3JBT
| Atomic structure of the Apaf-1 apoptosome | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Cytochrome c, ... | 著者 | Zhou, M, Li, Y, Hu, Q, Bai, X, Huang, W, Yan, C, Scheres, S.H.W, Shi, Y. | 登録日 | 2015-10-15 | 公開日 | 2015-11-18 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1 Genes Dev., 29, 2015
|
|
3JD6
| Double octamer structure of retinoschisin, a cell-cell adhesion protein of the retina | 分子名称: | Retinoschisin | 著者 | Tolun, G, Vijayasarathy, C, Huang, R, Zeng, Y, Li, Y, Steven, A.C, Sieving, P.A, Heymann, J.B. | 登録日 | 2016-04-12 | 公開日 | 2016-05-11 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Paired octamer rings of retinoschisin suggest a junctional model for cell-cell adhesion in the retina. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
1DBG
| CRYSTAL STRUCTURE OF CHONDROITINASE B | 分子名称: | 4-deoxy-alpha-D-glucopyranose-(1-3)-[beta-D-glucopyranose-(1-4)]2-O-methyl-beta-L-fucopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-glucopyranuronic acid-(1-2)-[alpha-L-rhamnopyranose-(1-4)]alpha-D-mannopyranose, CHONDROITINASE B | 著者 | Huang, W, Matte, A, Li, Y, Kim, Y.S, Linhardt, R.J, Su, H, Cygler, M. | 登録日 | 1999-11-02 | 公開日 | 2000-01-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of chondroitinase B from Flavobacterium heparinum and its complex with a disaccharide product at 1.7 A resolution. J.Mol.Biol., 294, 1999
|
|
1DPH
| CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11 | 分子名称: | 1,2-DICHLOROETHANE, INSULIN A CHAIN (PH 11), INSULIN B CHAIN (PH 11), ... | 著者 | Gursky, O, Badger, J, Li, Y, Caspar, D.L.D. | 登録日 | 1992-10-30 | 公開日 | 1993-01-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Conformational changes in cubic insulin crystals in the pH range 7-11. Biophys.J., 63, 1992
|
|
3JBL
| Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization | 分子名称: | NLR family CARD domain-containing protein 4 | 著者 | Zhang, L, Chen, S, Ruan, J, Wu, J, Tong, A.B, Yin, Q, Li, Y, David, L, Lu, A, Wang, W.L, Marks, C, Ouyang, Q, Zhang, X, Mao, Y, Wu, H. | 登録日 | 2015-09-05 | 公開日 | 2015-10-21 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization. Science, 350, 2015
|
|
1DBO
| CRYSTAL STRUCTURE OF CHONDROITINASE B | 分子名称: | 4-deoxy-alpha-D-glucopyranose-(1-3)-[beta-D-glucopyranose-(1-4)]2-O-methyl-beta-L-fucopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-glucopyranuronic acid-(1-2)-[alpha-L-rhamnopyranose-(1-4)]alpha-D-mannopyranose, 4-deoxy-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, CHONDROITINASE B | 著者 | Huang, W, Matte, A, Li, Y, Kim, Y.S, Linhardt, R.J, Su, H, Cygler, M. | 登録日 | 1999-11-03 | 公開日 | 2000-01-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of chondroitinase B from Flavobacterium heparinum and its complex with a disaccharide product at 1.7 A resolution. J.Mol.Biol., 294, 1999
|
|
1CPH
| CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11 | 分子名称: | 1,2-DICHLOROETHANE, INSULIN (PH 10), SODIUM ION | 著者 | Gursky, O, Badger, J, Li, Y, Caspar, D.L.D. | 登録日 | 1992-10-30 | 公開日 | 1993-01-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Conformational changes in cubic insulin crystals in the pH range 7-11. Biophys.J., 63, 1992
|
|
1Q18
| Crystal structure of E.coli glucokinase (Glk) | 分子名称: | Glucokinase | 著者 | Lunin, V.V, Li, Y, Schrag, J.D, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2003-07-18 | 公開日 | 2004-07-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Crystal structures of Escherichia coli ATP-dependent glucokinase and its complex with glucose. J.Bacteriol., 186, 2004
|
|
3PFN
