8PSG
 
 | | Asymmetric unit of the yeast fatty acid synthase in the semi non-rotated state with ACP at the acetyl transferase domain (FASx sample) | | 分子名称: | FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta | | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | | 登録日 | 2023-07-13 | | 公開日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
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8PSF
 | | Asymmetric unit of the yeast fatty acid synthase in non-rotated state with ACP at the acetyl transferase domain (FASx sample) | | 分子名称: | 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ... | | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | | 登録日 | 2023-07-13 | | 公開日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
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8PS1
 | | Asymmetric unit of the yeast fatty acid synthase in the non-rotated state with ACP at the ketosynthase domain (FASamn sample) | | 分子名称: | COENZYME A, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ... | | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | | 登録日 | 2023-07-13 | | 公開日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
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8PSM
 | | Asymmetric unit of the yeast fatty acid synthase in the non-rotated state with ACP at the malonyl/palmitoyl transferase domain (FASx sample) | | 分子名称: | 4'-PHOSPHOPANTETHEINE, FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, ... | | 著者 | Singh, K, Bunzel, G, Graf, B, Yip, K.M, Stark, H, Chari, A. | | 登録日 | 2023-07-13 | | 公開日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Reconstruction of a fatty acid synthesis cycle from acyl carrier protein and cofactor structural snapshots.
Cell, 186, 2023
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5EJ0
 | | The vaccinia virus H3 envelope protein, a major target of neutralizing antibodies, exhibits a glycosyltransferase fold and binds UDP-Glucose | | 分子名称: | 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ... | | 著者 | Singh, K, Gittis, A.G, Gitti, R.K, Ostazesky, S.A, Su, H.P, Garboczi, D.N. | | 登録日 | 2015-10-30 | | 公開日 | 2016-03-16 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Vaccinia Virus H3 Envelope Protein, a Major Target of Neutralizing Antibodies, Exhibits a Glycosyltransferase Fold and Binds UDP-Glucose.
J.Virol., 90, 2016
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3CML
 | | Crystal Structure of the DBL3x domain of the Plasmodium falcipurum VAR2CSA protein | | 分子名称: | Erythrocyte membrane protein 1 | | 著者 | Singh, K, Gittis, A.G, Nguyen, P, Gowda, D.C, Miller, L.H, Garboczi, D.N. | | 登録日 | 2008-03-23 | | 公開日 | 2008-09-02 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A.
Nat.Struct.Mol.Biol., 15, 2008
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3CPZ
 | | Crystal structure of VAR2CSA DBL3x domain in the presence of dodecasaccharide of CSA | | 分子名称: | Erythrocyte membrane protein 1, SULFATE ION | | 著者 | Singh, K, Gittis, A.G, Nguyen, P, Gowda, D.C, Miller, L.H, Garboczi, D.N. | | 登録日 | 2008-04-01 | | 公開日 | 2008-09-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A.
Nat.Struct.Mol.Biol., 15, 2008
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7NHT
 | | Akirin2 bound human proteasome | | 分子名称: | Akirin-2, POTASSIUM ION, Proteasome subunit alpha type-1, ... | | 著者 | Singh, K, Brunner, H, Grishkovskaya, I, de Almeida, M, Hinterndorfer, M, Zuber, J, Haselbach, D. | | 登録日 | 2021-02-11 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
Nature, 599, 2021
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6OHG
 | | Structure of Plasmodium falciparum vaccine candidate Pfs230D1M in complex with the Fab of a transmission blocking antibody | | 分子名称: | 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 4F12 Heavy chain, ... | | 著者 | Garboczi, D.N, Singh, K, Gittis, A.G. | | 登録日 | 2019-04-05 | | 公開日 | 2020-06-17 | | 最終更新日 | 2021-03-31 | | 実験手法 | X-RAY DIFFRACTION (2.385 Å) | | 主引用文献 | Structure and function of a malaria transmission blocking vaccine targeting Pfs230 and Pfs230-Pfs48/45 proteins.
