8K1M
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![BU of 8k1m by Molmil](/molmil-images/mine/8k1m) | mycobacterial efflux pump, apo state | 分子名称: | (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CARDIOLIPIN, Multidrug efflux system ATP-binding protein Rv1218c, ... | 著者 | Wang, Y, Wu, F, Zhang, L, Rao, Z. | 登録日 | 2023-07-11 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | mycobacterial efflux pump, apo state To Be Published
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8K1P
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![BU of 8k1p by Molmil](/molmil-images/mine/8k1p) | mycobacterial efflux pump, ADP+vanadate bound state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CARDIOLIPIN, ... | 著者 | Wang, Y, Wu, F, Zhang, L, Rao, Z. | 登録日 | 2023-07-11 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | mycobacterial efflux pump, ADP+vanadate bound state To Be Published
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3DET
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![BU of 3det by Molmil](/molmil-images/mine/3det) | Structure of the E148A, Y445A doubly ungated mutant of E.coli CLC_Ec1, Cl-/H+ antiporter | 分子名称: | Fab fragment, Heavy chain, Light chain, ... | 著者 | Jayaram, H, Accardi, A, Wu, F, Williams, C, Miller, C. | 登録日 | 2008-06-10 | 公開日 | 2008-06-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger Proc.Natl.Acad.Sci.USA, 105, 2008
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3ND0
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![BU of 3nd0 by Molmil](/molmil-images/mine/3nd0) | X-ray crystal structure of a slow cyanobacterial Cl-/H+ antiporter | 分子名称: | CHLORIDE ION, Sll0855 protein | 著者 | Jayaram, H, Robertson, J, Wu, F, Williams, C, Miller, C. | 登録日 | 2010-06-06 | 公開日 | 2011-01-19 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of a Slow CLC Cl(-)/H(+) Antiporter from a Cyanobacterium. Biochemistry, 50, 2011
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3NCY
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![BU of 3ncy by Molmil](/molmil-images/mine/3ncy) | X-ray crystal structure of an arginine agmatine antiporter (AdiC) in complex with a Fab fragment | 分子名称: | AdiC, Fab Heavy chain, Fab Light chain | 著者 | Fang, Y, Jayaram, H, Shane, T, Komalkova-Partensky, L, Wu, F, Williams, C, Xiong, Y, Miller, C. | 登録日 | 2010-06-06 | 公開日 | 2010-08-18 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of a prokaryotic virtual proton pump at 3.2 A resolution. Nature, 460, 2009
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5VEW
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![BU of 5vew by Molmil](/molmil-images/mine/5vew) | Structure of the human GLP-1 receptor complex with PF-06372222 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Glucagon-like peptide 1 receptor,Endolysin chimera, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine, ... | 著者 | Song, G, Yang, D, Wang, Y, Graaf, C.D, Zhou, Q, Jiang, S, Liu, K, Cai, X, Dai, A, Lin, G, Liu, D, Wu, F, Wu, Y, Zhao, S, Ye, L, Han, G.W, Lau, J, Wu, B, Hanson, M.A, Liu, Z.-J, Wang, M.-W, Stevens, R.C. | 登録日 | 2017-04-05 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. Nature, 546, 2017
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5VEX
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![BU of 5vex by Molmil](/molmil-images/mine/5vex) | Structure of the human GLP-1 receptor complex with NNC0640 | 分子名称: | 4-{[(4-cyclohexylphenyl){[3-(methylsulfonyl)phenyl]carbamoyl}amino]methyl}-N-(1H-tetrazol-5-yl)benzamide, Glucagon-like peptide 1 receptor, Endolysin chimera | 著者 | Song, G, Yang, D, Wang, Y, Graaf, C.D, Zhou, Q, Jiang, S, Liu, K, Cai, X, Dai, A, Lin, G, Liu, D, Wu, F, Wu, Y, Zhao, S, Ye, L, Han, G.W, Lau, J, Wu, B, Hanson, M.A, Liu, Z.-J, Wang, M.-W, Stevens, R.C. | 登録日 | 2017-04-05 | 公開日 | 2017-05-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. Nature, 546, 2017
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6JXM
