3ZUV
Crystal structure of a designed selected Ankyrin Repeat protein in complex with the phosphorylated MAP kinase ERK2
Summary for 3ZUV
Entry DOI | 10.2210/pdb3zuv/pdb |
Related | 1ERK 1GOL 2ERK 2GPH 3ERK 3ZU7 4ERK |
Descriptor | MITOGEN-ACTIVATED PROTEIN KINASE 1, DESIGNED ANKYRIN REPEAT PROTEIN, SULFATE ION, ... (4 entities in total) |
Functional Keywords | de novo protein-transferase complex, ankyrin repeat protein, selected binder, protein design, de novo protein/transferase |
Biological source | RATTUS NORVEGICUS (NORWAY RAT) More |
Cellular location | Nucleus (By similarity): P63086 |
Total number of polymer chains | 4 |
Total formula weight | 114329.96 |
Authors | Kummer, L.,Mittl, P.R.,Pluckthun, A. (deposition date: 2011-07-20, release date: 2012-06-27, Last modification date: 2023-12-20) |
Primary citation | Kummer, L.,Parizek, P.,Rube, P.,Millgramm, B.,Prinz, A.,Mittl, P.R.,Kaufholz, M.,Zimmermann, B.,Herberg, F.W.,Pluckthun, A. Structural and Functional Analysis of Phosphorylation-Specific Binders of the Kinase Erk from Designed Ankyrin Repeat Protein Libraries. Proc.Natl.Acad.Sci.USA, 109:E2248-, 2012 Cited by PubMed: 22843676DOI: 10.1073/PNAS.1205399109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.72 Å) |
Structure validation
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