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5LEL

Crystal structure of DARPin-DARPin rigid fusion, variant DD_Off7_10_3G124 in complex with Maltose-binding Protein and Green Fluorescent Protein

Summary for 5LEL
Entry DOI10.2210/pdb5lel/pdb
DescriptorDD_Off7_10_3G124, Maltose-binding periplasmic protein, Green fluorescent protein (3 entities in total)
Functional Keywordsx-ray crystallography; designed ankyrin repeat proteins; protein design; protein engineering; rigid domain fusions, fluorescent protein
Biological sourcesynthetic construct
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Total number of polymer chains9
Total formula weight319030.92
Authors
Batyuk, A.,Wu, Y.,Mittl, P.R.,Plueckthun, A. (deposition date: 2016-06-30, release date: 2017-11-15, Last modification date: 2019-10-16)
Primary citationWu, Y.,Batyuk, A.,Honegger, A.,Brandl, F.,Mittl, P.R.E.,Pluckthun, A.
Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7:11217-11217, 2017
Cited by
PubMed: 28894181
DOI: 10.1038/s41598-017-11472-x
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.1 Å)
Structure validation

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