5TWP
| Pre-catalytic ternary complex of human Polymerase Mu with incoming nonhydrolyzable UMPNPP | 分子名称: | 1,2-ETHANEDIOL, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), ... | 著者 | Moon, A.F, Pryor, J.M, Ramsden, D.A, Kunkel, T.A, Bebenek, K, Pedersen, L.C. | 登録日 | 2016-11-14 | 公開日 | 2017-07-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu. Nucleic Acids Res., 45, 2017
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5TWS
| Post-catalytic complex of human Polymerase Mu (H329A) with newly incorporated UTP | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Moon, A.F, Pryor, J.M, Ramsden, D.A, Kunkel, T.A, Bebenek, K, Pedersen, L.C. | 登録日 | 2016-11-14 | 公開日 | 2017-07-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu. Nucleic Acids Res., 45, 2017
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5VZC
| Post-catalytic complex of human Polymerase Mu (G433S) mutant with incoming dTTP | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), ... | 著者 | Moon, A.F, Pryor, J.M, Ramsden, D.A, Kunkel, T.A, Bebenek, K, Pedersen, L.C. | 登録日 | 2017-05-27 | 公開日 | 2017-07-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.552 Å) | 主引用文献 | Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu. Nucleic Acids Res., 45, 2017
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5VZ7
| Pre-catalytic ternary complex of human Polymerase Mu (G433A) mutant with incoming nonhydrolyzable UMPNPP | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... | 著者 | Moon, A.F, Pryor, J.M, Ramsden, D.A, Kunkel, T.A, Bebenek, K, Pedersen, L.C. | 登録日 | 2017-05-27 | 公開日 | 2017-07-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.551 Å) | 主引用文献 | Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu. Nucleic Acids Res., 45, 2017
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5VZD
| Pre-catalytic ternary complex of human Polymerase Mu (W434A) mutant with incoming nonhydrolyzable UMPNPP | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... | 著者 | Moon, A.F, Pryor, J.M, Ramsden, D.A, Kunkel, T.A, Bebenek, K, Pedersen, L.C. | 登録日 | 2017-05-27 | 公開日 | 2017-07-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.602 Å) | 主引用文献 | Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu. Nucleic Acids Res., 45, 2017
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2IHM
| Polymerase mu in ternary complex with gapped 11mer DNA duplex and bound incoming nucleotide | 分子名称: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*GP*TP*AP*T)-3', 5'-D(*CP*GP*GP*CP*AP*AP*TP*AP*CP*TP*G)-3', ... | 著者 | Moon, A.F, Pedersen, L.C, Kunkel, T.A. | 登録日 | 2006-09-26 | 公開日 | 2006-12-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural insight into the substrate specificity of DNA Polymerase mu. Nat.Struct.Mol.Biol., 14, 2007
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4QGO
| Crystal structure of NucA from Streptococcus agalactiae with no metal bound | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DNA-entry nuclease (Competence-specific nuclease), ... | 著者 | Pedersen, L.C, Moon, A.F, Gaudu, P. | 登録日 | 2014-05-23 | 公開日 | 2014-11-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural characterization of the virulence factor nuclease A from Streptococcus agalactiae. Acta Crystallogr.,Sect.D, 70, 2014
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3UPQ
| Crystal structure of the pre-catalytic ternary complex of polymerase lambda with an rATP analog opposite a templating T. | 分子名称: | 5'-D(*CP*AP*GP*TP*AP*C)-3', 5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3', 5'-D(P*GP*CP*CP*G)-3', ... | 著者 | Gosavi, R.A, Moon, A.F, Kunkel, T.A, Pedersen, L.C, Bebenek, K. | 登録日 | 2011-11-18 | 公開日 | 2012-05-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The catalytic cycle for ribonucleotide incorporation by human DNA Pol lambda Nucleic Acids Res., 40, 2012
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3UQ2
