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3Q33
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BU of 3q33 by Molmil
Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation
分子名称: 1,2-ETHANEDIOL, ACETYL COENZYME *A, HISTONE H3, ...
著者Tang, Y, Yuan, H, Meeth, K, Marmorstein, R.
登録日2010-12-21
公開日2011-02-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation.
Structure, 19, 2011
3BY4
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BU of 3by4 by Molmil
Structure of Ovarian Tumor (OTU) domain in complex with Ubiquitin
分子名称: 3-AMINOPROPANE, Ubiquitin, Ubiquitin thioesterase OTU1
著者Messick, T.E, Marmorstein, R.
登録日2008-01-15
公開日2008-02-19
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein
J.Biol.Chem., 283, 2008
3C0R
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BU of 3c0r by Molmil
Structure of Ovarian Tumor (OTU) domain in complex with Ubiquitin
分子名称: 3-AMINOPROPANE, Ubiquitin, Ubiquitin thioesterase OTU1
著者Messick, T.E, Marmorstein, R.
登録日2008-01-21
公開日2008-02-19
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.315 Å)
主引用文献Structural basis for ubiquitin recognition by the Otu1 ovarian tumor domain protein
J.Biol.Chem., 283, 2008
5WI2
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BU of 5wi2 by Molmil
Crystal structure of the KA1 domain from human Chk1
分子名称: ACETATE ION, GLYCEROL, cDNA FLJ56409, ...
著者Emptage, R.P, Marmorstein, R.
登録日2017-07-18
公開日2017-10-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.495 Å)
主引用文献Intramolecular autoinhibition of checkpoint kinase 1 is mediated by conserved basic motifs of the C-terminal kinase-associated 1 domain.
J. Biol. Chem., 292, 2017
6O07
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BU of 6o07 by Molmil
Structure and mechanism of acetylation by the N-terminal dual enzyme NatA/Naa50 complex
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETYL COENZYME *A, CHLORIDE ION, ...
著者Deng, S, Marmorstein, R.
登録日2019-02-15
公開日2019-06-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Structure and Mechanism of Acetylation by the N-Terminal Dual Enzyme NatA/Naa50 Complex.
Structure, 27, 2019
1TRO
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BU of 1tro by Molmil
CRYSTAL STRUCTURE OF TRP REPRESSOR OPERATOR COMPLEX AT ATOMIC RESOLUTION
分子名称: DNA (5'-D(*TP*GP*TP*AP*CP*TP*AP*GP*TP*TP*AP*AP*CP*TP*AP*GP*T P*AP*C)-3'), PROTEIN (TRP REPRESSOR), TRYPTOPHAN
著者Otwinowski, Z, Schevitz, R.W, Zhang, R.-G, Lawson, C.L, Joachimiak, A, Marmorstein, R, Luisi, B.F, Sigler, P.B.
登録日1992-08-30
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of trp repressor/operator complex at atomic resolution.
Nature, 335, 1988
6POE
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BU of 6poe by Molmil
Structure of ACLY in complex with CoA
分子名称: ATP-citrate synthase, COENZYME A
著者Wei, X, Marmorstein, R.
登録日2019-07-03
公開日2019-12-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
7LJ9
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BU of 7lj9 by Molmil
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate
分子名称: ACETYL COENZYME *A, ATP-citrate synthase, OXALOACETATE ION
著者Wei, X, Marmorstein, R.
登録日2021-01-28
公開日2021-03-31
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
8ETB
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BU of 8etb by Molmil
the crystal structure of a rationally designed zinc sensor based on maltose binding protein - Zn binding conformation
分子名称: ACETATE ION, ZINC ION, Zinc Sensor protein
著者Zhao, Z, Zhou, M, Zemerov, S.D, Marmorstein, R, Dmochowski, I.J.
登録日2022-10-16
公開日2023-03-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Rational design of a genetically encoded NMR zinc sensor.
