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Crystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice Type III
分子名称:	Recombination protein uvsY
著者	Gajewski, S, White, S.W.
登録日	2015-05-19
公開日	2016-03-02
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Structure and mechanism of the phage T4 recombination mediator protein UvsY. Proc.Natl.Acad.Sci.USA, 113, 2016

4ZWT

Crystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice Type IV
分子名称:	Recombination protein uvsY
著者	Gajewski, S, White, S.W.
登録日	2015-05-19
公開日	2016-03-02
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (4.2 Å)
主引用文献	Structure and mechanism of the phage T4 recombination mediator protein UvsY. Proc.Natl.Acad.Sci.USA, 113, 2016

2EKE

Structure of a SUMO-binding-motif mimic bound to Smt3p-Ubc9p: conservation of a noncovalent Ubiquitin-like protein-E2 complex as a platform for selective interactions within a SUMO pathway
分子名称:	SUMO-conjugating enzyme UBC9, Ubiquitin-like protein SMT3
著者	Duda, D.M, Schulman, B.A.
登録日	2007-03-23
公開日	2007-05-29
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structure of a SUMO-binding-motif Mimic Bound to Smt3p-Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein-E2 Complex as a Platform for Selective Interactions within a SUMO Pathway J.Mol.Biol., 369, 2007

6D74

Direct Activation of the Executioner Domain of MLKL by a Select Repertoire of Inositol Phosphates
分子名称:	Mixed lineage kinase domain-like protein
著者	Royappa, G.C, McNamara, D.E, Moldoveanu, T.
登録日	2018-04-24
公開日	2019-05-15
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites. Cell Chem Biol, 26, 2019

8EBM

Structure of KLHDC2 substrate binding domain bound to KLHDC2's C-degron mimic
分子名称:	ASN-GLN-ARG-PHE-GLY-SER-ASN-ASN-THR-SER-GLY-SER, Kelch domain-containing protein 2
著者	Scott, D.C, Schulman, B.A.
登録日	2022-08-31
公開日	2023-02-22
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (1.58 Å)
主引用文献	E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity. Mol.Cell, 83, 2023

8EBN

Structure of KLHDC2-EloB/C tetrameric assembly
分子名称:	Elongin-B, Elongin-C, Kelch domain-containing protein 2
著者	Scott, D.C, Schulman, B.A.
登録日	2022-08-31
公開日	2023-02-22
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity. Mol.Cell, 83, 2023

8EBL

Structure of KLHDC2 substrate binding domain bound to C-degron from EPHB2
分子名称:	GLU-ASP-SER-HIS-LYS-GLU-SER-ASN-ASP-CYS-SER-CYS-GLY-GLY, Kelch domain-containing protein 2
著者	Scott, D.C, Schulman, B.A.
登録日	2022-08-31
公開日	2023-02-22
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (1.37 Å)
主引用文献	E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity. Mol.Cell, 83, 2023

6NXD

TYPE I L-ASPARAGINASE FROM ESCHERICHIA COLI IN COMPLEX WITH CITRATE AT PH 4
分子名称:	1,2-ETHANEDIOL, ASPARAGINE, CHLORIDE ION, ...
著者	Lubkowski, J, Wlodawer, A.
登録日	2019-02-08
公開日	2019-08-07
最終更新日	2020-01-15
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Opportunistic complexes of E. coli L-asparaginases with citrate anions. Sci Rep, 9, 2019

6NXC

ECAI(T162A) MUTANT IN COMPLEX WITH CITRATE AT PH 4
分子名称:	1,2-ETHANEDIOL, ASPARAGINE, CHLORIDE ION, ...
著者	Lubkowski, J, Wlodawer, A.
登録日	2019-02-08
公開日	2019-08-07
最終更新日	2019-11-20
実験手法	X-RAY DIFFRACTION (1.74 Å)
主引用文献	Opportunistic complexes of E. coli L-asparaginases with citrate anions. Sci Rep, 9, 2019

4HNJ

Crystallographic structure of BCL-xL domain-swapped dimer in complex with PUMA BH3 peptide at 2.9A resolution
分子名称:	Bcl-2-binding component 3, Bcl-2-like protein 1
著者	Fisher, J.C, Yun, M.K, White, S.W.
登録日	2012-10-19
公開日	2013-01-23
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis. Nat.Chem.Biol., 9, 2013

4KBL

Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism
分子名称:	E3 ubiquitin-protein ligase ARIH1, ZINC ION
著者	Duda, D.M, Olszewski, J.L, Schulman, B.A.
登録日	2013-04-23
公開日	2013-05-29
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (3.3 Å)
主引用文献	Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism. Structure, 21, 2013

4KC9

Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism
分子名称:	E3 ubiquitin-protein ligase ARIH1, ZINC ION
著者	Duda, D.M, Olszewski, J.L, Schulman, B.A.
登録日	2013-04-24
公開日	2013-05-29
最終更新日	2013-07-03
実験手法	X-RAY DIFFRACTION (3.603 Å)
主引用文献	Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism. Structure, 21, 2013

2LK4

Structural and mechanistic insights into the interaction between PAT Pyk2 and Paxillin LD motif
分子名称:	Protein-tyrosine kinase 2-beta
著者	Vanarotti, M, Miller, D, Guibao, C, Zheng, J.
登録日	2011-10-04
公開日	2012-10-10
最終更新日	2024-05-01
実験手法	SOLUTION NMR
主引用文献	Structural and Mechanistic Insights into the Interaction between Pyk2 and Paxillin LD Motifs. J.Mol.Biol., 426, 2014

