5H0V
 
 | | Crystal structure of H88A mutated human transthyretin | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, Transthyretin | | 著者 | Yokoyama, T, Hanawa, Y, Obita, T, Mizuguchi, M. | | 登録日 | 2016-10-07 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
|
|
5H0X
 | |
5H0W
 | | Crystal structure of H88F mutated human transthyretin | | 分子名称: | SULFATE ION, Transthyretin | | 著者 | Yokoyama, T, Hanawa, Y, Obita, T, Mizuguchi, M. | | 登録日 | 2016-10-07 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | | 主引用文献 | Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
|
|
5H0Y
 | | Crystal structure of H88Y mutated human transthyretin | | 分子名称: | CHLORIDE ION, SULFATE ION, Transthyretin | | 著者 | Yokoyama, T, Hanawa, Y, Obita, T, Mizuguchi, M. | | 登録日 | 2016-10-07 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Stability and crystal structures of His88 mutant human transthyretins
FEBS Lett., 591, 2017
|
|
4PWF
 | | Crystal structure of V30M mutant human transthyretin complexed with ferulic acid phenethyl ester | | 分子名称: | 2-phenylethyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate, Transthyretin | | 著者 | Yokoyama, T, Kosaka, Y, Mizuguchi, M. | | 登録日 | 2014-03-20 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
|
|
4PWH
 | | Crystal structure of V30M mutant human transthyretin complexed with caffeic acid 1,1-dimethylallyl ester | | 分子名称: | 3-methylbut-2-en-1-yl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate, CALCIUM ION, Transthyretin | | 著者 | Yokoyama, T, Kosaka, Y, Mizuguchi, M. | | 登録日 | 2014-03-20 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | | 主引用文献 | Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
|
|
4PWI
 | | Crystal structure of V30M mutant human transthyretin complexed with rosmarinic acid | | 分子名称: | (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, Transthyretin | | 著者 | Yokoyama, T, Kosaka, Y, Mizuguchi, M. | | 登録日 | 2014-03-20 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.494 Å) | | 主引用文献 | Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
|
|
4PWE
 | |
4PWJ
 | | Crystal structure of V30M mutant human transthyretin complexed with nordihydroguaiaretic acid | | 分子名称: | 4-[(2R,3S)-3-[(3,4-DIHYDROXYPHENYL)METHYL]-2-METHYLBUTYL]BENZENE-1,2-DIOL, Transthyretin | | 著者 | Yokoyama, T, Kosaka, Y, Mizuguchi, M. | | 登録日 | 2014-03-20 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
|
|
4PWG
 | | Crystal structure of V30M mutant human transthyretin complexed with caffeic acid ethyl ester | | 分子名称: | CALCIUM ION, Transthyretin, ethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate | | 著者 | Yokoyama, T, Kosaka, Y, Mizuguchi, M. | | 登録日 | 2014-03-20 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | | 主引用文献 | Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
|
|
4PWK
 | | Crystal structure of V30M mutant human transthyretin complexed with dihydroguaiaretic acid | | 分子名称: | 4,4'-[(2R,3R)-2,3-dimethylbutane-1,4-diyl]bis(2-methoxyphenol), Transthyretin | | 著者 | Yokoyama, T, Kosaka, Y, Mizuguchi, M. | | 登録日 | 2014-03-20 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
|
|
4QRF
 | | Crystal structure of V30M mutant human transthyretin complexed with caffeic acid phenethyl ester | | 分子名称: | 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate, Transthyretin | | 著者 | Yokoyama, T, Kosaka, Y, Mizuguchi, M. | | 登録日 | 2014-06-30 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin
J.Med.Chem., 57, 2014
|
|
3J0E
 | | Models for the T. thermophilus ribosome recycling factor and the E. coli elongation factor G bound to the E. coli post-termination complex | | 分子名称: | 30S ribosomal protein S12, Elongation factor G, Ribosome-recycling factor, ... | | 著者 | Yokoyama, T, Shaikh, T.R, Iwakura, N, Kaji, H, Kaji, A, Agrawal, R.K. | | 登録日 | 2011-06-29 | | 公開日 | 2012-04-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (9.9 Å) | | 主引用文献 | Structural insights into initial and intermediate steps of the ribosome-recycling process.