| Crystal Structure of human NAD kinase | 分子名称: | NAD kinase, UNKNOWN ATOM OR ION | 著者 | Wang, H, Tempel, W, Wernimont, A.K, Tong, Y, Guan, X, Shen, Y, Li, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2010-10-28 | 公開日 | 2010-11-10 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structure of human NAD kinase to be published
|
|
1PTM
| Crystal structure of E.coli PdxA | 分子名称: | 4-hydroxythreonine-4-phosphate dehydrogenase, PHOSPHATE ION, ZINC ION | 著者 | Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2003-06-23 | 公開日 | 2003-11-04 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway J.Biol.Chem., 278, 2003
|
|
1P9N
| Crystal structure of Escherichia coli MobB. | 分子名称: | Molybdopterin-guanine dinucleotide biosynthesis protein B, SULFATE ION | 著者 | Rangarajan, S.E, Tocilj, A, Li, Y, Iannuzzi, P, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2003-05-12 | 公開日 | 2003-05-20 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecules of Escherichia coli MobB assemble into densely packed hollow cylinders in a crystal lattice with 75% solvent content. Acta Crystallogr.,Sect.D, 59, 2003
|
|
1PS6
| Crystal structure of E.coli PdxA | 分子名称: | 4-HYDROXY-L-THREONINE-5-MONOPHOSPHATE, 4-hydroxythreonine-4-phosphate dehydrogenase, ZINC ION | 著者 | Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M. | 登録日 | 2003-06-20 | 公開日 | 2003-11-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway J.Biol.Chem., 278, 2003
|
|
1PS7
| Crystal structure of E.coli PdxA | 分子名称: | 4-hydroxythreonine-4-phosphate dehydrogenase, ZINC ION | 著者 | Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M. | 登録日 | 2003-06-20 | 公開日 | 2003-11-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway J.Biol.Chem., 278, 2003
|
|
1RW9
| Crystal structure of the Arthrobacter aurescens chondroitin AC lyase | 分子名称: | PHOSPHATE ION, SODIUM ION, chondroitin AC lyase | 著者 | Lunin, V.V, Li, Y, Linhardt, R.J, Miyazono, H, Kyogashima, M, Kaneko, T, Bell, A.W, Cygler, M. | 登録日 | 2003-12-16 | 公開日 | 2004-04-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | High-resolution crystal structure of Arthrobacter aurescens chondroitin AC lyase: an enzyme-substrate complex defines the catalytic mechanism J.Mol.Biol., 337, 2004
|
|
1RWF
| Crystal structure of Arthrobacter aurescens chondroitin AC lyase in complex with chondroitin tetrasaccharide | 分子名称: | 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-2,6-anhydro-3-deoxy-L-xylo-hexonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, PHOSPHATE ION, SODIUM ION, ... | 著者 | Lunin, V.V, Li, Y, Miyazono, H, Kyogashima, M, Bell, A.W, Cygler, M. | 登録日 | 2003-12-16 | 公開日 | 2004-04-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | High-resolution crystal structure of Arthrobacter aurescens chondroitin AC lyase: an enzyme-substrate complex defines the catalytic mechanism J.Mol.Biol., 337, 2004
|
|
6ATG
| Insights to complement factor H recruitment by the borrelial CspZ protein as revealed by structural analysis | 分子名称: | Complement regulator-acquiring surface protein 2 (CRASP-2), HCG40889, isoform CRA_b, ... | 著者 | Liu, A, Yan, H, Wu, Y, Li, Y, Liu, J. | 登録日 | 2017-08-29 | 公開日 | 2018-09-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Insights to complement factor H recruitment by the borrelial CspZ protein as revealed by structural analysis To Be Published
|
|
6P0Q
| Crystal Structure of Ubiquitin-like Domain of Human WDR12 | 分子名称: | 1,2-ETHANEDIOL, Ribosome biogenesis protein WDR12 | 著者 | Halabelian, L, Dong, A, Zeng, H, Li, Y, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | 登録日 | 2019-05-17 | 公開日 | 2019-05-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Crystal Structure of Ubiquitin-like Domain of Human WDR12 to be published
|
|
6PE4
