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3ZUV
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BU of 3zuv by Molmil
Crystal structure of a designed selected Ankyrin Repeat protein in complex with the phosphorylated MAP kinase ERK2
分子名称: DESIGNED ANKYRIN REPEAT PROTEIN, MITOGEN-ACTIVATED PROTEIN KINASE 1, SULFATE ION
著者Kummer, L, Mittl, P.R, Pluckthun, A.
登録日2011-07-20
公開日2012-06-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural and Functional Analysis of Phosphorylation-Specific Binders of the Kinase Erk from Designed Ankyrin Repeat Protein Libraries.
Proc.Natl.Acad.Sci.USA, 109, 2012
2FBE
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BU of 2fbe by Molmil
Crystal Structure of the PRYSPRY-domain
分子名称: PREDICTED: similar to ret finger protein-like 1
著者Gruetter, C, Briand, C, Capitani, G, Mittl, P.R, Gruetter, M.G.
登録日2005-12-09
公開日2006-01-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Structure of the PRYSPRY-domain: Implications for autoinflammatory diseases
Febs Lett., 580, 2006
4PLS
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BU of 4pls by Molmil
Crystal Structures of Designed Armadillo Repeat Proteins: Implications of Construct Design and Crystallization Conditions on Overall Structure.
分子名称: ACETATE ION, Arm00010, CALCIUM ION
著者Reichen, C, Madhurantakam, C, Plueckthun, A, Mittl, P.R.
登録日2014-05-19
公開日2014-12-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structures of Designed Armadillo Repeat Proteins: Implications of Construct Design and Crystallization Conditions on Overall Structure.
Protein Sci., 23, 2014
5AN7
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BU of 5an7 by Molmil
Structure of the engineered retro-aldolase RA95.5-8F with a bound 1,3-diketone inhibitor
分子名称: (2E)-1-(6-methoxynaphthalen-2-yl)but-2-en-1-one, PHOSPHATE ION, RA95.5-8F
著者Obexer, R, Mittl, P.R.E, Hilvert, D.
登録日2015-09-04
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase.
Nat Chem, 9, 2017
1KLX
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BU of 1klx by Molmil
Helicobacter pylori cysteine rich protein B (hcpB)
分子名称: Cysteine Rich Protein B
著者Luethy, L, Gruetter, M.G, Mittl, P.R.E.
登録日2001-12-13
公開日2002-09-11
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The crystal structure of Helicobacter pylori cysteine-rich protein B reveals a novel fold for a penicillin-binding protein.
J.Biol.Chem., 277, 2002
1KKC
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BU of 1kkc by Molmil
Crystal structure of Aspergillus fumigatus MnSOD
分子名称: MANGANESE (II) ION, Manganese Superoxide Dismutase
著者Fluckiger, S, Mittl, P.R.E, Scapozza, L, Fijten, H, Folkers, G, Grutter, M.G, Blaser, K, Crameri, R.
登録日2001-12-07
公開日2001-12-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Comparison of the crystal structures of the human manganese superoxide dismutase and the homologous Aspergillus fumigatus allergen at 2-A resolution.
J.Immunol., 168, 2002
2WL1
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BU of 2wl1 by Molmil
Pyrin PrySpry domain
分子名称: 1,2-ETHANEDIOL, PYRIN, THIOCYANATE ION
著者Weinert, C, Mittl, P.R, Gruetter, M.G.
登録日2009-06-19
公開日2009-10-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献The Crystal Structure of Human Pyrin B30.2 Domain: Implications for Mutations Associated with Familial Mediterranean Fever.
J.Mol.Biol., 394, 2009
2XYH
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BU of 2xyh by Molmil
Caspase-3:CAS60254719
分子名称: 5-CHLORO-4-OXOPENTANOIC ACID, CASPASE-3 SUBUNIT P12, CASPASE-3 SUBUNIT P17
著者Ganesan, R, Jelakovic, S, Grutter, M.G, Mittl, P.R.
登録日2010-11-17
公開日2011-08-17
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献In Silico Identification and Crystal Structure Validation of Caspase-3 Inhibitors without a P1 Aspartic Acid Moiety.
Acta Crystallogr.,Sect.F, 67, 2011
2XYP
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BU of 2xyp by Molmil
Caspase-3:CAS26049945
分子名称: CASPASE-3 SUBUNIT P12, CASPASE-3 SUBUNIT P17, PHENYLMETHYL N-[(2S)-4-CHLORO-3-OXO-1-PHENYL-BUTAN-2-YL]CARBAMATE
著者Ganesan, R, Jelakovic, S, Grutter, M.G, Mittl, P.R.
登録日2010-11-18
公開日2011-08-17
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献In Silico Identification and Crystal Structure Validation of Caspase-3 Inhibitors without a P1 Aspartic Acid Moiety.
