1S16

Crystal Structure of E. coli Topoisomerase IV ParE 43kDa subunit complexed with ADPNP

Summary for 1S16

• Entry DOI: 10.2210/pdb1s16/pdb
• Related: 1S14
• Descriptor: Topoisomerase IV subunit B, MAGNESIUM ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: two-domain protein complexed with adpnp, isomerase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 88009.45

Authors

Wei, Y.,Gross, C.H. (deposition date: 2004-01-05, release date: 2004-05-04, Last modification date: 2024-02-14)

• Primary citation: Bellon, S.,Parsons, J.D.,Wei, Y.,Hayakawa, K.,Swenson, L.L.,Charifson, P.S.,Lippke, J.A.,Aldape, R.,Gross, C.H.; Crystal structures of Escherichia coli topoisomerase IV ParE subunit (24 and 43 kilodaltons): a single residue dictates differences in novobiocin potency against topoisomerase IV and DNA gyrase.; Antimicrob.Agents Chemother., 48:1856-1864, 2004; PubMed: 15105144; DOI: 10.1128/AAC.48.5.1856-1864.2004

Experimental method

X-RAY DIFFRACTION (2.1 Å)