3ZU7

Crystal structure of a designed selected Ankyrin Repeat protein in complex with the MAP kinase ERK2

Summary for 3ZU7

• Entry DOI: 10.2210/pdb3zu7/pdb
• Related: 1ERK 1GOL 2ERK 2GPH 3ERK 3ZUV 4ERK
• Descriptor: MITOGEN-ACTIVATED PROTEIN KINASE 1, DESIGNED ANKYRIN REPEAT PROTEIN (3 entities in total)
• Functional Keywords: transferase-de novo protein complex, transferase, selected binder, protein design, transferase/de novo protein
• Biological source: RATTUS NORVEGICUS (NORWAY RAT); More
• Cellular location: Cytoplasm, cytoskeleton, spindle : P63086
• Total number of polymer chains: 2
• Total formula weight: 60558.86

Authors

Kummer, L.,Mittl, P.R.,Pluckthun, A. (deposition date: 2011-07-16, release date: 2012-06-27, Last modification date: 2023-12-20)

• Primary citation: Kummer, L.,Parizek, P.,Rube, P.,Millgramm, B.,Prinz, A.,Mittl, P.R.,Kaufholz, M.,Zimmermann, B.,Herberg, F.W.,Pluckthun, A.; Structural and Functional Analysis of Phosphorylation-Specific Binders of the Kinase Erk from Designed Ankyrin Repeat Protein Libraries.; Proc.Natl.Acad.Sci.USA, 109:E2248-, 2012; PubMed: 22843676; DOI: 10.1073/PNAS.1205399109

Experimental method

X-RAY DIFFRACTION (1.97 Å)