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![BU of 6jxm by Molmil](/molmil-images/mine/6jxm) | Crystal Structure of phi29 pRNA domain II | 分子名称: | BARIUM ION, MAGNESIUM ION, RNA (97-mer) | 著者 | Cai, R, Price, I.R, Ding, F, Wu, F, Chen, T, Zhang, Y, Liu, G, Jardine, P.J, Lu, C, Ke, A. | 登録日 | 2019-04-24 | 公開日 | 2019-08-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | 主引用文献 | ATP/ADP modulates gp16-pRNA conformational change in the Phi29 DNA packaging motor. Nucleic Acids Res., 47, 2019
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2MJY
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2M0Q
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![BU of 2m0q by Molmil](/molmil-images/mine/2m0q) | Solution NMR analysis of intact KCNE2 in detergent micelles demonstrate a straight transmembrane helix | 分子名称: | Potassium voltage-gated channel subfamily E member 2 | 著者 | Lai, C, Li, P, Chen, L, Zhang, L, Wu, F, Tian, C. | 登録日 | 2012-11-01 | 公開日 | 2014-04-30 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Differential modulations of KCNQ1 by auxiliary proteins KCNE1 and KCNE2. Sci Rep, 4, 2014
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2MRM
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![BU of 2mrm by Molmil](/molmil-images/mine/2mrm) | |
2LW3
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![BU of 2lw3 by Molmil](/molmil-images/mine/2lw3) | Solution structure of the soluble domain of MmpS4 from Mycobacterium tuberculosis | 分子名称: | Putative membrane protein mmpS4 | 著者 | Xi, Z, Sun, P, Wang, W, Lai, C, Wu, F, Tian, C. | 登録日 | 2012-07-19 | 公開日 | 2013-03-13 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Discovery of a Siderophore Export System Essential for Virulence of Mycobacterium tuberculosis Plos Pathog., 9, 2013
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7W6V
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![BU of 7w6v by Molmil](/molmil-images/mine/7w6v) | Crystal structure of a dicobalt-substituted small laccase at 2.47 angstrom | 分子名称: | COBALT (II) ION, Putative copper oxidase | 著者 | Yang, X, Wu, F, Wu, W, Chen, X, Fan, S, Yu, P, Mao, L. | 登録日 | 2021-12-02 | 公開日 | 2022-11-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | A versatile artificial metalloenzyme scaffold enabling direct bioelectrocatalysis in solution. Sci Adv, 8, 2022
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5ZID
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![BU of 5zid by Molmil](/molmil-images/mine/5zid) | Crystal Structure of human DPP-IV in complex with HL2 | 分子名称: | (2S,3R)-2-amino-9-methoxy-3-(2,4,5-trifluorophenyl)-2,3-dihydro-1H-naphtho[2,1-b]pyran-8-carbonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ... | 著者 | Zhu, L, Li, H, Wu, F. | 登録日 | 2018-03-14 | 公開日 | 2019-03-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal Structure of human DPP-IV in complex with HL2 To Be Published
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7DTY
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![BU of 7dty by Molmil](/molmil-images/mine/7dty) | Structural basis of ligand selectivity conferred by the human glucose-dependent insulinotropic polypeptide receptor | 分子名称: | CHOLESTEROL, Gastric inhibitory polypeptide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhao, F.H, Zhang, C, Zhou, Q.T, Hang, K.N, Zou, X.Y, Chen, Y, Wu, F, Rao, Q.D, Dai, A.T, Yin, W.C, Shen, D.D, Zhang, Y, Xia, T, Stevens, R.C, Xu, H.E, Yang, D.H, Zhao, L.H, Wang, M.W. | 登録日 | 2021-01-06 | 公開日 | 2021-08-04 | 最終更新日 | 2021-08-11 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor. Elife, 10, 2021
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3X1D
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5AZH
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![BU of 5azh by Molmil](/molmil-images/mine/5azh) | Crystal structure of LGG-2 fused with an EEEWEEL peptide | 分子名称: | EEEWEEL peptide,Protein lgg-2, MAGNESIUM ION | 著者 | Watanabe, Y, Fujioka, Y, Noda, N.N. | 登録日 | 2015-10-05 | 公開日 | 2015-12-30 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy. Mol.Cell, 60, 2015
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5AZG
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![BU of 5azg by Molmil](/molmil-images/mine/5azg) | Crystal structure of LGG-1 complexed with a UNC-51 peptide | 分子名称: | CADMIUM ION, Protein lgg-1, Serine/threonine-protein kinase unc-51 | 著者 | Watanabe, Y, Fujioka, Y, Noda, N.N. | 登録日 | 2015-10-05 | 公開日 | 2015-12-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy. Mol.Cell, 60, 2015