Commun Biol, 3, 2020
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7TXW
 | | Crystal structure of the complex of the malaria sexual stage protein and vaccine target Pfs25 with the Fab fragment of a transmission blocking antibody 1G2 | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ETHANOL, ... | | 著者 | Singh, K, Gittis, A.G, Garboczi, D.N. | | 登録日 | 2022-02-10 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Structural and immunological differences in Plasmodium falciparum sexual stage transmission-blocking vaccines comprised of Pfs25-EPA nanoparticles.
Npj Vaccines, 8, 2023
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8E1A
 | | Structure-based study to overcome cross-reactivity of novel androgen receptor inhibitors | | 分子名称: | 1,2-ETHANEDIOL, 4-[4-(3-fluoro-2-methoxyphenyl)-1,3-thiazol-2-yl]morpholine, Androgen receptor | | 著者 | Lallous, N, Li, H, Radaeva, M, Dalal, K, Leblanc, E, Ban, F, Ciesielski, F, Chow, B, Morin, M, Singh, K, Rennie, P.S, Cherkasov, A. | | 登録日 | 2022-08-10 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structure-Based Study to Overcome Cross-Reactivity of Novel Androgen Receptor Inhibitors.
Cells, 11, 2022
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1KCS
 | | CRYSTAL STRUCTURE OF ANTIBODY PC282 IN COMPLEX WITH PS1 PEPTIDE | | 分子名称: | PC282 IMMUNOGLOBULIN, PS1 peptide | | 著者 | Nair, D.T, Singh, K, Siddiqui, Z, Nayak, B.P, Rao, K.V.S, Salunke, D.M. | | 登録日 | 2001-11-11 | | 公開日 | 2002-05-11 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response.
J.Immunol., 168, 2002
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1KCU
 | | CRYSTAL STRUCTURE OF ANTIBODY PC287 | | 分子名称: | PC287 IMMUNOGLOBULIN | | 著者 | Nair, D.T, Singh, K, Siddiqui, Z, Nayak, B.P, Rao, K.V.S, Salunke, D.M. | | 登録日 | 2001-11-11 | | 公開日 | 2002-05-11 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response.
J.Immunol., 168, 2002
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1KCV
 | | Crystal structure of antibody pc282 | | 分子名称: | PC282 IMMUNOGLOBULIN | | 著者 | Nair, D.T, Singh, K, Siddiqui, Z, Nayak, B.P, Rao, K.V, Salunke, D.M. | | 登録日 | 2001-11-11 | | 公開日 | 2002-05-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response.
J.Immunol., 168, 2002
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1KC5
 | | CRYSTAL STRUCTURE OF ANTIBODY PC287 IN COMPLEX WITH PS1 PEPTIDE | | 分子名称: | PC287 Immunoglobulin, PS1 peptide | | 著者 | Nair, D.T, Singh, K, Siddiqui, Z, Nayak, B.P, Rao, K.V, Salunke, D.M. | | 登録日 | 2001-11-07 | | 公開日 | 2002-07-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response.
J.Immunol., 168, 2002
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1KCR
 | | CRYSTAL STRUCTURE OF ANTIBODY PC283 IN COMPLEX WITH PS1 PEPTIDE | | 分子名称: | PC283 IMMUNOGLOBULIN, PS1 peptide | | 著者 | Nair, D.T, Singh, K, Sahu, N, Rao, K.V.S, Salunke, D.M. | | 登録日 | 2001-11-11 | | 公開日 | 2002-05-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of an antibody bound to an immunodominant peptide epitope: novel features in peptide-antibody recognition.
J.Immunol., 165, 2000
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4LVC
 | | Crystal structure of S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii in complex with adenosine | | 分子名称: | ACETATE ION, ADENOSINE, AMMONIUM ION, ... | | 著者 | Manszewski, T, Singh, K, Imiolczyk, B, Jaskolski, M. | | 登録日 | 2013-07-26 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | An enzyme captured in two conformational states: crystal structure of S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii.
