6P6B
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6VTI
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![BU of 6vti by Molmil](/molmil-images/mine/6vti) | Solution NMR structure of the N-terminal domain of the Serine/threonine-protein phosphatase 1 regulatory subunit 10, PPP1R10 | 分子名称: | Serine/threonine-protein phosphatase 1 regulatory subunit 10 | 著者 | Lemak, A, Wei, Y, Duan, S, Houliston, S, Penn, L.Z, Arrowsmith, C.H. | 登録日 | 2020-02-12 | 公開日 | 2020-02-26 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase. Nucleic Acids Res., 50, 2022
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6BY9
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![BU of 6by9 by Molmil](/molmil-images/mine/6by9) | Crystal structure of EHMT1 | 分子名称: | Histone-lysine N-methyltransferase EHMT1, UNKNOWN ATOM OR ION | 著者 | Dong, A, Wei, Y, Li, A, Tempel, W, Han, S, Sunnerhagen, M, Penn, L, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | 登録日 | 2017-12-20 | 公開日 | 2018-01-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of EHMT1 to be published
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4XO2
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1S14
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1S16
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4EFB
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![BU of 4efb by Molmil](/molmil-images/mine/4efb) | Crystal structure of DNA ligase | 分子名称: | 4-amino-2-(cyclopentyloxy)-6-{[(1R,2S)-2-hydroxycyclopentyl]oxy}pyrimidine-5-carboxamide, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase, ... | 著者 | Wei, Y, Wang, T, Charifson, P, Xu, W. | 登録日 | 2012-03-29 | 公開日 | 2013-04-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of DNA ligase To be Published
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4EFE
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![BU of 4efe by Molmil](/molmil-images/mine/4efe) | crystal structure of DNA ligase | 分子名称: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase, SULFATE ION, ... | 著者 | Wei, Y, Wang, T, Charifson, P, Xu, W. | 登録日 | 2012-03-29 | 公開日 | 2013-04-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | crystal structure of DNA ligase To be Published
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4F1R
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7LQT
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![BU of 7lqt by Molmil](/molmil-images/mine/7lqt) | Solution NMR structure of the PNUTS amino-terminal Domain fused to Myc Homology Box 0 | 分子名称: | Serine/threonine-protein phosphatase 1 regulatory subunit 10,Myc proto-oncogene protein fusion | 著者 | Lemak, A, Wei, Y, Duan, S, Houliston, S, Penn, L.Z, Arrowsmith, C.H. | 登録日 | 2021-02-15 | 公開日 | 2021-03-03 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase. Nucleic Acids Res., 50, 2022
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3TKA
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![BU of 3tka by Molmil](/molmil-images/mine/3tka) | crystal structure and solution saxs of methyltransferase rsmh from E.coli | 分子名称: | 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, Ribosomal RNA small subunit methyltransferase H, S-ADENOSYLMETHIONINE, ... | 著者 | Gao, Z.Q, Wei, Y, Zhang, H, Dong, Y.H. | 登録日 | 2011-08-25 | 公開日 | 2012-05-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal and solution structures of methyltransferase RsmH provide basis for methylation of C1402 in 16S rRNA. J.Struct.Biol., 179, 2012
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3B92
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3G7B
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3G75
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3G7E
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2OIN
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![BU of 2oin by Molmil](/molmil-images/mine/2oin) | crystal structure of HCV NS3-4A R155K mutant | 分子名称: | NS4A peptide, Polyprotein, ZINC ION | 著者 | Wei, Y. | 登録日 | 2007-01-11 | 公開日 | 2007-06-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Phenotypic and structural analyses of hepatitis C virus NS3 protease Arg155 variants: sensitivity to telaprevir (VX-950) and interferon alpha. J.Biol.Chem., 282, 2007
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7E7Y