Chem Sci, 14, 2023
8F23
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BU of 8f23 by Molmil
The crystal structure of a rationally designed zinc sensor based on maltose binding protein - Apo conformation
分子名称: Zinc Sensor protein
著者Zhao, Z, Zhou, M, Zemerov, S.d, Marmorstein, R, Dmochowski, I.J.
登録日2022-11-06
公開日2023-03-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Rational design of a genetically encoded NMR zinc sensor.
Chem Sci, 14, 2023
4DAW
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BU of 4daw by Molmil
Crystal structure of PAK1 kinase domain with the ruthenium phthalimide complex
分子名称: Serine/threonine-protein kinase PAK 1, [1,3-dioxo-6-(pyridin-2-yl-kappaN)-2,3-dihydro-1H-isoindol-5-yl-kappaC~5~][(thioxomethylidene)azanido-kappaN](1,4,7-trithionane-kappa~3~S~1~,S~4~,S~7~)ruthenium
著者Maksimoska, J, Marmorstein, R.
登録日2012-01-13
公開日2012-03-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The art of filling protein pockets efficiently with octahedral metal complexes.
Angew.Chem.Int.Ed.Engl., 51, 2012
9B3T
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BU of 9b3t by Molmil
Octameric prenyltransferase domain of linkerless Fusicoccadiene synthase with C2 symmetry without associated cyclase domains
分子名称: Fusicoccadiene synthase
著者Wenger, E.S, Schultz, K, Marmorstein, R, Christianson, D.W.
登録日2024-03-20
公開日2024-09-25
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Engineering substrate channeling in a bifunctional terpene synthase.
Proc.Natl.Acad.Sci.USA, 121, 2024
1QST
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BU of 1qst by Molmil
CRYSTAL STRUCTURE OF TETRAHYMENA GCN5
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, TGCN5 HISTONE ACETYL TRANSFERASE
著者Rojas, J.R, Trievel, R.C, Zhou, J, Mo, Y, Li, X, Berger, S.L, David Allis, C, Marmorstein, R.
登録日1999-06-23
公開日1999-09-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide.
Nature, 401, 1999
1QSN
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BU of 1qsn by Molmil
CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 WITH BOUND COENZYME A AND HISTONE H3 PEPTIDE
分子名称: COENZYME A, HISTONE H3, TGCN5 HISTONE ACETYL TRANSFERASE
著者Rojas, J.R, Trievel, R.C, Zhou, J, Mo, Y, Li, X, Berger, S.L, David Allis, C, Marmorstein, R.
登録日1999-06-22
公開日1999-09-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide.
Nature, 401, 1999
3LBX
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BU of 3lbx by Molmil
Crystal Structure of the Erythrocyte Spectrin Tetramerization Domain Complex
分子名称: Spectrin alpha chain, erythrocyte, Spectrin beta chain
著者Ipsaro, J.J, Harper, S.L, Messick, T.E, Marmorstein, R, Mondragon, A, Speicher, D.W.
登録日2010-01-08
公開日2010-03-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex.
Blood, 115, 2010
3BIY
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BU of 3biy by Molmil
Crystal structure of p300 histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA
分子名称: BROMIDE ION, Histone acetyltransferase p300, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl dihydrogen diphosphate
著者Liu, X, Wang, L, Zhao, K, Thompson, P.R, Hwang, Y, Marmorstein, R, Cole, P.A.
登録日2007-12-02
公開日2008-02-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The structural basis of protein acetylation by the p300/CBP transcriptional coactivator
Nature, 451, 2008
3FXZ
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BU of 3fxz by Molmil
Crystal structure of PAK1 kinase domain with ruthenium complex lambda-FL172
分子名称: OCTAHEDRAL RU-PYRIDOCARBAZOLE, Serine/threonine-protein kinase PAK 1
著者Maksimoska, J, Marmorstein, R, Meggers, E.
