5T0A
Crystal Structure of Heparan Sulfate 6-O-Sulfotransferase with bound PAP and heptasaccharide substrate
Summary for 5T0A
Entry DOI | 10.2210/pdb5t0a/pdb |
Related | 5T03 5T05 |
Related PRD ID | PRD_900010 |
Descriptor | maltose binding protein - heparan sulfate 6-O-sulfotransferase isoform 3 fusion protein, CHLORIDE ION, 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ... (11 entities in total) |
Functional Keywords | heparan sulfate, sulfotransferase, complex, transferase |
Biological source | Escherichia coli O157:H7 More |
Total number of polymer chains | 2 |
Total formula weight | 164082.10 |
Authors | Pedersen, L.C.,Moon, A.F.,Krahn, J.M.,Liu, J. (deposition date: 2016-08-15, release date: 2017-02-01, Last modification date: 2020-07-29) |
Primary citation | Xu, Y.,Moon, A.F.,Xu, S.,Krahn, J.M.,Liu, J.,Pedersen, L.C. Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases. ACS Chem. Biol., 12:73-82, 2017 Cited by PubMed: 28103688DOI: 10.1021/acschembio.6b00841 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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