Acta Crystallogr.,Sect.F, 67, 2011
2XYG
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BU of 2xyg by Molmil
Caspase-3:CAS329306
分子名称: CASPASE-3 SUBUNIT P12, CASPASE-3 SUBUNIT P17, N-[(2S)-4-chloro-3-oxo-1-phenyl-butan-2-yl]-4-methyl-benzenesulfonamide
著者Ganesan, R, Jelakovic, S, Grutter, M.G, Mittl, P.R.
登録日2010-11-17
公開日2011-08-17
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献In Silico Identification and Crystal Structure Validation of Caspase-3 Inhibitors without a P1 Aspartic Acid Moiety.
Acta Crystallogr.,Sect.F, 67, 2011
4DB6
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BU of 4db6 by Molmil
Designed Armadillo repeat protein (YIIIM3AII)
分子名称: Armadillo repeat protein
著者Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E.
登録日2012-01-13
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-based optimization of designed Armadillo-repeat proteins.
Protein Sci., 21, 2012
4DBA
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BU of 4dba by Molmil
Designed Armadillo repeat protein (YIIM3AII)
分子名称: Designed Armadillo repeat protein, YIIM3AII, GLYCEROL
著者Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E.
登録日2012-01-13
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-based optimization of designed Armadillo-repeat proteins.
Protein Sci., 21, 2012
4DB8
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BU of 4db8 by Molmil
Designed Armadillo-repeat Protein
分子名称: Armadillo-repeat Protein, MAGNESIUM ION
著者Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E.
登録日2012-01-13
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-based optimization of designed Armadillo-repeat proteins.
Protein Sci., 21, 2012
4DB9
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BU of 4db9 by Molmil
Designed Armadillo repeat protein (YIIIM3AIII)
分子名称: Armadillo repeat protein, YIIIM3AIII
著者Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E.
登録日2012-01-13
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-based optimization of designed Armadillo-repeat proteins.
Protein Sci., 21, 2012
1FG2
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BU of 1fg2 by Molmil
CRYSTAL STRUCTURE OF THE LCMV PEPTIDIC EPITOPE GP33 IN COMPLEX WITH THE MURINE CLASS I MHC MOLECULE H-2DB
分子名称: BETA-2 MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, ...
著者Tissot, A.C, Ciatto, C, Mittl, P.R.E, Gruetter, M.G, Plueckthun, A.
登録日2000-07-27
公開日2000-10-04
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.754 Å)
主引用文献Viral escape at the molecular level explained by quantitative T-cell receptor/peptide/MHC interactions and the crystal structure of a peptide/MHC complex.
J.Mol.Biol., 302, 2000
5LE2
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BU of 5le2 by Molmil
Crystal structure of DARPin-DARPin rigid fusion, variant DDD_D12_15_D12_15_D12
分子名称: ACETATE ION, DDD_D12_15_D12_15_D12, THIOCYANATE ION
著者Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A.
登録日2016-06-29
公開日2017-08-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LEC
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BU of 5lec by Molmil
Crystal structure of DARPin-DARPin rigid fusion, variant DDD_D12_12_D12_12_D12
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DDD_D12_12_D12_12_D12
著者Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A.
登録日2016-06-29
公開日2017-08-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.506 Å)
主引用文献Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LEL
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BU of 5lel by Molmil
Crystal structure of DARPin-DARPin rigid fusion, variant DD_Off7_10_3G124 in complex with Maltose-binding Protein and Green Fluorescent Protein
分子名称: DD_Off7_10_3G124, Green fluorescent protein, Maltose-binding periplasmic protein
著者Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A.
登録日2016-06-30
公開日2017-11-15
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LE9
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BU of 5le9 by Molmil
Crystal structure of DARPin-DARPin rigid fusion, variant DD_Off7_09_3G124
分子名称: ACETATE ION, DD_Off7_09_3G124
著者Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A.
登録日2016-06-29
公開日2017-08-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LEE
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BU of 5lee by Molmil
Crystal structure of DARPin-DARPin rigid fusion, variant DDD_D12_12_D12_12_D12
分子名称: DDD_D12_12_D12_12_D12
著者Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A.
登録日2016-06-29
公開日2017-08-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LE8
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BU of 5le8 by Molmil
Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_15_D12
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DD_D12_15_D12, GLYCEROL, ...
著者Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A.
登録日2016-06-29
公開日2017-08-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LE7
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BU of 5le7 by Molmil
Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_13_D12
分子名称: DD_D12_13_D12, SULFATE ION
著者Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A.
登録日2016-06-29
公開日2017-08-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.104 Å)
主引用文献Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LE6
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BU of 5le6 by Molmil
Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_09_D12
分子名称: DD_D12_09_D12, GLYCEROL, SULFATE ION
著者Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A.
登録日2016-06-29
公開日2017-08-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LE4
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BU of 5le4 by Molmil
Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_11_D12
分子名称: DD_D12_11_D12
著者Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A.
登録日2016-06-29
公開日2017-08-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LEA
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BU of 5lea by Molmil
Crystal structure of DARPin-DARPin rigid fusion, variant DD_Off7_12_3G124
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DD_Off7_12_3G124
著者Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A.
登録日2016-06-29
公開日2017-08-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017

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