3ZU7

Crystal structure of a designed selected Ankyrin Repeat protein in complex with the MAP kinase ERK2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	MITOGEN-ACTIVATED PROTEIN KINASE 1	polymer	365	42230.5	1	UniProt (P63086) Pfam (PF00069) In PDB	RATTUS NORVEGICUS (NORWAY RAT)	MAP KINASE 1, MAPK 1, ERT1, EXTRACELLULAR SIGNAL-REGULATED KINASE 2, ERK-2, MAP KINASE ISOFORM P42, P42-MAPK, MITOGEN-ACTIVATED PROTEIN KINASE 2, MAP KINASE 2, MAPK 2
2	B	DESIGNED ANKYRIN REPEAT PROTEIN	polymer	169	18328.4	1		SYNTHETIC CONSTRUCT
3		water	water		18.0	236	Chemie (HOH)

Sequence modifications

A: 3 - 358 (UniProt: P63086)

PDB	External Database	Details
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Ala 1	-	expression tag
Met 2	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	60558.9
All*	Total formula weight	60558.9

*Water molecules are not included.