5LE2
Crystal structure of DARPin-DARPin rigid fusion, variant DDD_D12_15_D12_15_D12
Summary for 5LE2
Entry DOI | 10.2210/pdb5le2/pdb |
Descriptor | DDD_D12_15_D12_15_D12, THIOCYANATE ION, ACETATE ION, ... (4 entities in total) |
Functional Keywords | x-ray crystallography; designed ankyrin repeat proteins; protein design; protein engineering; rigid domain fusions, de novo protein |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 106498.53 |
Authors | Batyuk, A.,Wu, Y.,Mittl, P.R.,Plueckthun, A. (deposition date: 2016-06-29, release date: 2017-08-02, Last modification date: 2024-01-10) |
Primary citation | Wu, Y.,Batyuk, A.,Honegger, A.,Brandl, F.,Mittl, P.R.E.,Pluckthun, A. Rigidly connected multispecific artificial binders with adjustable geometries. Sci Rep, 7:11217-11217, 2017 Cited by PubMed: 28894181DOI: 10.1038/s41598-017-11472-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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