5T0A

Crystal Structure of Heparan Sulfate 6-O-Sulfotransferase with bound PAP and heptasaccharide substrate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0006974	biological_process	DNA damage response
A	0008146	molecular_function	sulfotransferase activity
A	0008643	biological_process	carbohydrate transport
A	0015144	molecular_function	carbohydrate transmembrane transporter activity
A	0015768	biological_process	maltose transport
A	0016020	cellular_component	membrane
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0034219	biological_process	carbohydrate transmembrane transport
A	0034289	biological_process	detection of maltose stimulus
A	0042597	cellular_component	periplasmic space
A	0042956	biological_process	maltodextrin transmembrane transport
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0055085	biological_process	transmembrane transport
A	0060326	biological_process	cell chemotaxis
A	0071702	biological_process	organic substance transport
A	1901982	molecular_function	maltose binding
A	1990060	cellular_component	maltose transport complex
B	0005515	molecular_function	protein binding
B	0006974	biological_process	DNA damage response
B	0008146	molecular_function	sulfotransferase activity
B	0008643	biological_process	carbohydrate transport
B	0015144	molecular_function	carbohydrate transmembrane transporter activity
B	0015768	biological_process	maltose transport
B	0016020	cellular_component	membrane
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0034219	biological_process	carbohydrate transmembrane transport
B	0034289	biological_process	detection of maltose stimulus
B	0042597	cellular_component	periplasmic space
B	0042956	biological_process	maltodextrin transmembrane transport
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B	0055085	biological_process	transmembrane transport
B	0060326	biological_process	cell chemotaxis
B	0071702	biological_process	organic substance transport
B	1901982	molecular_function	maltose binding
B	1990060	cellular_component	maltose transport complex

Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
A	PRO107-ASN124

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000305|PubMed:28103688

Chain	Residue	Details
A	HIS1158
B	HIS1158

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site_id	SWS_FT_FI2
Number of Residues	22
Details	BINDING: BINDING => ECO:0000269|PubMed:28103688

Chain	Residue	Details
A	HIS1101
A	THR1323
A	ARG1329
B	HIS1101
B	LYS1131
B	ARG1148
B	TRP1153
B	HIS1158
B	ARG1191
B	SER1199
B	HIS1203
A	LYS1131
B	TRP1210
B	THR1323
B	ARG1329
A	ARG1148
A	TRP1153
A	HIS1158
A	ARG1191
A	SER1199
A	HIS1203
A	TRP1210

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site_id	SWS_FT_FI3
Number of Residues	10
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN1077
B	ASN1393
A	ASN1270
A	ASN1275
A	ASN1326
A	ASN1393
B	ASN1077
B	ASN1270
B	ASN1275
B	ASN1326

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