2M5B

The NMR structure of the BID-BAK complex
分子名称:	Bcl-2 homologous antagonist/killer, human_BID_BH3_SAHB
著者	Moldoveanu, T, Grace, C.R, Kriwacki, R.W, Green, D.R.
登録日	2013-02-19
公開日	2013-04-17
最終更新日	2023-11-15
実験手法	SOLUTION NMR
主引用文献	BID-induced structural changes in BAK promote apoptosis. Nat.Struct.Mol.Biol., 20, 2013

7N00

Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 648-1025 in complex with AUG-alpha
分子名称:	ALK and LTK ligand 2, ALK tyrosine kinase receptor
著者	Reshetnyak, A.V, Myasnikov, A.G, Rossi, P, Miller, D.J, Kalodimos, C.G.
登録日	2021-05-24
公開日	2021-11-24
最終更新日	2021-12-15
実験手法	ELECTRON MICROSCOPY (2.27 Å)
主引用文献	Mechanism for the activation of the anaplastic lymphoma kinase receptor. Nature, 600, 2021

7MZY

Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 673-986
分子名称:	ACETATE ION, ALK tyrosine kinase receptor
著者	Reshetnyak, A.V, Sowaileh, M, Miller, D.J, Rossi, P, Myasnikov, A.G, Kalodimos, C.G.
登録日	2021-05-24
公開日	2021-11-24
最終更新日	2021-12-15
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Mechanism for the activation of the anaplastic lymphoma kinase receptor. Nature, 600, 2021

7MZZ

AUGbeta - FAM150A - ALKL1 60-128
分子名称:	ALK and LTK ligand 1
著者	Rossi, P, Sowaileh, M, Reshetnyak, A.V, Kalodimos, C.G.
登録日	2021-05-24
公開日	2021-11-24
最終更新日	2023-06-14
実験手法	SOLUTION NMR
主引用文献	Mechanism for the activation of the anaplastic lymphoma kinase receptor. Nature, 600, 2021

7MZW

Anaplastic lymphoma kinase (ALK) extracellular ligand binding region 673-1025
分子名称:	ALK tyrosine kinase receptor
著者	Rossi, P, Sowaileh, M, Reshetnyak, A.V, Kalodimos, C.G.
登録日	2021-05-24
公開日	2021-12-08
最終更新日	2021-12-15
実験手法	SOLUTION NMR
主引用文献	Mechanism for the activation of the anaplastic lymphoma kinase receptor. Nature, 600, 2021

7MZX

AUGalpha - FAM150B - ALKL2 77-152
分子名称:	ALK and LTK ligand 2
著者	Rossi, P, Sowaileh, M, Reshetnyak, A.V, Kalodimos, C.G.
登録日	2021-05-24
公開日	2021-11-24
最終更新日	2023-06-14
実験手法	SOLUTION NMR
主引用文献	Mechanism for the activation of the anaplastic lymphoma kinase receptor. Nature, 600, 2021

2M04

Solution structure of BCL-xL in complex with PUMA BH3 peptide
分子名称:	Bcl-2-binding component 3, Bcl-2-like protein 1
著者	Viacava Follis, A, Royappa, G, Kriwacki, R.W.
登録日	2012-10-19
公開日	2013-01-30
最終更新日	2024-05-01
実験手法	SOLUTION NMR
主引用文献	PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis. Nat.Chem.Biol., 9, 2013

2M03

Solution structure of BCL-xL determined with selective isotope labelling of I,L,V sidechains
分子名称:	Bcl-2-like protein 1
著者	Viacava Follis, A, Royappa, G, Kriwacki, R.W.
登録日	2012-10-19
公開日	2013-01-30
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis. Nat.Chem.Biol., 9, 2013

4XEF

Pyk2-FAT complexed with Leupaxin LD motif LD1
分子名称:	20-mer peptide containing LD1 motif of leupaxin, Protein-tyrosine kinase 2-beta
著者	Miller, D.J.
登録日	2014-12-23
公開日	2015-12-23
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats. Biochemistry, 55, 2016

4XEV

Fusion of Pyk2-FAT domain with Leupaxin LD1 motif, complexed with Leupaxin LD4 peptide
分子名称:	19-mer peptide containing Leupaxin LD4 motif, Fusion protein of Protein-tyrosine kinase 2-beta FAT domain and Leupaxin LD1 motif
著者	Miller, D.J.
登録日	2014-12-24
公開日	2015-12-30
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.0073 Å)
主引用文献	Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats. Biochemistry, 55, 2016

4YWM

Pyrococcus furiosus MCM N-terminal domain beta-turn triple mutant pentameric ring
分子名称:	Cell division control protein 21, SULFATE ION, ZINC ION
著者	Froelich, C.A, Enemark, E.J.
登録日	2015-03-20
公開日	2015-09-23
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (3.2 Å)
主引用文献	MCM ring hexamerization is a prerequisite for DNA-binding. Nucleic Acids Res., 43, 2015

4YWK

Pyrococcus furiosus MCM N-terminal domain with Zinc-binding subdomain B deleted
分子名称:	Cell division control protein 21
著者	Froelich, C.A, Enemark, E.J.
登録日	2015-03-20
公開日	2015-09-23
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (1.55 Å)
主引用文献	MCM ring hexamerization is a prerequisite for DNA-binding. Nucleic Acids Res., 43, 2015

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