3LBX

Crystal Structure of the Erythrocyte Spectrin Tetramerization Domain Complex

Summary for 3LBX

• Entry DOI: 10.2210/pdb3lbx/pdb
• Related: 1AJ3 1OWA 2SPC 3EDV 3F31 3KBT
• Descriptor: Spectrin alpha chain, erythrocyte, Spectrin beta chain, erythrocyte (2 entities in total)
• Functional Keywords: spectrin, tetramer, complex, three-helix bundle, alpha helix, partial repeat, helical linker, actin capping, actin-binding, cell shape, cytoskeleton, disease mutation, elliptocytosis, hereditary hemolytic anemia, pyropoikilocytosis, sh3 domain, phosphoprotein, structural protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, cytoskeleton: P02549 P11277
• Total number of polymer chains: 2
• Total formula weight: 40715.97

Authors

Ipsaro, J.J.,Harper, S.L.,Messick, T.E.,Marmorstein, R.,Mondragon, A.,Speicher, D.W. (deposition date: 2010-01-08, release date: 2010-03-09, Last modification date: 2024-02-21)

• Primary citation: Ipsaro, J.J.,Harper, S.L.,Messick, T.E.,Marmorstein, R.,Mondragon, A.,Speicher, D.W.; Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex.; Blood, 115:4843-4852, 2010; PubMed: 20197550; DOI: 10.1182/blood-2010-01-261396

Experimental method

X-RAY DIFFRACTION (2.8 Å)