN, TYPE3 CRYSTAL FORM | 分子名称: | COAT PROTEIN C | 著者 | Choi, H.-K, Lee, S, Zhang, Y.-P, Mckinney, B.R, Wengler, G, Rossmann, M.G, Kuhn, R.J. | 登録日 | 1998-02-17 | 公開日 | 1998-04-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. J.Mol.Biol., 262, 1996
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5TBO
| Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM421 | 分子名称: | 2-(1,1-difluoroethyl)-5-methyl-N-[6-(trifluoromethyl)pyridin-3-yl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | 著者 | Deng, X, Phillips, M. | 登録日 | 2016-09-12 | 公開日 | 2016-09-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.151 Å) | 主引用文献 | A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria. ACS Infect Dis, 2, 2016
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6VBX
| Crystal structure of Mcl-1 in complex with 138E12 peptide, Lys-covalent antagonist | 分子名称: | Induced myeloid leukemia cell differentiation protein Mcl-1, Synthetic peptide | 著者 | Pellecchia, M, Perry, J.J, Kenjic, N, Assar, Z. | 登録日 | 2019-12-19 | 公開日 | 2020-12-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Design, Synthesis, and Structural Characterization of Lysine Covalent BH3 Peptides Targeting Mcl-1. J.Med.Chem., 64, 2021
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4JIM
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4JJK
| Crystal Structure of N10-Formyltetrahydrofolate Synthetase with Folate | 分子名称: | 1,2-ETHANEDIOL, 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, FOLIC ACID, ... | 著者 | Celeste, L.R, Lovelace, L.L, Lebioda, L. | 登録日 | 2013-03-08 | 公開日 | 2013-03-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Mechanism of N10-formyltetrahydrofolate synthetase derived from complexes with intermediates and inhibitors. Protein Sci., 21, 2012
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4JJZ
| Crystal Structure of N10-Formyltetrahydrofolate Synthetase with ADP and Formylphosphate | 分子名称: | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, ADENOSINE-5'-DIPHOSPHATE, Formate--tetrahydrofolate ligase, ... | 著者 | Celeste, L.R, Lovelace, L.L, Lebioda, L. | 登録日 | 2013-03-08 | 公開日 | 2013-03-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mechanism of N10-formyltetrahydrofolate synthetase derived from complexes with intermediates and inhibitors. Protein Sci., 21, 2012
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4JKI
| Crystal Structure of N10-Formyltetrahydrofolate Synthetase with ZD9331, Formylphosphate, and ADP | 分子名称: | 2,7-dimethyl-6-[(prop-1-yn-1-ylamino)methyl]quinazolin-4(3H)-one, ADENOSINE-5'-DIPHOSPHATE, Formate--tetrahydrofolate ligase, ... | 著者 | Celeste, L.R, Lovelace, L.L, Lebioda, L. | 登録日 | 2013-03-09 | 公開日 | 2013-03-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Mechanism of N10-formyltetrahydrofolate synthetase derived from complexes with intermediates and inhibitors. Protein Sci., 21, 2012
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