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5AZF
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![BU of 5azf by Molmil](/molmil-images/mine/5azf) | Crystal structure of LGG-1 complexed with a WEEL peptide | 分子名称: | CADMIUM ION, Protein lgg-1, SULFATE ION, ... | 著者 | Watanabe, Y, Noda, N.N. | 登録日 | 2015-10-05 | 公開日 | 2015-12-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy. Mol.Cell, 60, 2015
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7XMN
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![BU of 7xmn by Molmil](/molmil-images/mine/7xmn) | Structure of SARS-CoV-2 ORF8 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Maltodextrin-binding protein, ... | 著者 | Chen, X, Xu, W. | 登録日 | 2022-04-26 | 公開日 | 2023-05-31 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Glycosylated, Lipid-Binding, CDR-Like Domains of SARS-CoV-2 ORF8 Indicate Unique Sites of Immune Regulation. Microbiol Spectr, 11, 2023
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3DEJ
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![BU of 3dej by Molmil](/molmil-images/mine/3dej) | Crystal Structures of Caspase-3 with Bound Isoquinoline-1,3,4-trione Derivative Inhibitors | 分子名称: | (1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate, Caspase-3 | 著者 | Wu, J, Du, J, Li, J, Ding, J. | 登録日 | 2008-06-10 | 公開日 | 2008-09-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Isoquinoline-1,3,4-trione Derivatives Inactivate Caspase-3 by Generation of Reactive Oxygen Species J.Biol.Chem., 283, 2008
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3DEH
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![BU of 3deh by Molmil](/molmil-images/mine/3deh) | Crystal Structures of Caspase-3 with Bound Isoquinoline-1,3,4-trione Derivative Inhibitors | 分子名称: | Caspase-3, isoquinoline-1,3,4(2H)-trione | 著者 | Wu, J, Du, J, Li, J, Ding, J. | 登録日 | 2008-06-10 | 公開日 | 2008-09-02 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Isoquinoline-1,3,4-trione Derivatives Inactivate Caspase-3 by Generation of Reactive Oxygen Species J.Biol.Chem., 283, 2008
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4WEJ
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![BU of 4wej by Molmil](/molmil-images/mine/4wej) | Crystal structure of Pseudomonas aeruginosa PBP3 with a R4 substituted allyl monocarbam | 分子名称: | (3R,4S,7Z)-7-(2-amino-1,3-thiazol-4-yl)-4-formyl-1-[({3-[(5R)-5-hydroxy-4-oxo-4,5-dihydropyridin-2-yl]-4-[3-(methylsulfonyl)propyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl}sulfonyl)amino]-10,10-dimethyl-1,6-dioxo-3-(prop-2-en-1-yl)-9-oxa-2,5,8-triazaundec-7-en-11-oic acid, Penicillin-binding protein 3 | 著者 | Ferguson, A.D. | 登録日 | 2014-09-10 | 公開日 | 2015-04-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.045 Å) | 主引用文献 | SAR and Structural Analysis of Siderophore-Conjugated Monocarbam Inhibitors of Pseudomonas aeruginosa PBP3. Acs Med.Chem.Lett., 6, 2015
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4ZS3
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![BU of 4zs3 by Molmil](/molmil-images/mine/4zs3) | Structural complex of 5-aminofluorescein bound to the FTO protein | 分子名称: | 2-OXOGLUTARIC ACID, 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, ... | 著者 | Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X. | 登録日 | 2015-05-13 | 公開日 | 2015-11-04 | 最終更新日 | 2015-11-18 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein J.Am.Chem.Soc., 137, 2015
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4ZS2
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![BU of 4zs2 by Molmil](/molmil-images/mine/4zs2) | Structural complex of FTO/fluorescein | 分子名称: | 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase FTO, ... | 著者 | Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X. | 登録日 | 2015-05-13 | 公開日 | 2015-11-04 | 最終更新日 | 2015-11-18 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein J.Am.Chem.Soc., 137, 2015
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