登録日2009-01-21
公開日2009-02-17
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes
J.Am.Chem.Soc., 130, 2008
6UIA
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BU of 6uia by Molmil
Structure of ATP citrate lyase with CoA in a partially open conformation
分子名称: ATP-citrate synthase, COENZYME A
著者Wei, X, Marmorstein, R.
登録日2019-09-30
公開日2019-12-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
2QIY
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BU of 2qiy by Molmil
yeast Deubiquitinase Ubp3 and Bre5 cofactor complex
分子名称: UBP3-associated protein BRE5, Ubiquitin carboxyl-terminal hydrolase 3
著者Li, K, Liu, X, Marmorstein, R.
登録日2007-07-05
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Molecular basis for bre5 cofactor recognition by the ubp3 deubiquitylating enzyme.
J.Mol.Biol., 372, 2007
1IHB
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BU of 1ihb by Molmil
CRYSTAL STRUCTURE OF P18-INK4C(INK6)
分子名称: CYCLIN-DEPENDENT KINASE 6 INHIBITOR
著者Ravichandran, V, Swaminathan, K, Marmorstein, R.
登録日1997-10-25
公開日1998-12-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the CDK4/6 inhibitory protein p18INK4c provides insights into ankyrin-like repeat structure/function and tumor-derived p16INK4 mutations.
Nat.Struct.Biol., 5, 1998
8G0L
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BU of 8g0l by Molmil
Semi-synthetic CoA-alpha-Synuclein Constructs Trap N-terminal Acetyltransferase NatB for Binding Mechanism Studies
分子名称: Alpha-synuclein, CARBOXYMETHYL COENZYME *A, N-alpha-acetyltransferase 20, ...
著者Gardner, S.M, Marmorstein, R.
登録日2023-01-31
公開日2023-05-03
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Semi-Synthetic CoA-alpha-Synuclein Constructs Trap N-Terminal Acetyltransferase NatB for Binding Mechanism Studies.
J.Am.Chem.Soc., 145, 2023
5DFP
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BU of 5dfp by Molmil
Crystal structure of PAK1 in complex with an inhibitor compound FRAX1036
分子名称: 6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-{[2-(1-methylpiperidin-4-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, DIMETHYL SULFOXIDE, Serine/threonine-protein kinase PAK 1
著者Maksimoska, J, Marmorstein, R, Wang, W.
登録日2015-08-27
公開日2016-01-27
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety.
Acs Med.Chem.Lett., 6, 2015
1K6O
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BU of 1k6o by Molmil
Crystal Structure of a Ternary SAP-1/SRF/c-fos SRE DNA Complex
分子名称: 5'-D(*CP*AP*CP*AP*GP*GP*AP*TP*GP*TP*CP*CP*AP*TP*AP*TP*TP*AP*GP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*CP*TP*AP*AP*TP*AP*TP*GP*GP*AP*CP*AP*TP*CP*CP*TP*GP*TP*G)-3', ETS-domain protein ELK-4, ...
著者Mo, Y, Ho, W, Johnston, K, Marmorstein, R.
登録日2001-10-16
公開日2002-01-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex.
J.Mol.Biol., 314, 2001
7LLA
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BU of 7lla by Molmil
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate (EM map was generated in Cryosparc with non-uniform refinement)
分子名称: ACETYL COENZYME *A, ATP-citrate synthase, OXALOACETATE ION
著者Wei, X, Marmorstein, R.
登録日2021-02-03
公開日2021-03-03
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
5ICV
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BU of 5icv by Molmil
Crystal structure of human NatF (hNaa60) bound to a bisubstrate analogue
分子名称: MET-LYS-ALA-VAL-LIG, N-alpha-acetyltransferase 60, [5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)furan-2-yl]methyl (3R)-4-{[3-({(E)-2-[(2,2-dihydroxyethyl)sulfanyl]ethenyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl dihydrogen diphosphate
著者Stove, S.I, Magin, R.S, Marmorstein, R, Arnesen, T.
登録日2016-02-23
公開日2016-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Crystal Structure of the Golgi-Associated Human N alpha-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation.
Structure, 24, 2016

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