2GPH
Docking motif interactions in the MAP kinase ERK2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Mitogen-activated protein kinase 1 | polymer | 364 | 42161.5 | 1 | UniProt (P63086) Pfam (PF00069) In PDB | Rattus norvegicus (Norway rat) | Extracellular signal-regulated kinase 2, ERK-2, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, p42-MAPK, ERT1 |
2 | B | Tyrosine-protein phosphatase non-receptor type 7 | polymer | 16 | 1864.2 | 1 | UniProt (P35236) In PDB | Protein-tyrosine phosphatase LC-PTP, Hematopoietic protein-tyrosine phosphatase, HEPTP | |
3 | water | water | 18.0 | 290 | Chemie (HOH) |
Sequence modifications
A: 2 - 358 (UniProt: P63086)
B: 16 - 31 (UniProt: P35236)
PDB | External Database | Details |
---|---|---|
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Met 1 | - | cloning artifact |
Cys 116 | Thr 115 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Cys 31 | Val 52 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 44025.7 | |
All* | Total formula weight | 44025.7 |