Embo J., 31, 2012
|
|
3J0D
 | | Models for the T. thermophilus ribosome recycling factor bound to the E. coli post-termination complex | | 分子名称: | 30S ribosomal protein S12, 50S ribosomal protein L11, Ribosome-recycling factor, ... | | 著者 | Yokoyama, T, Shaikh, T.R, Iwakura, N, Kaji, H, Kaji, A, Agrawal, R.K. | | 登録日 | 2011-06-29 | | 公開日 | 2012-04-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (11.1 Å) | | 主引用文献 | Structural insights into initial and intermediate steps of the ribosome-recycling process.
Embo J., 31, 2012
|
|
6IP8
 | | Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | | 登録日 | 2018-11-02 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
|
|
6IP6
 | | Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii) | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | | 登録日 | 2018-11-02 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
|
|
6IP5
 | | Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii) | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | | 登録日 | 2018-11-02 | | 公開日 | 2019-05-29 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
|
|
5AYT
 | | Crystal structure of transthyretin in complex with L6 | | 分子名称: | 2-oxidanyl-6-(phenylcarbonyl)benzo[de]isoquinoline-1,3-dione, Transthyretin | | 著者 | Yokoyama, T, Mizuguchi, M, Kai, H. | | 登録日 | 2015-09-03 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural stabilization of transthyretin by a new compound, 6-benzoyl-2-hydroxy-1H-benzo[de]isoquinoline-1,3(2H)-dione
J. Pharmacol. Sci., 129, 2015
|
|
3D6L
 | |
7CCU
 | |
6IMX
 | | Crystal structure of V30M mutated transthyretin in complex with 18-Crown-6 | | 分子名称: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Transthyretin | | 著者 | Yokoyama, T, Kosaka, Y, Matsumoto, K, Kitakami, R, Nabeshima, Y, Mizuguchi, M. | | 登録日 | 2018-10-24 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.602 Å) | | 主引用文献 | Crown Ethers as Transthyretin Amyloidogenesis Inhibitors.
J. Med. Chem., 62, 2019
|
|
6IN4
 | | Crystal structure of apo DAPK1 in the presence of 18-crown-6 | | 分子名称: | Death-associated protein kinase 1, SULFATE ION | | 著者 | Yokoyama, T, Kosaka, Y, Matsumoto, K, Kitakami, R, Nabeshima, Y, Mizuguchi, M. | | 登録日 | 2018-10-24 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crown Ethers as Transthyretin Amyloidogenesis Inhibitor
To Be Published
|
|
6IMY
 | | Crystal structure of V30M mutated transthyretin in complex with 4'-caroboxybenzo-18-Crown-6 | | 分子名称: | 2,3,5,6,8,9,11,12,14,15-decahydro-1,4,7,10,13,16-benzohexaoxacyclooctadecine-18-carboxylic acid, Transthyretin | | 著者 | Yokoyama, T, Kosaka, Y, Matsumoto, K, Kitakami, R, Nabeshima, Y, Mizuguchi, M. | | 登録日 | 2018-10-24 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | | 主引用文献 | Crown Ethers as Transthyretin Amyloidogenesis Inhibitors.
J. Med. Chem., 62, 2019
|
|
6IN2
 | | Crystal structure of BRD1 in complex with 18-Crown-6 | | 分子名称: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, ACETATE ION, Bromodomain-containing protein 1 | | 著者 | Yokoyama, T, Kosaka, Y, Matsumoto, K, Kitakami, R, Nabeshima, Y, Mizuguchi, M. | | 登録日 | 2018-10-24 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crown Ethers as Transthyretin Amyloidogenesis Inhibitor
To Be Published
|
|
6IN1
 | | Crystal structure of the first bromodomain of BRD4 in complex with 18-Crown-6 | | 分子名称: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Bromodomain-containing protein 4, N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide, ... | | 著者 | Yokoyama, T, Kosaka, Y, Matsumoto, K, Kitakami, R, Nabeshima, Y, Mizuguchi, M. | | 登録日 | 2018-10-24 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crown Ethers as Transthyretin Amyloidogenesis Inhibitor
To Be Published
|
|