| Crystal structure of the post-catalytic product complex of polymerase lambda with an rCMP inserted opposite a templating G and dAMP inserted opposite a templating T at the primer terminus. | 分子名称: | 5'-D(*CP*AP*GP*TP*AP)-R(P*CP*A)-3', 5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3', 5'-D(P*GP*CP*CP*G)-3', ... | 著者 | Gosavi, R.A, Moon, A.F, Kunkel, T.A, Pedersen, L.C, Bebenek, K. | 登録日 | 2011-11-18 | 公開日 | 2012-05-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | The catalytic cycle for ribonucleotide incorporation by human DNA Pol lambda Nucleic Acids Res., 40, 2012
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3UQ0
| Crystal structure of the post-catalytic product complex of polymerase lambda with an rAMP at the primer terminus. | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*CP*AP*GP*TP*AP*CP)-R(P*A)-3', 5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3', ... | 著者 | Gosavi, R.A, Moon, A.F, Kunkel, T.A, Pedersen, L.C, Bebenek, K. | 登録日 | 2011-11-18 | 公開日 | 2012-05-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | The catalytic cycle for ribonucleotide incorporation by human DNA Pol lambda Nucleic Acids Res., 40, 2012
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3BD9
| human 3-O-sulfotransferase isoform 5 with bound PAP | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, Heparan sulfate glucosamine 3-O-sulfotransferase 5 | 著者 | Xu, D, Moon, A.F, Song, D, Liu, J, Pedersen, L.C. | 登録日 | 2007-11-14 | 公開日 | 2008-01-29 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Engineering sulfotransferases to modify heparan sulfate. Nat.Chem.Biol., 4, 2008
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4JRB
| Structure of Cockroach Allergen Bla g 1 Tandem Repeat as a EGFP fusion | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, CHLORIDE ION, DODECANE, ... | 著者 | Mueller, G.A, Pedersen, L.C, Lih, F.B, Glesner, J, Moon, A.F, Chapman, M.D, Tomer, K, London, R.E. | 登録日 | 2013-03-21 | 公開日 | 2013-07-24 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.414 Å) | 主引用文献 | The novel structure of the cockroach allergen Bla g 1 has implications for allergenicity and exposure assessment. J.Allergy Clin.Immunol., 132, 2013
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4DD8
| ADAM-8 metalloproteinase domain with bound batimastat | 分子名称: | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, CALCIUM ION, CHLORIDE ION, ... | 著者 | Hall, T, Shieh, H.S, Day, J.E, Caspers, N, Chrencik, J.E, Williams, J.M, Pegg, L.E, Pauley, A.M, Moon, A.F, Krahn, J.M, Fischer, D.H, Kiefer, J.R, Tomasselli, A.G, Zack, M.D. | 登録日 | 2012-01-18 | 公開日 | 2012-06-06 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of human ADAM-8 catalytic domain complexed with batimastat. Acta Crystallogr.,Sect.F, 68, 2012
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4FO6
| Crystal structure of the pre-catalytic ternary complex of polymerase lambda with a dATP analog opposite a templating T and an rCMP at the primer terminus. | 分子名称: | 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, 5'-D(*CP*AP*GP*TP*AP)-R(P*C)-3', 5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3', ... | 著者 | Gosavi, R.A, Moon, A.F, Kunkel, T.A, Pedersen, L.C, Bebenek, K. | 登録日 | 2012-06-20 | 公開日 | 2012-07-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.007 Å) | 主引用文献 | The catalytic cycle for ribonucleotide incorporation by human DNA Pol lambda Nucleic Acids Res., 40, 2012
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3OB4
| MBP-fusion protein of the major peanut allergen Ara h 2 | 分子名称: | CHLORIDE ION, Maltose ABC transporter periplasmic protein,Arah 2, SULFATE ION, ... | 著者 | Mueller, G.A, Gosavi, R.A, Moon, A.F, London, R.E, Pedersen, L.C. | 登録日 | 2010-08-06 | 公開日 | 2011-02-02 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.706 Å) | 主引用文献 | Ara h 2: crystal structure and IgE binding distinguish two subpopulations of peanut allergic patients by epitope diversity. Allergy, 66, 2011
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3DM0
| Maltose Binding Protein fusion with RACK1 from A. thaliana | 分子名称: | 1,2-ETHANEDIOL, Maltose-binding periplasmic protein fused with RACK1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Ullah, H, Scappini, E.L, Moon, A.F, Williams, L.V, Armstrong, D.L, Pedersen, L.C. | 登録日 | 2008-06-30 | 公開日 | 2008-09-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of a signal transduction regulator, RACK1, from Arabidopsis thaliana. Protein Sci., 17, 2008
