2GPH
Docking motif interactions in the MAP kinase ERK2
Summary for 2GPH
Entry DOI | 10.2210/pdb2gph/pdb |
Descriptor | Mitogen-activated protein kinase 1, Tyrosine-protein phosphatase non-receptor type 7 (3 entities in total) |
Functional Keywords | erk2, docking interaction, d-motif, allostery, cd-site, phosphatase-derived peptide, processing conformation, transferase |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Cytoplasm, cytoskeleton, spindle : P63086 Cytoplasm : P35236 |
Total number of polymer chains | 2 |
Total formula weight | 44025.65 |
Authors | Zhou, T.,Sun, L.,Humphreys, J.,Goldsmith, E.J. (deposition date: 2006-04-17, release date: 2006-07-04, Last modification date: 2023-08-30) |
Primary citation | Zhou, T.,Sun, L.,Humphreys, J.,Goldsmith, E.J. Docking Interactions Induce Exposure of Activation Loop in the MAP Kinase ERK2. Structure, 14:1011-1019, 2006 Cited by PubMed: 16765894DOI: 10.1016/j.str.2006.04.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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