| Yeast Vo motor in complex with 1 VopQ molecule | 分子名称: | Cation transporter, Uncharacterized protein YPR170W-B, V-type proton ATPase subunit a, ... | 著者 | Peng, W, Li, Y, Tomchick, D.R, Orth, K. | 登録日 | 2019-06-20 | 公開日 | 2020-05-20 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | A distinct inhibitory mechanism of the V-ATPase by Vibrio VopQ revealed by cryo-EM. Nat.Struct.Mol.Biol., 27, 2020
|
|
6PDM
| Crystal structure of Human Protein Arginine Methyltransferase 9 (PRMT9) | 分子名称: | Protein arginine N-methyltransferase 9, UNKNOWN ATOM OR ION | 著者 | Halabelian, L, Tempel, W, Zeng, H, Li, Y, Seitova, A, Hutchinson, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | 登録日 | 2019-06-19 | 公開日 | 2019-07-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal structure of Human Protein Arginine Methyltransferase 9 (PRMT9) To Be Published
|
|
6PE5
| Yeast Vo motor in complex with 2 VopQ molecules | 分子名称: | Cation transporter, Uncharacterized protein YPR170W-B, V-type proton ATPase subunit a, ... | 著者 | Peng, W, Li, Y, Tomchick, D.R, Orth, K. | 登録日 | 2019-06-20 | 公開日 | 2020-05-20 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A distinct inhibitory mechanism of the V-ATPase by Vibrio VopQ revealed by cryo-EM. Nat.Struct.Mol.Biol., 27, 2020
|
|
6OOV
| Crystal structure of HMCES SRAP domain in complex with palindromic 3' overhang DNA | 分子名称: | DNA (5'-D(*CP*AP*AP*CP*GP*TP*TP*GP*TP*TP*TP*TP*T)-3'), Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein, UNKNOWN ATOM OR ION | 著者 | Halabelian, L, Zeng, H, Li, Y, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | 登録日 | 2019-04-23 | 公開日 | 2019-05-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of HMCES SRAP domain in complex with palindromic 3' overhang DNA To Be Published
|
|
6OE7
| Crystal structure of HMCES cross-linked to DNA abasic site | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*GP*AP*CP*GP*TP*(DRZ)P*GP*TP*T)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*G)-3'), ... | 著者 | Halabelian, L, Li, Y, Zeng, H, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | 登録日 | 2019-03-27 | 公開日 | 2019-04-24 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition. Nat.Struct.Mol.Biol., 26, 2019
|
|
6OEA
| Crystal structure of HMCES SRAP domain in complex with longer 3' overhang DNA | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*GP*AP*CP*GP*TP*TP*GP*TP*T)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*G)-3'), ... | 著者 | Halabelian, L, Ravichandran, M, Li, Y, Zeng, H, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | 登録日 | 2019-03-27 | 公開日 | 2019-04-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition. Nat.Struct.Mol.Biol., 26, 2019
|
|
6QPW
| Structural basis of cohesin ring opening | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Sister chromatid cohesion protein 1, ... | 著者 | Panne, D, Muir, K.W, Li, Y, Weis, F. | 登録日 | 2019-02-15 | 公開日 | 2020-02-05 | 最終更新日 | 2020-03-18 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | The structure of the cohesin ATPase elucidates the mechanism of SMC-kleisin ring opening. Nat.Struct.Mol.Biol., 27, 2020
|
|
5WZX
| Structural basis for a pentacyclic oleanane-type triterpenoid as a ligand of FXR | 分子名称: | (4aR,6aR,6aS,6bS,8aS,9R,12aR,14bR)-2,2,6a,6b,9,12a-hexamethyl-10-oxidanylidene-1,3,4,5,6,6a,7,8,8a,9,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid, (R,R)-2,3-BUTANEDIOL, Bile acid receptor, ... | 著者 | Lu, Y, Li, Y. | 登録日 | 2017-01-19 | 公開日 | 2018-01-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Identification of an Oleanane-Type Triterpene Hedragonic Acid as a Novel Farnesoid X Receptor Ligand with Liver Protective Effects and Anti-inflammatory Activity Mol. Pharmacol., 93, 2018
|
|