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3H4L
| Crystal Structure of N terminal domain of a DNA repair protein | 分子名称: | DNA mismatch repair protein PMS1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Arana, M.E, Holmes, S.F, Fortune, J.M, Moon, A.F, Pedersen, L.C, Kunkel, T.A. | 登録日 | 2009-04-20 | 公開日 | 2010-03-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Functional residues on the surface of the N-terminal domain of yeast Pms1. Dna Repair, 9, 2010
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5T03
| Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and glucuronic acid containing hexasaccharide substrate | 分子名称: | 1,2-ETHANEDIOL, 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, ... | 著者 | Pedersen, L.C, Moon, A.F, Krahn, J.M, Liu, J. | 登録日 | 2016-08-15 | 公開日 | 2017-02-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases. ACS Chem. Biol., 12, 2017
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5T05
| Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and IdoA2S containing hexasaccharide substrate | 分子名称: | 1,2-ETHANEDIOL, 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, ... | 著者 | Pedersen, L.C, Moon, A.F, krahn, J.M, Liu, J. | 登録日 | 2016-08-15 | 公開日 | 2017-02-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | 主引用文献 | Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases. ACS Chem. Biol., 12, 2017
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5T0A
| Crystal Structure of Heparan Sulfate 6-O-Sulfotransferase with bound PAP and heptasaccharide substrate | 分子名称: | 1,2-ETHANEDIOL, 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, ... | 著者 | Pedersen, L.C, Moon, A.F, Krahn, J.M, Liu, J. | 登録日 | 2016-08-15 | 公開日 | 2017-02-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases. ACS Chem. Biol., 12, 2017
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2JW5
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6BKG
| Human LigIV catalytic domain with bound DNA-adenylate intermediate in closed conformation | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... | 著者 | Moon, A.F, Tumbale, P.P, Schellenberg, M.J, Williams, R.S, Williams, J.G, Kunkel, T.A, Pedersen, L.C, Bebenek, B. | 登録日 | 2017-11-08 | 公開日 | 2018-07-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Structures of DNA-bound human ligase IV catalytic core reveal insights into substrate binding and catalysis. Nat Commun, 9, 2018
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6BKF
| Lysyl-adenylate form of human LigIV catalytic domain with bound DNA substrate in open conformation | 分子名称: | ADENOSINE MONOPHOSPHATE, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | 著者 | Moon, A.F, Tumbale, P.P, Schellenberg, M.J, Williams, R.S, Williams, J.G, Kunkel, T.A, Pedersen, L.C, Bebenek, B. | 登録日 | 2017-11-08 | 公開日 | 2018-07-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Structures of DNA-bound human ligase IV catalytic core reveal insights into substrate binding and catalysis. Nat Commun, 9, 2018
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5TYE
| DNA Polymerase Mu Product Complex, 10 mM Mg2+ (60 min) | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Jamsen, J.A, Wilson, S.H. | 登録日 | 2016-11-19 | 公開日 | 2017-08-30 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.047 Å) | 主引用文献 | Time-lapse crystallography snapshots of a double-strand break repair polymerase in action. Nat Commun, 8, 2017
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5TYG
| DNA Polymerase Mu Product Complex, 10 mM Mg2+ (960 min) | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Jamsen, J.A, Wilson, S.H. | 登録日 | 2016-11-19 | 公開日 | 2017-08-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.726 Å) | 主引用文献 | Time-lapse crystallography snapshots of a double-strand break repair polymerase in action. Nat Commun, 8, 2017
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