7DTY

Structural basis of ligand selectivity conferred by the human glucose-dependent insulinotropic polypeptide receptor

Summary for 7DTY

• Entry DOI: 10.2210/pdb7dty/pdb
• EMDB information: 30860
• Descriptor: human glucose-dependent insulinotropic polypeptide receptor, Gastric inhibitory polypeptide, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... (7 entities in total)
• Functional Keywords: glucose-dependent insulinotropic polypeptide receptor; cryo-electron microscopy; g protein-coupled receptor; ligand recognition, structural protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 181419.80

Authors

Zhao, F.H.,Zhang, C.,Zhou, Q.T.,Hang, K.N.,Zou, X.Y.,Chen, Y.,Wu, F.,Rao, Q.D.,Dai, A.T.,Yin, W.C.,Shen, D.D.,Zhang, Y.,Xia, T.,Stevens, R.C.,Xu, H.E.,Yang, D.H.,Zhao, L.H.,Wang, M.W. (deposition date: 2021-01-06, release date: 2021-08-04, Last modification date: 2021-08-11)

• Primary citation: Zhao, F.,Zhang, C.,Zhou, Q.,Hang, K.,Zou, X.,Chen, Y.,Wu, F.,Rao, Q.,Dai, A.,Yin, W.,Shen, D.D.,Zhang, Y.,Xia, T.,Stevens, R.C.,Xu, H.E.,Yang, D.,Zhao, L.,Wang, M.W.; Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor.; Elife, 10:-, 2021; PubMed: 34254582; DOI: 10.7554/eLife.68719

Experimental method

ELECTRON MICROSCOPY (2.98 Å)