Acta Crystallogr.,Sect.D, 71, 2015
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3LO5
 | | Crystal Structure of the dominant negative S17N mutant of Ras | | 分子名称: | CALCIUM ION, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Nassar, N, Singh, K, Garcia-Diaz, M. | | 登録日 | 2010-02-03 | | 公開日 | 2010-03-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.568 Å) | | 主引用文献 | Structure of the Dominant Negative S17N Mutant of Ras
Biochemistry, 49, 2010
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1Z27
 | | Crystal structure of Native Pvs25, an ookinete protein from Plasmodium vivax. | | 分子名称: | ookinete surface protein Pvs25 | | 著者 | Saxena, A.K, Singh, K, Su, H.P, Klein, M.M, Stowers, A.W, Saul, A.J, Long, C.A, Garboczi, D.N. | | 登録日 | 2005-03-07 | | 公開日 | 2005-12-06 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms
Nat.Struct.Mol.Biol., 13, 2006
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1Z1Y
 | | Crystal structure of Methylated Pvs25, an ookinete protein from Plasmodium vivax | | 分子名称: | YTTERBIUM (III) ION, ookinete surface protein Pvs25 | | 著者 | Saxena, A.K, Singh, K, Su, H.P, Klein, M.M, Stowers, A.W, Saul, A.J, Long, C.A, Garboczi, D.N. | | 登録日 | 2005-03-07 | | 公開日 | 2005-12-06 | | 最終更新日 | 2019-11-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms
Nat.Struct.Mol.Biol., 13, 2006
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1Z3G
 | | Crystal structure of complex between Pvs25 and Fab fragment of malaria transmission blocking antibody 2A8 | | 分子名称: | 2A8 Fab Heavy Chain, 2A8 Fab Light Chain, ookinete surface protein Pvs25 | | 著者 | Saxena, A.K, Singh, K, Su, H.P, Klein, M.M, Stowers, A.W, Saul, A.J, Long, C.A, Garboczi, D.N. | | 登録日 | 2005-03-12 | | 公開日 | 2005-12-06 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms
Nat.Struct.Mol.Biol., 13, 2006
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5J2N
 | | HIV-1 reverse transcriptase in complex with DNA that has incorporated EFdA-MP at the P-(post-translocation) site and dTMP at the N-(pre-translocation) site | | 分子名称: | DNA (27-MER), DNA 5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*G)-3', MAGNESIUM ION, ... | | 著者 | Salie, Z.L, Kirby, K.A, Sarafianos, S.G. | | 登録日 | 2016-03-29 | | 公開日 | 2016-08-03 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.896 Å) | | 主引用文献 | Structural basis of HIV inhibition by translocation-defective RT inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA).
Proc.Natl.Acad.Sci.USA, 113, 2016
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5J2Q
 | | HIV-1 reverse transcriptase in complex with DNA that has incorporated a mismatched EFdA-MP at the N-(pre-translocation) site | | 分子名称: | 2'-deoxy-4'-ethynyl-2-fluoroadenosine 5'-(dihydrogen phosphate), DNA (27-MER), DNA (5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(6FM)P*(6FM))-3'), ... | | 著者 | Salie, Z.L, Kirby, K.A, Sarafianos, S.G. | | 登録日 | 2016-03-29 | | 公開日 | 2016-08-03 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.789 Å) | | 主引用文献 | Structural basis of HIV inhibition by translocation-defective RT inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA).
Proc.Natl.Acad.Sci.USA, 113, 2016
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6VVJ
 | | Cap1G-TPUA | | 分子名称: | RNA (130-MER) | | 著者 | Summers, M.F, Brown, J.D. | | 登録日 | 2020-02-18 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for transcriptional start site control of HIV-1 RNA fate.
Science, 368, 2020
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6VU1
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