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2OI0
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![BU of 2oi0 by Molmil](/molmil-images/mine/2oi0) | Crystal structure analysis 0f the TNF-a Coverting Enzyme (TACE) in complexed with Aryl-sulfonamide | 分子名称: | (3S)-1-{[4-(BUT-2-YN-1-YLOXY)PHENYL]SULFONYL}PYRROLIDINE-3-THIOL, TNF- a Converting Enzyme (TACE), ZINC ION | 著者 | Wei, Y, Rao, G.B, Bandarage, U.K. | 登録日 | 2007-01-10 | 公開日 | 2007-11-27 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Novel thiol-based TACE inhibitors: rational design, synthesis, and SAR of thiol-containing aryl sulfonamides Bioorg.Med.Chem.Lett., 17, 2007
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2P59
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![BU of 2p59 by Molmil](/molmil-images/mine/2p59) | Crystal Structure of Hepatitis C Virus NS3.4A protease | 分子名称: | (2S,3AS,7AS)-1-[(2S)-2-{[(2S)-2-CYCLOHEXYL-2-({[(2R)-4-NITRO-2H-PYRROL-2-YL]CARBONYL}AMINO)ACETYL]AMINO}-3,3-DIMETHYLBUTANOYL]-N-{(1S)-1-[(1R)-2-(CYCLOPROPYLAMINO)-1-HYDROXY-2-OXOETHYL]BUTYL}OCTAHYDRO-1H-INDOLE-2-CARBOXAMIDE, NS3, peptide | 著者 | Perni, R.B, Wei, Y. | 登録日 | 2007-03-14 | 公開日 | 2008-02-05 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Inhibitors of hepatitis C virus NS3.4A protease. Effect of P4 capping groups on inhibitory potency and pharmacokinetics. Bioorg.Med.Chem.Lett., 17, 2007
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5MV1
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![BU of 5mv1 by Molmil](/molmil-images/mine/5mv1) | Crystal structure of the E protein of the Japanese encephalitis virulent virus | 分子名称: | E protein | 著者 | Liu, X, Zhao, X, Na, R, Li, L, Warkentin, E, Witt, J, Lu, X, Wei, Y, Peng, G, Li, Y, Wang, J. | 登録日 | 2017-01-14 | 公開日 | 2018-05-23 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism. Protein Cell, 10, 2019
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5MV2
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![BU of 5mv2 by Molmil](/molmil-images/mine/5mv2) | Crystal structure of the E protein of the Japanese encephalitis live attenuated vaccine virus | 分子名称: | E protein | 著者 | Liu, X, Zhao, X, Na, R, Li, L, Warkentin, E, Witt, J, Lu, X, Wei, Y, Peng, G, Li, Y, Wang, J. | 登録日 | 2017-01-14 | 公開日 | 2018-05-23 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism. Protein Cell, 10, 2019
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1TIB
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6L62
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![BU of 6l62 by Molmil](/molmil-images/mine/6l62) | Neutralization mechanism of a monoclonal antibody targeting a porcine circovirus type 2 Cap protein conformational epitope | 分子名称: | Capsid protein, Heavy chain of Fab fragment, Light chain of Fab fragment | 著者 | Sun, Z, Huang, L, Xia, D, Wei, Y, Sun, E, Zhu, H, Bian, H, Wu, H, Feng, L, Wang, J, Liu, C. | 登録日 | 2019-10-25 | 公開日 | 2020-02-12 | 最終更新日 | 2020-04-29 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Neutralization Mechanism of a Monoclonal Antibody Targeting a Porcine Circovirus Type 2 Cap Protein Conformational Epitope. J.Virol., 94, 2020
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1WAB
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![BU of 1wab by Molmil](/molmil-images/mine/1wab) | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | 分子名称: | ACETATE ION, PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | 著者 | Ho, Y.S, Swenson, L, Derewenda, U, Serre, L, Wei, Y, Dauter, Z, Hattori, M, Aoki, J, Arai, H, Adachi, T, Inoue, K, Derewenda, Z.S. | 登録日 | 1996-10-30 | 公開日 | 1997-11-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer. Nature, 385, 1997
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1TIA
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![BU of 1tia by Molmil](/molmil-images/mine/1tia) | AN UNUSUAL BURIED POLAR CLUSTER IN A FAMILY OF FUNGAL LIPASES | 分子名称: | LIPASE | 著者 | Derewenda, U, Swenson, L, Yamaguchi, S, Wei, Y, Derewenda, Z.S. | 登録日 | 1993-12-06 | 公開日 | 1995-01-26 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | An unusual buried polar cluster in a family of fungal lipases. Nat.Struct.Biol., 1, 1994
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